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Doctor insights on: Symptoms Of Infiltrating Ductal Carcinoma

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What causes ductal carcinoma in situ (dcis)?

What causes ductal carcinoma in situ (dcis)?

Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more

Dr. Barry Rosen
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Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Bryan Wu Dr. Wu
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What's the chromosome number of infiltrating ductal carcinoma?

Dr. Bryan Wu Dr. Wu
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What's the chromosome number of infiltrating ductal carcinoma?

Depends on grade: The level of chromosomal aberrations in infiltrating ductal carcinoma is correlated with the grade of the cancer cells. "grade" means the microscopic appearance and corresponds with how closely the cancer cells try to form normal breast structures. High grade or poorly differentiated infiltrating ductal carcinomas tend to have more chromosomal abnormalities than non-high grade carcinomas. ...Read more

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Symptoms of pancreatic cancer?

Symptoms of pancreatic cancer?

Depends on location: Pancreas is a fish-shaped organ with its head tucked into the duodenum (c-shaped beginning of small intestine coming off stomach). If tumor blocks bile duct or panc duct, causes abdominal pain, pancreatitis, jaundice. If it's in tail, will cause no symtptoms till very large or spread to other areas. Most common: weight loss, mental status change such as new onset depression. ...Read more

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Symptoms of pancreatic cancer?

Symptoms of pancreatic cancer?

Highly variable: Each person is different. Much of the early stage of pancreas cancer has no symptoms. May have gradual onset of lack or appetite and gradual weight loss. Later posdible yellow jaunduce formation. Later stage pancreas cancer can cause a severe boring pain from the mid upper abdomen into the upper back. ...Read more

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Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www.webmd.com/cancer/carcinoid-tumors#1 ...Read more

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Symptoms of liver cancer?

Symptoms of liver cancer?

None: Primary liver cancer, hepatocellular carcinoma (hcc), has no symptoms early on. But most cases of hcc are associated with cirrhosis, the symptoms and signs of which include jaundice, muscle wasting, hepatosplenomegaly, variceal gasteointestinal bleeding, encephalopathy and the development of ascites. Pts with cirrhosis should be screened every 6 mo for hcc with a liver us and an AFP check. ...Read more

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Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Yes: Adenocarcinoma in situ is cancer. The area suggestive of micro invasion suggests you should have rather aggressive followup screening which I am sure your doctor has, or will soon suggest. Stay on top of this and follow his/her advice. ...Read more

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Dr. James Lin Dr. Lin
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What are signs of hepatocellular carcinoma?

Dr. James Lin Dr. Lin
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What are signs of hepatocellular carcinoma?

No...: In its early stage, the patient virtually has no symptoms at all. The key to its diagnosis is still professional alertness notably for someone with hepatitis - b, -c, liver cirrhosis, chronic alcohol use, with known abnormal finding in liver function test. These patients are advised to have periodic follow-up with blood tests and liver ultrasound study. Any doubt, see an expert timely. Best. ...Read more

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What percentage of atypical hyperplasia becomes breast cancer?

What percentage of atypical hyperplasia becomes breast cancer?

Small percentage: In a recent study in the annals of surgical oncology, they looked at how many surgical excisions performed for atypical hyperplasia displayed either dcis or cancer. Out of the cases that the study reviewed, only about 1% of the cases upstaged to either dcis or cancer. ...Read more

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Fragments of hyperplastic squamous epithelium with basal zone hyperplasia. Underlying stroma moderate infiltrate of chronic inflammatory cells. Bad?

Fragments of hyperplastic squamous epithelium with basal zone hyperplasia. Underlying stroma moderate infiltrate of chronic inflammatory cells. Bad?

Not cancer: Nothing in this dscription says 'cancer'. In fact, nothing in this description says it's other than just a palce where you scratched for a week or so because it itched. The key is the clinical correlation. ...Read more

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Grade 2 invasive ductal carcinoma infiltrating as cords and tumour cells in a fibroadipose stroma, what does this mean?

Grade 2: There are 2 basic forms of breast cancer, ductal and lobular. Yours tumor is a ductal but it sounds like it has some lobular features, in particular it's infiltrating as cords sometimes called "Indian file infiltration". I don't think this has any clinical significance. See your oncologist and follow their advice. Most important is knowing lymph node status. Best of luck and God bless. ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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How are carcinoma in situ and benign neoplasm different?

Good question: And difficult to tell sometimes. The most straightforward way to put it is that a benign neoplasm will never turn into an invasive malignancy within your lifetime. Cis will eventually turn into one. But, because we don't live forever, cis might not turn into a malignancy during one's lifetime anyway. Pathologists can usually, but not always, tell the difference by microscopic cell exam. ...Read more

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Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?

Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma.  What does this means.?

Needs treatment: Means you have cancer of oral cavity ( buccal mucosa ) from your description appear to be localised you will have good prognosis needs further work up for staging &care , by surgical excision for localized small area, or chemo radiation , discuss with your physicians and please do not delay . Good luck. ...Read more

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Describe the features of bronchogenic carcinoma.?

Describe the features of bronchogenic carcinoma.?

Widely varied: Most lung cancer causes no symptoms. Symptomatic cancer is less likely to be curable. Symptoms include; cough (with or without blood), chest pain, shortness of breath. To make it more confusing, the vast majority of people with these symptoms don"t have cancer. Rarely symptoms come from when the tumor produces a hormone that causes symptoms, or antibodies against the tumor cause symptoms. ...Read more

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What are the symptoms of hepatocellular carcinoma?

What are the symptoms of hepatocellular carcinoma?

Often asymptomatic: Since the liver is so resilient, hcc can be asymptomatic until late stages. When symptoms are present they will manifest as nausea, taste disturbances, fatigue and sometimes jaundice. ...Read more

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