Doctor insights on:
Synthroid Affect On Liver
Raised Liver ALT&GGT, no history of being raised before - don't drink. Only new med is thyroxine. Bilrub, ALP, protein, albumin, globulin normal. Why raised?
How raised?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have been helpful to have the actual values. As a rule of thumb, it the values are more three times the normal limit, it is not an emergency and you may see your doctor at your convenience. ...Read more
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Yes: In a recent review of 85, 248 people taking synthroid (thyroxine) and reporting side effects, 210 of them reported enlarged liver (0.25%). It was noted to be more common in women than in men and was most common in the age group over 60. People with enlarged liver had been on synthroid (thyroxine) anywhere from 1 month to 2 years. ...Read more
I have non-alcoholic fatty liver and need to have my Thyroid Removed. Should I be taking Armour or Synthroid (thyroxine)?
I'm on bystolic (nebivolol). Synthroid and omeorazole daily. I got blood work and my liver enzymes were in range but still higher than normal. Ast-32 and alt- 42. Is it one of my meds?
Bystolic (nebivolol): Www. Epocrates. Com suggests monitoring lfts if you take bystolic (nebivolol) but there's no mention of this for either synthroid or omeprazole. With that said, non-alcoholic fatty liver is a consequence of being overweight/obese so if that describes you, that would be the better choice (rather than stopping bystolic (nebivolol)) since losing weight could then lower your blood pressure, too. Chat w/your prescribing doc. ...Read more
I'm on metoprolol, benicar, omeorazole, allegra, synthroid, (thyroxine) and ativan. Will any of these cause liver kidney or electrolyte issues? Or cardiac issues?
Unlikely: I guess the answer depends on whether you are a glass half empty or a glass half full person. You are not likely to have any of those adverse effects from the medications you listed, however there is no medication that is not associated with rare liver toxicity, and several of the medications on the list might have some of the other side effects you listed. Rarely. ...Read more
Can these meds cause ^ liver enzyme? Synthroid losartan prednisone Paxil (paroxetine) Xanax calcitriol calcium citrate amox-clav singulair advair, and multivit
Last night I had painful cramps in lower abdomen. The pain seemed to move with my bowel movement but stopped once I pooped. I take 75mcg Synthroid (thyroxine) daily?
Hypothyroid: Hi. If you're hypothyroid and don't take your l-thyroxine, you'll be untreated hypothyroid...but somehow, I betcha knew that! ...Read more
Possible: Levothyroxine (t4) has a long 1/2 life (up to 10 days in new hypothyroidism) so it is possible to dose a higher dose less often (e.g. 100mcg every other day). The problem we run into is compliance issues: many patients tend to forget to take their pills unless it is given once daily. ...Read more
Abusing meds: No. The opposite would happen.Get a more detailed answer ›
I'm on 100mc Synthroid (thyroxine) my th levels are normal but it seems I still can't make it through the day?
Define normal: There is a lot of controversy about what exactly constitutes "normal" thyroid labs. If the TSH is between 0.5 and 2.5, I agree that it is time to look for for other causes. If above or below this, adjusting the thyroid dose to tweak the TSH into this range may improve your symptoms. ...Read more
My dr priscribed me 37.5mcg thyroxine dose. I don't want cut 75mcgpill so can I take 75mcg pill every second day for same result?
Yes: Thyroid hormone has a very long "half-life". It will make no difference taking 75 mcg very other day vs 1/2 pill every day. However, a dose of 37.5 mcg daily is a very small dose for someone in your age group. If 75 mcg was too high a dose, you could be on 50 mcg as the next step down. ...Read more
Fnp wants to raise my Synthroid (thyroxine) from 50 mcg to 75. I don't understand the mechanics behind this medicine. Can you explain?
TSH: Hi. Your FNP probably tested your TSH and found it to be high on your current dose of 50 mcg/day. TSH is the pituitary hormone that reflects thyroid status (assuming normal pituitary function); if TSH is hi, your pituitary is trying to push your thyroid to make more thyroid hormone, but your thyroid is damaged and can't. Therefore, you give more Synthroid (thyroxine) until the TSH is down in the normal range ...Read more
My dr priscribed me 37.5mcg thyroxine but I can't cut 75mcg pill equal so can I take 75mcg pill every other day for same result it is right?
75 every day should be OK.
When you get your next meds from your pharmacy make sure there is a line down the middle of the pill that makes it easy to break (not cut) in two. ...Read more
I haven't taken my Synthroid (thyroxine) in about a month. Since that month I have gained 25lbs. Is it because I'm off my synthroid (thyroxine)?
Probably two reasons: If you have been prescribed synthroid or levothyroxine replacement therapy, then your body likely needs thyroid hormone therapy to maintain normal thyroid levels. When you stop synthroid, and the thyroid levels become very low, you can then gain weight from two major factors: fluid retention, and slowed metabolism. Please check with your doctor to discuss what dose of synthroid you should restart. ...Read more
I started synthroid (thyroxine) 25 mcg 2.5 wks ago for hypo. The last few days, I've felt very full (almost sick) when I don't eat much. Is this related? Why?
Very unlikely: Synthroid is giving you levothyroxine, a naturally occurring compound that the thyroid normally makes. It is remotely possible (< 1% chance) that the headache could be due to a reaction to the dye in the pills. If so, then switching to 50 mcg pills (may need more than 1 per day) would eliminate the headaches. ...Read more
If I have been using Synthroid (thyroxine) for years and it isn't working, should I ask about armour or something not synthetic?
There is: No such thing as Synthroid (thyroxine) "not working". If you take the proper dose to keep your levels normal, it's working. If you have other problems, they are not due to your hypothyroidism. Synthroid (thyroxine) is an exact duplicate of what your own thyroid makes. Armour thyroid is ground up pig glands that are not standardized, not testable by routine lab and dangerous. ...Read more
I am taking Synthroid (thyroxine) 25 mg. I have been loosing weight. I don't think this dosage is high enough. And why am I loosing weight.
I switched to Synthroid from levothyroxine but I can't afford the Synthroid & ever since I've had hbp spikes is it safe to switch back to levothyroxine?
Yes: It is safe. A simple blood test to check your thyroid function should confirm if the generic is providing adequate thyroid replacement. ...Read more
Insulin is digested: Thyroxine is a small molecule similar to an aminoacid and it gets absorbed intact from the gut. When circulating it then behaves like naturally produced thyroxine. Insulin is a protein digested/broken down into dipeptides and aminoacids. Obviously once broken down and absorbed into the bloodstream it no longer exists as the intact molecule which is needed for its hormonal function. ...Read more
Hyperthyroidism: If you are hyperthyroid, it will cause symptoms; common ones are heat intolerance, palpitations, nervousness, tremor, diarrhea, irritability. It causes bone loss (osteoporosis) over time. It places a stress on your heart, which may be tolerated when young, but not with aging. It can be treated, but you may need to see an endocrinologist. ...Read more
Yes: Generic synthroid is called levothyroxine. Taking generic version is reasonable and will likely achivevsimilar results, however I would recommend that you inform your endocrinologist about such switch as you may need to have your thyroid levels checked soon (a few weeks) after making the switch to ensure your dosing is appropriate. I would also recommend that you adhere to one kind of preparation. ...Read more
See below.: Thyroxine overdose can cause tremors, anxiety, increased heart rate, increased body temperature, agitation, confusion, diarrhea, and seizures. If you are ever worried that an overdose has occurred, call 911. If you’re less certain and feel the situation is less of an emergency, call 800.222.1222 for guidance. ...Read more
Hypothyroidism: When thyroid hormone is low people symptoms are highly variable from person to person. Some people do not have symptoms from mildly low thyroid hormone. Symptoms depend on degree of deficit and amount of time the hormone has been low. Here are some symptoms that are possible; fatigue, constipation, weight gain, cold intolerance and dry skin. ...Read more
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