Doctor insights on:
Symptoms Of Factor V Deficiency
I got my results back from Factor V deficiency and it says Interpretation 77% what does this mean?
Factor V %: This measures how functional your ativated protein C is - APC degrades Factor V. 2 tests are run - one with and 1 without APC and the ratio shows how much activity there is. Important since the Factor V mutation products a variant of Factor V that isn't degraded by APC. Talk with your hematologist. ...Read more
Deficiency or factor: V Leiden?. Since you are on coumadin, (warfarin) it is not likely that you are deficient in Factor V but have an abnormal factor V that makes you susceptible to blood clots. The only cure for congenital factor V deficiency or Factor V Leiden would be liver transplant, but this treatment is likely to be worse than the disease. ...Read more
I found out I have Factor V Deficiency. My mother has Factor V leiden. What is the difference between those?
Huge difference: Factor V deficiency of a clotting factor which can result in a hemophilia like illness with excessive bleeding. On the other hand Factor V Leiden refers to a mutation which increases the risk of clotting and thrombosis. The distinction is very important. Women with Factor V Leiden should not take hormonal contraception. Please clarify your diagnosis with your physician as soon as possible! ...Read more
I just got diagnosis w/Factor V deficiency. Was on cryselle Birth Control. What else can I take for birth control methods with this disorder?
Avoid estrogen.: You may take progestin-only or non-hormonal contraceptives, eg copper IUD. Depo Provera (medroxyprogesterone) is progestin only, but in studies, it has increased the risk of blood clot in FVL deficiency. Cryselle contains estrogen, which, when taken by a patient with Factor V Leiden deficiency, can increase the risk of blood clot. I would also come off the Seasonale; this has estrogen in it. Hope this helps! ...Read moreSee 1 more doctor answer
I am in Coumadin, (warfarin) factor V deficiency, twice DVT after sprained ankles, PCOS. Can I start an HCG weight loss program?
I have factor v leiden deficiency and take 20mg warfarin daily. Can i take ace?(it's a appetite suppressant)
Does leiden factor v have any symptoms when not pregnant? What can be associated with this? (blood pressure or something?) thanks
Blood clots : Factor v leiden is an inherited mutation that is associated with modest increase in the risk of blood clots if you have one copy of the mutation and high if you have 2 copies. Most people have one copy (heterozygous). If a blood clot develops, you need a course of blood thinner. If never had a blood clot, i recommend using preventive blood thinner in high risk situation (surgery, long trip, etc). ...Read more
Pls. clarify: Do you mean factor v deficiency? Someone with this deficiency and had blood clots would likely be prescribed a blood thinner for lifetime. If there is a life-threatening blood clot, they may receive a tranfusion of plasma (blood liquid). Plasma does not last long in the body. ...Read more
Thrombosis: People who inherit the leiden variant of coagulation factor v are at incresed risk of venous thrombosis. Those who are heterozygotes their risk is 5-10 fold higher, homozygotes are about 50 fold greater risk. Women on birth contol pills are partiuclarly susceptible to thrombosis if they have leiden factor v. If the affected individual develops thromobsis, life long anti-coagulation may be needed. ...Read more
Risk for blood clots: People homozygous for factor v leiden are about 50 times more at risk of developing blood clots in their veins and complications related to that. See this site for more info. http://www.mayoclinic.org/diseases-conditions/factor-v-leiden/basics/definition/con-20032637. ...Read more
Yes: Factor v leiden is a genetic condition. If you have one copy of a fvl mutation, you are heterozygous with an increased risk of blood clotting. If you have 2 copies you are homozygous with an even higher risk of clotting. The inheritence pattern is simple mendelian genetics. You get one copy of the gene from your mother and one from your father. ...Read moreSee 1 more doctor answer
Yes: I'm going to assume that you have factor V Leiden, that makes your blood more clott-able. I'd be more worried making sure that your oral contraceptive pill is the right choice. You're very wise to accept medication for depression. It is likely that this, and some training in living skills and help with life circumstances, will greatly help the environmental allergies. Be brave & best wishes. ...Read more
Varies: There is actually no treatment for factor v leiden. It is inherited and increases one's risk of a blood clot. Treatment is given either for a blood clot or for the prevention of a blood clot in certain circumstances, for instance during surgery or during pregnancy. Treatment is individual and depends on a number of factors that you would want to discuss with your doctor depending on the situation. ...Read more
Non-hormone methods: People with abnormalities of factor v are at increased risk of blood clots in the veins. For that reason we avoid birth control with estrogen in it (pills, patch, ring). Some doctors also avoid Progesterone (mirena (levonorgestrel) iud, implanon, pills, Depo-Provera provera) although the evidence on that is not clear. Barriers like condoms, cervical caps, and diaphragms are safe. So is the paragard iud. ...Read more
LARC methods: Estrogen containing contraceptives are contraindicated in women with FACTOR V LEIDEN DEFICIENCY. However evidence supports the safe use of progestin only contraceptives - LNG IUD(Mirena (levonorgestrel) or Skyla), Implant (Nexplanon), DMPA, POPs, or the nonhormomal copper IUD (Paragard). Barrier methods are obviously safe but less effective. ...Read more
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