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Doctor insights on: Synthroid Not Working

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Dr. David Sneid
1,445 doctors shared insights

Thyroxine (Definition)

Thyroxine is a thyroid ...Read more


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If Synthroid (thyroxine) isn't working, would armour work better because it isn't synthetic?

If Synthroid (thyroxine) isn't working, would armour work better because it isn't synthetic?

No: Synthroid (thyroxine) takes several weeks to take effect. You need to be patient and follow your doctors instructions. The dose will probably need to be adjusted over the next several months. Armour is an outdated form of treatment for hypothyroidism and is not as effective. ...Read more

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Do you find that Synthroid (thyroxine) works better then the generic levothyrxoine? I've heard that many people/doctors feel that Synthroid (thyroxine) is better.

Do you find that Synthroid (thyroxine) works better then the generic levothyrxoine? I've heard that many people/doctors feel that Synthroid (thyroxine) is better.

Yes: Dosage of thryoid replacement therapy must be very precise. Generic medications can vary in potency or bioavailability by 20%. Brand name medications always deliver the same amount of product. Because of the narrow dosing range, it is better to take a more reliable product--synthroid rather than generic levothyroxine. ...Read more

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Why you shouldn't take antacids with synthroid (thyroxine)?

Why you shouldn't take antacids with synthroid (thyroxine)?

Absorption: Thyroid meds must be taken on an empty stomach for proper absorption. That means nothing but water for one hour after taking or 2h before taking meds. Vitamins and minerals need to be taken at least 4 hours away from thyroid. A new medication tirosint claims no fasting necessary however. ...Read more

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What can I use to replace Armour Thyroid meds?.I do not tolerate Synthroid (thyroxine) or levitroid?

"do not tolerate ..': do not tolerate synthroid (thyroxine) or levothroid means you don't have correct dose!! the chemical in them is exact same chemical your body produces ...Read more

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Can not taking your Synthroid (thyroxine) meds make you emotional ?

Can not taking your Synthroid (thyroxine) meds make you emotional ?

Possibly: Effects of too little thyroid can vary from one person to the next. Some people can become depressed, moody, or tearful with this. It make take a few weeks back on the the synthroid (thyroxine) to get things back to normal, so please don't delay! ...Read more

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Does taking cytomel or Synthroid (thyroxine) to help lose weight?

Does taking cytomel or Synthroid (thyroxine) to help lose weight?

Thyroid weight loss: Thyroid hormones should never be used for weight loss. They may increase your metabolic rate, but will also increase appetite. And there is a large potential for side effects. Beside making you feel nervous, jittery, sweaty, they accelerate your heart to the point of serious problems and can cause mental health problems. ...Read more

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Is armour/dessicated thyroid med really better than synthroid (thyroxine)?

Is armour/dessicated thyroid med really better than synthroid (thyroxine)?

No.: The short answer is no, there are no studies to show that desicated thyroid or Armour Thyroid are better than synthroid (thyroxine). You definitely should have this discussion with your endocrinologist, however. ...Read more

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Will diet pills affect my Synthroid (thyroxine) medication. I'm looking into the natural garcinia pill. But i take Synthroid (thyroxine) for thyroid.

Will diet pills affect my Synthroid (thyroxine) medication. I'm looking into the natural garcinia pill. But i take Synthroid (thyroxine) for thyroid.

No Diet Pills work: Please save your money. There is still no diet pill that will really lead you to real and lasting weight loss. Please do not be gullible to this one more product designed to take money from the overweight. ...Read more

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Is it better to take the name brand Synthroid (thyroxine) than thegeneric brand.I am taking the generic but I feel I would feel better on Synthroid (thyroxine) is there bette?

Is it better to take the name brand Synthroid (thyroxine) than thegeneric brand.I am taking the generic but I feel I would feel better on Synthroid (thyroxine) is there bette?

Same Hormone with a: twist. Each manufacturer uses the same levothyroxine hormone, and puts the correct amount in each pill. The difference between different manufacturers is the binders they use to actually make the pill. These different binders can change the absorption of the hormone, and since we are only taking about micrograms of the hormone in the pill, a little difference in absorption makes a big change. ...Read more

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If I was not compliant with taking Synthroid (thyroxine) will heart pills like amiodarone make me feel worst?

If I was not compliant with taking Synthroid (thyroxine) will heart pills like amiodarone make me feel worst?

Yes: In general, not taking medications that were prescribed to you in the way they were prescribed is not healthy. Sometimes this will not make you feel bad (cholesterol medicine, eg), but other times like with levothyroxine (synthroid), this will leave you hypothyroid, which can make you feel tired, constipated, cold, depressed, etc. This is irrespective of whether you were compliant with amio or not. ...Read more

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I'm taking Synthroid (thyroxine) med once a day and I started taking Herbalife would that in interfere?

I'm taking Synthroid (thyroxine) med once a day and I started taking Herbalife would that in interfere?

Food interactions: To my knowledge, foods like dietary fiber, soybean flower, cottonseed meal, walnuts, calcium and calcium-fortified juices can affect the absorption of levothyroxin Syntroid & interfere with maintaining steady blood levels. So take these foods at the same time each day; and, if possible, avoid taking them within several hours of taking your levothyroxin. Hope that helps. ...Read more

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What to do if you develop post-partum thyroiditis (hyperactive) and am taking synthroid (thyroxine)? Can I stop synthroid (thyroxine) cold turkey?

What to do if you develop post-partum  thyroiditis (hyperactive) and am taking synthroid (thyroxine)? Can I stop synthroid (thyroxine) cold turkey?

Endocrinologist: You should be under the care of an endocrinologist or thyroidologist. With acute thyroiditis thyroid hormone is released into the system causing hyperthyroidism and synthroid (thyroxine) aggravates the situation and can be stopped abruptly if thyroid hormone overload is occurring. Treatment and follow-up should be directed by a specialist in thyroid disorders and advice regarding breast feeding is needed ...Read more

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Does it take longer for Synthroid (thyroxine) to work vs. Levothyroid?

Does it take longer for Synthroid (thyroxine) to work vs. Levothyroid?

Not really: Absorption of each thyroid preparation is a little different, and you should not switch brands, if possible. But both synthroid (thyroxine) and Levothroid are long acting hormones, with a half-life of 1 week. I doubt you would notice a difference with regards to onset of action, for example if you were starting to take them for hypothyroidism. ...Read more

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Are the brand name "synthroid" &levothyroxine equally effective? M taking synthroid. Can I switch 2 levothyroxine, looks like levothyroxine is cheaper

Are the brand name "synthroid" &levothyroxine equally effective? M taking synthroid. Can I switch 2 levothyroxine, looks like levothyroxine is cheaper

Levothyroxine is: cheaper since it's a generic, but the blood levels with Synthroid (thyroxine) are more consistent and reliable. It is a product with a "narrow therapeutic window" where generics can vary from batch to batch, company to company and prescription to prescription -- while the brand name product does not. If you can afford it, take the brand name drug. ...Read more

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If Synthroid (thyroxine) isn't working, would armour work better because it isn't synthetic?

No: Synthroid (thyroxine) takes several weeks to take effect. You need to be patient and follow your doctors instructions. The dose will probably need to be adjusted over the next several months. Armour is an outdated form of treatment for hypothyroidism and is not as effective. ...Read more

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My doctor is refusing to believe me when I tell him my Synthroid (thyroxine) isn't working after many doses and many years. what should I do?

My doctor is refusing to believe me when I tell him my Synthroid (thyroxine) isn't working after many doses and many years. what should I do?

Symptoms: How can you tell if Synthroid (thyroxine) works or not? What are your symptoms like? Is it possible that your symptoms are due to a different condition? Synthroid (thyroxine) is the branded thyroid drug. I had few patients that ended up on Armour thyroid. An endocrinology consult might help. ...Read more

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What stops thyroxine from working?

When you stop taking: Thyroxin stops working only when you stop taking it. ...Read more

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If I have been using Synthroid (thyroxine) for years and it isn't working, should I ask about armour or something not synthetic?

If I have been using Synthroid (thyroxine) for years and it isn't working, should I ask about armour or something not synthetic?

There is: no such thing as Synthroid (thyroxine) "not working". If you take the proper dose to keep your levels normal, it's working. If you have other problems, they are not due to your hypothyroidism. Synthroid (thyroxine) is an exact duplicate of what your own thyroid makes. Armour thyroid is ground up pig glands that are not standardized, not testable by routine lab and dangerous. ...Read more

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Why would my Synthroid (thyroxine) work for a couple months then stop working making me hypo where they have to up the med again?

If you're: Taking brand name T4 replacement and not missing doses, and not taking it at the same time as iron/calcium/vitamins -- then it doesn't change how it works. Perhaps your thyroid has changed, or you're taking unreliable generic replacement. ...Read more

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Does taking a higher dose of Synthroid (thyroxine) mean your thyroid is working even less? Like going from 150 to 200 mcg?

Possibly: For most people, a full replacement dose of Synthroid (thyroxine) would be 125 to 150 mcg daily. Once you are above 150 mcg, the more likely explanation is that you are not absorbing the drug well. You must take it on an empty stomach and wait at least 40 min. before eating. Don't take other meds, vitamins or supplements for a few hours. ...Read more

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Feeling dizzy when working out. Low energy and ambition. Had TSH elevated, fT3/4 normal. Should i start taking l-thyroxine or test for addison's first?

Feeling dizzy when working out. Low energy and ambition. Had TSH elevated, fT3/4 normal. Should i start taking l-thyroxine or test for addison's first?

Neither: If your TSH is only borderline elevated (5-10 range) and free T4 is normal you are very unlikely to feel better after starting l-thyroxine as fatigue is due to low free T4. Addison's disease is very rare and in addition to fatigue the symptoms which suggest it are weight loss, abdominal pain, salt craving and darkening of the skin. Your symptoms could be due to lots of non-medical issues. ...Read more

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Why when I take my Synthroid (thyroxine) thyroid medicine it makes me gain weight, I still be tired, cold I take iron pills, vitamin, do that surpose to happen, my medicine not working, doctor says I am find?

Why when I take my Synthroid (thyroxine) thyroid medicine it makes me gain weight, I still be tired, cold I take iron pills, vitamin, do that surpose to happen, my medicine not working, doctor says I am find?

Try another med: Some patients just don't respond well to basic thyroid replacement (like levothyroxine). Consider using an alternative like Armour Thyroid or tirosint. If your physician is uncomfortable with this, consider seeing an endocrinologist. ...Read more

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I just seen my synthroid expired 13 months ago. I have been useing it for sometime now. Will it still be effective I wonder or make me ill?

It will not be 100%: effective. Most prescription expiration dates are estimated to be two years from when it's manufactured. So if your Synthroid expired in March 2016, meaning it was manufactured in 2014. So in 2017, it may be only 50% effective. Since it's important to know if your synthroid is effectively treating your hypothyroidism, it's best to use Synthroid that's in date. ...Read more

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Each morning before I take my synthroid I feel very bad and about 1 hr after taking it feel good. Why is that? Does it wear off by the morning?

Possibly,..: Everyone metabolizes medications differently, and in your case, your symptoms are what they are, so it is possible the meds are waxing in the AM. Try talking to your Dr. and maybe taking the meds at Noon or even in the PM hours may help decrease the feeling you get in the AM. Best wishes. ...Read more

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Is 93bpm with thyroxine notmal or obermedicated?

Can't tell: 93 BPM refers to your heart rate. Under 100 is normal. You cannot assess thyroid levels by looking at heart rate. You should have thyroid blood tests of TSH and free T4 to see if you are on the correct dose. ...Read more

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What are the symptoms of underdose of thyroxine?

Hypothyroidism: When thyroid hormone is low people symptoms are highly variable from person to person. Some people do not have symptoms from mildly low thyroid hormone. Symptoms depend on degree of deficit and amount of time the hormone has been low. Here are some symptoms that are possible; fatigue, constipation, weight gain, cold intolerance and dry skin. ...Read more

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What could be the effects of taking too much synthroid (thyroxine)?

Being hyper: Too much synthroid (thyroxine) can make you feel hyper, cause diarrhea, weight loss, feeling hot or hot flashes, anxiety, poor sleep, heart pounding. Please speak with your doctor if you are having these symptoms. ...Read more

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Is thyroxine safe in pregnency?

Is thyroxine safe in pregnency?

Thyroid Treatment: Yes. Of course. And low or hypo thyroid in pregnancy is dangerous. Take you medication. ...Read more

Dr. Joseph Mathews
627 doctors shared insights

Synthroid (Definition)

Synthroid is a thyroid ...Read more