Doctor insights on:
Syphilis Treatment Dosage
I am taking azithromycin 500mg for three days for syphilis treatment and I've already taken it for two days. Now I'm told to take 2g single dose.
Penicillin: Injectable (intramuscular) penicillin remaims the treatment of choice for all stages of syphilis. If the patient is penicillin allergic, other choices include tetracyclines, macrolides, such as erthromycin and ceftriaxone. Duration of therapy depends on the stage of the disease. Some of the non penicillin treatments suffer from antibiotic resistance. Follow up to insure cure is advised. ...Read more
Depends: Rx for syphillis depends on the type, newborn or acquired;stage, early or late and complications. Penicillin is the primary drug treatment. Management of new cases includes parameters such as detecting other std's, finding & treating exposed contacts, etc. Followup includes testing to be sure the initial treatment is successful. ...Read more
Depends on form: The preferred treatment for newly acquired (primary)syphillis is a single dose of penicillin g with avoidance of sexual activity until any primary leasons are healed. Followup blood tests at 6 & 12 months are recomended to verify the success of initial treatment or recurrance. Weekly pcn x3 is recomended for latent disease. Since other std's often co-exist variations in rx are often needed. ...Read more
After being diagnosed with syphilis and given your first treatment how long does it take for the shot to work. Am I gonna go through the secondary stg?
Not if treated: You ought to follow up with your doctor to ensure that treatment was successful. It may require serial tests. If the treatment is successful, you will not go through secondary or tertiary stage. ...Read more
IV Penicillin.: Late infections need IV penicillin for at least 10 days. If the patient is allergic Ceftriaxone can be used. Other kinds of late disease may be treated with once-weekly intramuscular penicillin g for three weeks. If allergic, Doxycycline or tetracycline may be used, for a longer duration. These treatments can stop further progression, but not fully reverse damage already done. ...Read more
Clarify please---: "end stage" syphilis is not considered a diagnostic classification. We classify syphilitic infections based on: 1) time from 1st infection (early, late, and late-lantent) 2) syndromes (primary, secondary, tertiary), and 3) CNS effects (neurosyphilis). In all these cases, your treatment options are limited to IV penicillin (for neurosyphilis) or benzithene penicillin (all other forms)- no subs. ...Read more
Syphilis: Yes. But they are not as effective. Many doctors will treat with the second line therapies unless there is brain involvement or a treatment failure to eradicate the syphilis. In this event they work to temporarily desensitize the patient of their penicillin allergy and then give the better treatment. ...Read more
What will be effect if we take syphilis treatment as early as possible after unsafe sex without examination?
Treating before test: Syphilis can sometimes be hard to treat and it is always good to get a test drawn before treatment so that the correct antibody titters can be followed. But I have treated some patients with high risk exposure before they could test positive. I would like to know more about the situation you are confronting. ...Read more
Treatment for syphilis in 2012. Titer went down to 1:1, f/u 6 months later was non-reactive. Latest f/u at 1 year was 1:1 again. No new exposure. Bad?
No: Rises in titer only count if they're 2-dilution rises. From non-reactive to 1:1 is a 1-dilution rise, and is not felt to be significant. A rise from non-reactive to 1:2 would be significant. However, if you were re-infected with syphilis, your titer would probably be much higher than 1:2. ...Read more
We come from a religious background where treatment is based on faith and home cures. What can we use to treat end stage syphilis?
See a doctor: If you're saying that you have been treating syphilis with home cures, and it has progressed to the tertiary stage, that should tell you something: you could have resolved the problem at an early stage with a shot of penicillin. Since you didn't, you have a significant problem, since tertiary syphilis is quite difficult to treat. See a qualified physician immediately. ...Read more
Can I get syphilis by holding hands with a person who has undergone the treatment for syphilis for the past year?
No risk: Treatment for syphilis is quite effective and usually by two weeks the organism is eliminated. Transmission requires intimate contact through mucus linings. Holding hands is sweet and will not transmit syphilis which I believe is not now present in this formerly infected person. ...Read more
I have been tested positive for syphilis score of 1:16 started penicillin treatment today. Can I just get hiv? Or does this mean I will later get hiv?
It depends: It all depends on what the treatment was. But, days is usually the best answer we can give. ...Read more
Stage 2 Syphilis 1:256 treated w/ penicillin. Rash came back 8 months later. Retest titer1:64. 4fold decrease successful treatment so why isrash back?
Rash: It may not be from the same cause. Obviously, I would suggest being evaluated for HIV (I assume that you have), since acquiring one STI may be associated with another infection. Are you on Remicade for Crohn's? Any new medications? Usually the titers are rechecked after six months for a fourfold reduction which is in your case. Look for an alternative cause - recent antibiotic exposure? Etc ...Read more
I'm just wondering, if you are infected with syphilis and Lyme disease would regular antibiotic treatment work?
Can a woman with syphilis give birth to a healthy new baby, as long as she got antibiotic treatment?
Yes: As long as pregnant mother gets proper treatment and follow-ups. ...Read more
Is annual STD screening frequent enough to catch potentially asymptomatic STDs (like syphilis) in a timely manner for their treatment? (Not high risk)
I asked yesterday, with some conflicting answers, so I am seeing if some other docs with answer. Is someone contagious with syphilis 24 hours after penicillin therapy. Can they transmit?
How long does it take before syphilis rash on back goes away? Was Diagnosed with neuropsyphilis and IV therapy of penicillin has been completed.
Should have cleared: The skin rash of secondary syphilis typically clears up within a few days of starting penicillin. Any rash persisting 10+ days (the usual duration of IV pen for NS) probably wasn't syphilis, and syphilis rash usuallyis body wide, not one area like the back. Maybe penicillin allergy if it started after treatment began. In any case, show it to your doctor. Good luck! ...Read more
Taking Amox-Clav 875mg/2x day/10 days for NGU. Possibly exposed to syphilis within last week. Is A-C also effective against syphilis at this dosage?
WRONG ANTIBIOTICS: Syphilis is treated by an injection of Benzathene Penicillin.How do you know you were exposed to Syphilis. My advice is to consult your doctor or clinic and seriously learn about how to have safe sex.If you have been having high risk sex without protection. There will continue to be risk of STDs including HIV.And you should be chcked for it. And Amox-Clav is not the drug of choice for NGU ...Read more
Syphilis: Doxycycline can be a cure to syphilis but it is not the most effective treatment. There is a special Penicillin known as Bicillin or Penacillin G that at 2.4 million units is 100% curative. Syphilis is experienced in three phases but there are often no symptom between phases. Blood testing and antibody titer monitoring are the norms for making sure the treatment was effective. ...Read more
Never too late to Rx: Syphilis progresses in 3 stages, the initial sore, the blood borne spirochete, and finally crossing the blood brain barrier. Unlike the carol king song "it's too late" from her tapestry album, we rarely see 3rd stage disease because it is usually caught and treated prior to infiltrating the brain. Can that happen in 9 untreated months? It depends on the hosts' resistance and the rapidity of rx. ...Read more
7 days: 1 injection of benzathine penicillin will cure secondary syphillis. It will maintain blood levels of penicillin for over 15 days. It takes 7 days of continuous penicillin levels in the blood to cure secondary syphillis. ...Read more
If I was treated with the appropriate shot of penicillin one day after possible exposure to Syphilis, is this enough to cure it?
Yes and no: In many parts of the world, including much of the US and Europe, syphilis bacteria are resistant to azithromcyin, so it is not used or recommended for treatment or prevention. However, it is effective and sometimes used where resistance isn't a problem, such as many parts of Africa. ...Read more