Doctor insights on:
Symptoms Of Xeroderma
What is the relation between the nature and symptoms of xeroderma pigmentosum and ataxia telangiectasia ?
Deficiency in some : part of cell mechanisms that detect & repair damage to DNA molecules that encode their genome occur in 5 inherited diseases: ataxia-telangiectasia (AT), Fanconi anemia, Bloom syndrome, Cockayne syndrome & Xeroderma Pigmentosum (XP).7 different mutant repair genes cause XP; types A, C, D & E are on Chromosome 9q.22. Mutations in ATM genes cause AT. Groups A,C,D & E are on Chromosome 11q2. ...Read more
Genetic Testing: There are several types of xp (xeroderma pigmentosa) all of which are related to genetic defects in the ability of cells to repair dna damage causes by uv (ultraviolet rays). Xp dramatically increases your risk for skin cancer. You should start with seeing a dermatologist and go from there. If there is suspicion you may have the disease, genetic testing will be required to confirm this. ...Read more
Xeroderma pigmentosu: Xeroderma pigmentosum is a condition which makes people very sensitive to the sun (uv rays). It can cause severe sun burning & freckling of skin. It is called xeroderma because it can dry the skin out and pigmentosum because there is added skin pigment. It can affect the eyes and may be associated with a number of other symptoms. ...Read more
Careful observation: This congenital condition requires sun avoidance and very close observation by an experienced dermatologist and/or plastic surgeon. Suspicious lession must be monitored and biopsies are essential to rule out malignancy. ...Read more