Doctor insights on:
Symptoms Of Mixed Connective Tissue Disease
Joint, skin, interna: Mctd can have a variety of signs and sympotms whichcan change with times. By the name it is a mixture of a variety of connective tissue diseases: systemic lupus erythematosus, scleroderma, polymyositis and rheumatoid arthritis. Depending on which condition is prominent at the time. When you are evaluated your physician will look for causes of the symptoms from these categories. ...Read more
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
I display all symptoms of mixed connective tissue disease but ANA tests were only slightly above average. Can this still be what i have?
Ever since symptoms of my undifferent connective tissue disease started, i get indescribable exhaustion very easily despite good sleep & normal labs. Why?
Undifferentiated connective tissue disease.Methotrexate was very effective controlling symptoms but not tolerated due to side effects.Other options?
If you have positive cryofibrinogen with symptoms and a history of connective tissue disease, when is it advisable to get opinion of a hematologist? What types of tests would the hematologist run?
A lot: Most hematologists like to run a battery of tests. You want to have a very good insurance for these expensive tests. You may even want a second or third opinion to know if it is necessary to obtain all these tests. You may need a little bit of Prednisone or you may really need a lot of tests. Therefore try to obtain additional opinions. ...Read moreSee 1 more doctor answer
Is an ANA of 1:640 (multiple times) significant if many of the symptoms of a connective tissue disease are there but other bloodwork including specific antibodies are negative?
Probably, but note,: Diagnosis of lupus depends on presence of at least 4 criteria from a multitude of criteria not just symptoms. Examples include arthritis, ana, low white or red blood count, pleurisy, confusion, rash, etc. Some of the criteria may occasionally have different reasons other than lupus. Your doctor can address with you what criteria you may actually have that count towards lupus. ...Read moreSee 1 more doctor answer
Rheum treats me 4 unspecif connective tissue disease.Many symptoms & homogen ANA 1:640.All other labs neg.If having sx, why are other labs neg?Frustrating.
More info needed: What are your symptoms? What is your sed rate? From the information given it looks like the doctor is treating the lab work and not the patient. ...Read more
Lupus like symptoms resolved on Methotrexate.Current diagnosis in chart is undifferentiated connective tissue disease.My rheumMD say we dont have name yet.Unusual?
Actually: This is very common... Until symptoms are more typical and laboratory tests are confirmatory ...Read more
Do rheumatologists commonly see undiff connective tissue disease patients with lots of ctd symptoms but normal labs (other than high ana)?
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