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Doctor insights on: Syndrome X Fragile

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Dr. James Ferguson Dr. Ferguson
Pediatrics
42 years in practice
University of Texas Medical Branch School of Medicine
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Need to know about fragile x syndrome? What is fragile x syndrom?

Need to know about fragile x syndrome? What is fragile x syndrom?

Male dominated: The fragile x is named for a non staining region on the long arm of an x containing useless genetic material that results in mental impairment & physical changes(if you only have 1 x:males).The females usually show few if any features due to protection by a normal x, but not always & have a 50% chance of passing the fragile x to any offspring. This is a male dominated form of mental impair ...Read more

Dr. Thomas Namey Dr. Namey
Internal Medicine - Rheumatology
44 years in practice
Washington University School of Medicine
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What are the tests for syndrome x (cardiac)?

What are the tests for syndrome x (cardiac)?

Many.: You need to look at and control lipids and hbp. First, most have an apple build, ie. Carry weight on the torso, rather than buttocks and extremities. Family hx of hbp, cholesterol problems, diabetes 2, and ASHD or mi, especially if strong. I obtain fasting lipids, insulin, hgba1c. A lipid profile suggesting syndrome x is high triglycerides and low hdl. Ldl may be low becasue of high tgs. ...Read more

Dr. Thomas Namey Dr. Namey
Internal Medicine - Rheumatology
44 years in practice
Washington University School of Medicine
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What are the tests for syndrome x (metabolic)?

What are the tests for syndrome x (metabolic)?

Many. Family Hx 1st.: First, most have an apple build, ie. Carry weight on the torso, rather than buttocks and extremities. Family hx of hbp, cholesterol problems, diabetes 2, and ASHD or mi, especially if strong. I obtain fasting lipids, insulin, hgba1c, and in females, free and total testosterone. The latter, since pcos is common. A lipid profile that suggests Insulin resistance is high triglycerides and low hdl. ...Read more

Dr. Jovita Anyanwu Dr. Anyanwu
Internal Medicine
26 years in practice
Lyceum Northwestern, Dr. Francisco Q. Duque Medical Foundation
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I have been diagnosed with dysmetabolic syndrome x - what is the absolute best diet to be on - i cannot lose weight! help!

I have been diagnosed with dysmetabolic syndrome x - what is the absolute best diet to be on - i cannot lose weight! help!

Reduce calories: See a bariatrician. Frequent small meals, low glycemic index carbs, lean meat, lots of veges and sometimes apetite suppresses and management psychological/mental health issues. ...Read more

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Dr. Bennett Werner Dr. Werner
Internal Medicine - Cardiology
40 years in practice
University of Maryland School of Medicine
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I was diagnosed with dysmetabolic syndrome x and am still having problems losing weight - what kind of diet/food is best? Help!

I was diagnosed with dysmetabolic syndrome x and am still having problems losing weight - what kind of diet/food is best?  Help!

Difficult: I have the same problem. So do 100 million americans. You are not alone. Here's a link that can give you some guidance but there's no easy solution. http://www.mayoclinic.com/health/mayo-clinic-diet/my01646. ...Read more

Dr. Alan Feldman Dr. Feldman
Internal Medicine - Endocrinology
37 years in practice
Pennsylvania State University College of Medicine
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How can I beat syndrome x (insulin resistance) through diet?

How can I beat syndrome x (insulin resistance) through diet?

Low carbs: The most successful diet for people with insulin resistance is low carb/low starch diet (South Beach, Zone diet). Any diet that promotes weight loss will help lower insulin resistance. Exercise is also essential to help lose weight and keep it off. ...Read more

Dr. Philip Kern Dr. Kern
Internal Medicine - Endocrinology
39 years in practice
New York Medical College
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Can i tell me how i can beat syndrome x (insulin resistance) through diet?

Can i tell me how i can beat syndrome x (insulin resistance) through diet?

Diet and exercise: Some of this is genetic, but you can minimize the genetics with diet, aimed at keeping your weight down, and exericise, as much as you can. ...Read more

Dr. Richard Roberts Dr. Roberts
Clinical Genetics
42 years in practice
Southern Illinois University School of Medicine
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Can you tell me if I am a carrier of fragile x will my son have higher chances of down syndrome?

Can you tell me if I am a carrier of fragile x will my son have higher chances of down syndrome?

No, risk of both: If you or dad have a blood relative with Down, your risk at delivery is 1%. if none, at 37 the risk at term is 1/226, and before 14 weeks 1/52 (many affected die before term). Risk for a male with Fragile X is ½ males, and for a carrier female, ½ females. You may have CVS to determine both. If termination is not an option, you may have preimplantation diagnosis for both, or a donor egg. ...Read more

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Dr. Steven Neish Dr. Neish
Pediatrics - Cardiology
34 years in practice
Sanford School of Medicine of the University of South Dakota
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Can you tell me what you suggest if you are a carrier of fragile x, will your son have higher chances of down syndrome?

Can you tell me what you suggest if you are a carrier of fragile x, will your son have higher chances of down syndrome?

Unrelated: Fragile x and down syndrome are unrelated conditions. Down syndrome is due to an extra copy of chromosome 21, most typically trisomy 21. Most cases of fragile x are due to a mutation of the fmr1 gene which is located on the x chromosome. ...Read more

Dr. Mathew Chengot Dr. Chengot
Internal Medicine - Cardiology
39 years in practice
University of Kerala, Kottayam Medical College
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What is the difference between kounis syndrome and syndrome x? Is there a test to diagnose?

What is the difference between kounis syndrome and syndrome x?  Is there a test to diagnose?

Different: Knunis syndrome can cause angina heart attack from coronary hypersensitivity and allergic reaction metabolic syndrome is a group of group of risk factors that occur together that increases the risk of cad. Strolke and diabetes. ...Read more

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Dr. Stephen Southard Dr. Southard
Internal Medicine
11 years in practice
Tufts University School of Medicine
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What is the best exercise for cardiac syndrome X?- my CSX doesn't seem to be affected by exercise, I feel it's worse at rest.

What is the best exercise for cardiac syndrome X?- my CSX doesn't seem to be affected by exercise, I feel it's worse at rest.

No clear answer: The best exercise is the type that does not induce symptoms and one that you'll consistently complete. Otherwise, there really is no evidence that any particular form of exercise is better for those with cardiac syndrome X. Any form of exercise is good for vascular health and may help with some elements of "visceral hypersensitivity" - as in sensitivity to "inside body" pain. ...Read more

Dr. William Goldie Dr. Goldie
Pediatrics - Neurology
44 years in practice
UC San Diego School of Medicine
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What is fragile x syndrome?

What is fragile x syndrome?

Defective chromosome: Each person has 23 pair of chromosomes. Males have xy and females xx. Some persons have a defective x with a portion that is missing. In females the other x compensates and they have no clinical problems. In males the defective x can result in retardation and/or autism. Some with defect can be normal but transfer problems to their sons. ...Read more

Dr. Cornelia Franz Dr. Franz
Pediatrics
years in practice
Wake Forest University School of Medicine
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What is a fragile x syndrome?

Genetic problem: Fragile x syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females. http://ghr.nlm.nih.gov/condition/fragile-x-syndrome. ...Read more

Dr. William Goldie Dr. Goldie
Pediatrics - Neurology
44 years in practice
UC San Diego School of Medicine
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What causes fragile x syndrome?

Chromosome defect: Patients with fragile x have a defective x chromosome. There are several variants, and not all cells may be affected. It is full disease only in males, but females can be carriers. It is a genetic disorder, but it often just occurs without warning. Affected boys can vary from normal to severe retardation and autism. There is no cure. ...Read more

Dr. Darren Gitelman Dr. Gitelman
Neurology
32 years in practice
Washington University School of Medicine
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What causes of fragile x syndrome?

What causes of fragile x syndrome?

Gene mutation: Fragile x syndrome is due to a mutation within the fmr1 gene on x chromosome. Part of the gene gets repeated too many times. It is the most common genetic cause of intellectual disability. Please see: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0002633/ and http://www.Fragilex.Org/ for more information. ...Read more

Dr. Jay Park Dr. Park
Pediatrics
46 years in practice
Yonsei University College of Medicine
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How prevalent is fragile x syndrome?

How prevalent is fragile x syndrome?

See below: Fragile x syndrome is the most frequent form of inherited intellectual disability. The prevalence in men runs from 1 in 4, 000 to 1 in 6.000. The prevalence in women is estimated at 1 in 10.000. ...Read more

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Dr. Josephine Ruiz-Healy Dr. Ruiz-Healy
Pediatrics
35 years in practice
University of Anahuac School of Medicine
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Whats the cause of fragile x syndrome?

Whats the cause of fragile x syndrome?

Genetic: Fragile x is caused by just one defective gene. This gene also known as fmr1, shuts it self down and fails to produce a protein. The incidence is 1 in 4000 males and 1 in 6-8000 females have it is the most common cause of inherited mental disability-. ...Read more

Dr. Michelle Karten Dr. Karten
Pediatrics
18 years in practice
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School
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Fragile x syndrome my baby, what to do?

Fragile x syndrome my baby, what to do?

Developmental help: Fragile X syndrome can predispose your baby to developmental and learning issues. It is important to have your baby evaluated by Early Intervention, a program to support infants with delays. Call your doctor to get this information. ...Read more

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Dr. James Ferguson Dr. Ferguson
Pediatrics
42 years in practice
University of Texas Medical Branch School of Medicine
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How common is fragile x syndrome in us?

How common is fragile x syndrome in us?

Depends on your dfn: Significant impairment (iq<70) in FAS is felt to represent 1/3600 of the population, mostly male. A lesser form of involvement with lesser alterations in this gene (add, behavior issues) may affect 1/130-250 female & 1/250-800 males. See: www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc2888470/?Tool=pmcentrez. ...Read more

Dr. Troy Reyna Dr. Reyna
Surgery - Pediatric
40 years in practice
Georgetown University School of Medicine
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