Doctor insights on:
Syphilis Treponema Pallidum
Obligate parasite.: Treponema pallidum is the pathogen that causes syphilis. It is very difficult to grow in culture because unlike most bacteria, it cannot survive outside of mammalian cells (i.e. On a petri dish), thus it is considered an obligate parasite. It has limited metabolic capacity, and cannot synthesize many biomolecules, which it requires from a living host. This has posed a hurdle for researchers. ...Read more
Depends: T.Pallidum, the germ cause of syphilis can pass from mother to child in any stage of pregnancy. The effect on the embryo or fetus ranges from death to major multiple-organ disease to a mild neonatal form that may be overlooked, but can cause long term defects. Ob's typically screen early & late in pregnancy to find & treat this condition as soon as possible. Newborns may have meningitis. ...Read more
What could cause chronic joint pain (most joints) in otherwise healthy 25 yo male? Rf, ana, treponema pallidum, sedimentation rate all normal.
Inflammation: Inflammation has many possible causes. There is the possibility of seronegative RA (ra test is negative); given that all of your tests are negative focus on nutritional causes. Stop all acid intake especially sodas; increase antioxidant intake and herbal antiinflammatories and a new product on the market that has been shown to reduce oxidative stress to near nothing. Www. Medacpc. Com for more. ...Read more
How could syphilis test be negative and anticardiolipin autoantibody be positive? Do some syphilis tests only look for antibodies to t. Pallidum?
Primary: Syphilis has three phases. Primary, secondary and tertiary and each is quite different in its presentation. Primary syphilis usually shows what is termed a hard chancre. This is a skin ulcer with raised edges and a firm non-tender center. It can appear anywhere the organism entered your body, usually on the genetalia or the mucous membranes of the mouth (tongue is not uncommon). ...Read more
Absolutely: The Tuskeegee study, in which mostly black men in the US south known to have syphilis were followed until they became symptomatic with the advanced disease rather than being treated, was a crime. However, it left no doubt that one can indeed die of syphilis. Even today, one occasionally sees neurosyphilis or a ruptured thoracic aneurysm. ...Read more
Many diseases can cause periostitis & bone softening, syphilis being one of them. Anterior bowing is "…due to abnormal weightbearing" according to extract from imaging of tropical diseases: with epidemiological, pathological. .., volume 2
by philip e. S. Palmer, maurice merrick reeder. ...Read more
Penicillin: Injectable (intramuscular) penicillin remaims the treatment of choice for all stages of syphilis. If the patient is penicillin allergic, other choices include tetracyclines, macrolides, such as erthromycin and ceftriaxone. Duration of therapy depends on the stage of the disease. Some of the non penicillin treatments suffer from antibiotic resistance. Follow up to insure cure is advised. ...Read more
Depends: Rx for syphillis depends on the type, newborn or acquired;stage, early or late and complications. Penicillin is the primary drug treatment. Management of new cases includes parameters such as detecting other std's, finding & treating exposed contacts, etc. Followup includes testing to be sure the initial treatment is successful. ...Read more