Doctor insights on:
Synarel Gnrh Stimulator
FSH,LH: Gnrh stimulates follicle stimulating hormone & luteinizing hormone which stimulates the ovary to produce estrogen and Progesterone which stimulates ovulation which causes increased Progesterone which causes secretory endometrium which prepares the endometrium to allow implantation of a fertilized egg. If no fertilized egg, Progesterone falls which stimulates gnrh to again rise & the cycle repeats. ...Read more
Unlikely: Generally no, not pain unless you mean pain at the injection site. ...Read more
Good question: Gnrh would seem by its name to help release gonadotropin. And if used in a certain fashion it could cause the release of gonadotropins (lh, fsh). However when given in a shot and having a sustained effect on the pituitary, it actually suppresses the release of lh and fsh. And this aspect of the medication can be used to help in many situations. ...Read more
Unclear Question?: These are somewhat unrelated questions which makes it difficult for me to address your question. Evista (raloxifene) is not used for treating cancer...It is sued for treatment/prevention of osteoporosis. Estrogen receptors are specialised protein receptors found in breast cancer.Uterine cancer has little bearing on either of the two references you have listed. ...Read more
Her how it works: The g protein-coupled, seven-pass transmembrane molecule present in the parathyroid gland and kidney controls calcium homeostasis by releasing parathyroid hormone (pth). Manipulating calcium-sensing receptor (casr) using small-molecule allosteric modulators can affect PTH secretion. ...Read more
Are gonadotropic hormones only glycoproteins (fsh, lh)? Sex steroids would be classified as steroids, separate from gonadotropins, right?
Right: I'm glad you are learning the differences among the classes of biomolecules. ...Read more
Chemical menopause: Zoladex (goserelin) 3.6 mg implanted every 28 days will put a woman chemically into menopause and make her menstrual periods stop. In fact, about 2 weeks after the first implant there will be a hormone withdrawal bleeding, after the next implant there will be no bleeding, if the medication works perfectly. ...Read more
Endometriosis ...: Depo-lupron monthly or 3-month injections are used for women with endometriosis or chronic pelvic pain, men with prostate cancer, and children with puberty too young. It may be used to shrink uterine fibroids before surgery. Depo-lupron is used in fertility treatment to prevent ovulation in frozen embryo transfer cycles & egg donor recipients, and can be used before ivf in women with endometriosis. ...Read more
Clomid (clomiphene) is an estro receptor.Brain needs estrogen surge to release lh.Which means ppl on Clomid (clomiphene) don't have LH surge?How egg burst out?
Got confused?: You are getting yourself confused. Clomid (clomiphene) is not an 'estro receptor' at all; it is mainly an estrogen receptor antagonist, but it has pro-estrogenic actions in some tissues and anti-estrogenic actions in others. Women on Clomiphene do mostly have an lh surge; not surging means the Clomiphene dose was likely too low. ...Read more
REALLY unusual: I doubt it, it would be truly unusual. ...Read more
Can patient undergo ovulation induction using gonal f (follitropin alfa) while using HRT mainly femoston 2/10 mg?
Doesn't make sense: In most cases this would not make much sense, although it could depend on 'why' and 'how' the hrt was being used. Estrogens such as in hrt are sometimes used in stimulation protocols with gonadotropins (such as gonal f, (follitropin alfa) ) an oral progestin would be an unlikely element of most protocols. ...Read more
Aromatase: FTM requires two things: 1: I do not take care of such patients unless I am notified by a Psychologist who is taking care of the patient. 2: I do not see any indication for aromatase inhibitors to be given in addition to testosterone. I have been fortunate to have reasonable success with FTM and MTF. ...Read more