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Doctor insights on: Switching From Zyprexa To Abilify

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Olanzapine (Definition)

Also called zyprexa, (olanzapine) is a second generation antipsychotic that works to alleviate symptoms of ...Read more


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Will Abilify (aripiprazole) cause insomnia if I take it? I thinking of making the switch over from zyprexa because of weight gain. Does it also cause akathisia?

Possibly: Although zyprexa is more notorious for causing weight gain than abilify, (aripiprazole) the switch might not provide much relief from this adverse effect. Abilify (aripiprazole) can cause increased appetite and weight gain, too. Abilify (aripiprazole) is as likely to cause sedation and drowsiness as it is to cause insomnia. I cannot predict the predominant effect which may prevail if you take it. Akathisia may result from Abilify (aripiprazole) as well. ...Read more

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I was taking zyprexa for 1 year.6 months after I stopped it had a 2nd maniac episode. Now I am taking Abilify (aripiprazole) for a year. Can I cut it without a 3rd ep.?

I was taking zyprexa for 1 year.6 months after I stopped it had a 2nd maniac episode. Now I am taking Abilify (aripiprazole) for a year. Can I cut it without a 3rd ep.?

Please don't: These meds are very critical never to stop as it will bring manic episodes if u understand how they work they help your brain to regulate the sda all three neuro transmitters to help u regulate your brain function so stopping the meds suddenly will collapse the system if u want to stop or change the meds talk to your doctor I do it all the time for my pts I know taking meds is hard but please dont. ...Read more

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Is it not a good idea to take zyprexa and Abilify (aripiprazole) together? Trying to decide if Abilify (aripiprazole) is better for me. Took it in the afternoon, zyprexa last night

Is it not a good idea to take zyprexa and Abilify (aripiprazole) together? Trying to decide if Abilify (aripiprazole) is better for me. Took it in the afternoon, zyprexa last night

2 Antipsychotics: Why are you taking 2 antipsychotics at the same time? This sounds like unusual prescribing -- and I suggest consulting with a psychiatrist for diagnosis and also appropriate treatment. If this is your psychiatrist prescribing 2 antipsychotics, please make sure s/he is not cross-tapering off of one with the intent of changing to the other. Taking both would be for a very brief time only. ...Read more

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Would Abilify (aripiprazole) cause more akathisia than zyprexa? I heard Abilify (aripiprazole) makes people wake up early. I need to wake up early for class. Zyprexa sleeps toomuch

Would Abilify (aripiprazole) cause more akathisia than zyprexa? I heard Abilify (aripiprazole) makes people wake up early. I need to wake up early for class. Zyprexa sleeps toomuch

Akathesia is a: Fairly common side effect from abilify (aripiprazole). Luckily it can be treated with medications like Cogentin or benadryl. No promises of waking up early on either medication but most of my patients sleep well on Abilify (aripiprazole) and are not groggy in the morning. ...Read more

Dr. Andrew Ho Dr. Ho
3 doctors agreed:
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Pdoc said Abilify (aripiprazole) is more "activating" than Zyprexa. At 30mg I am tired all the time. Is this due to Abilify (aripiprazole) or perhaps just stress from end of term?

Dr. Andrew Ho Dr. Ho
3 doctors agreed:
Pdoc said Abilify (aripiprazole) is more "activating" than Zyprexa. At 30mg I am tired all the time. Is this due to Abilify (aripiprazole) or perhaps just stress from end of term?

Differences: Between "general" response and specific individual response must be considered. Each person is different. Not everyone gets activated on Abilify (aripiprazole). You need to let your doctor know so he/she can recommend next step for you accordingly. ...Read more

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Will Abilify (aripiprazole) or zyprexa cause more akathisia? Inner restlessness? I feel both but think it is mainly abilify (aripiprazole).

Will Abilify (aripiprazole) or zyprexa cause more akathisia? Inner restlessness? I feel both but think it is mainly abilify (aripiprazole).

About the same.: Both Abilify (aripiprazole) and zyprexa can cause akathisia and inner restlessness. In my practice, more people seem to have more akathisia with Abilify (aripiprazole) although in both drugs, they are dose dependent. ...Read more

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I am diabetic refuse to use seroquil or zyprexa abilify. Dr started mr on 20 latuda (lurasidone). is this a good choice or basically the same old same old?

I am diabetic refuse to use seroquil or zyprexa abilify. Dr started mr on 20 latuda (lurasidone). is this a good choice or basically the same old same old?

Could be: Latuda (lurasidone) is a relatively new medication that is often used in treating bipolar disorder or in augmenting the effects of other antidepressants. As with all medications, how it, works for you may be different than how it works for others. One benefit is that it is weight neutral. With your diabetes, zyprexa is not an option. It is also not sedating like seroquil. Give it a try. ...Read more

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Is it possible to be only on antipsychotics for some time and then discontinue? Will schizophrenia be healed? All gone with zyprexa and then Abilify (aripiprazole)

Is it possible to be only on antipsychotics for some time and then discontinue? Will schizophrenia be healed? All gone with zyprexa and then Abilify (aripiprazole)

We wish so, but no: Unfortunately, current treatment of schizophrenia is able to manage symptoms only -- and not cure the condition. Medications can keep symptoms at bay, and working closely with your psychiatrist will allow you to have the healthiest life you can overall. If you stop your antipsychotic medications, chances are very good that symptoms of schizophrenia will return. ...Read more

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Does Abilify or geodon (ziprasidone) or zyprexa have less side effects? Which one has less prolactin elevation

Does Abilify or geodon (ziprasidone) or zyprexa have less side effects? Which one has less prolactin elevation

They all do it: All of these drugs will elevate prolactin. But this prolactin elevation is usually mild and of little consequence. It is far more important to get on medications that effectively treat your psychiatric condition. ...Read more

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Is abilify associated with as much weight gain as zyprexa and Seroquel. And if so is it dose related?

Is abilify associated with as much weight gain as zyprexa and Seroquel. And if so is it dose related?

Wt gain: Each of these atypical antipsychotics are associated with cholesterol problems and weight gain. According to studies of populations of individuals, Zyprexa is associated with the most weight gain of the three, Seroquel is in the middle and Abilify is the least. Each person is different.

I've certainly seen significant (20 lbs+) weight gain from each of these agents. ...Read more

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Out of zyprexa and Abilify (aripiprazole) which one would lead to a greater increase in lipids? How about insulin resistance?

Out of zyprexa and Abilify (aripiprazole) which one would lead to a greater increase in lipids? How about insulin resistance?

Lipids and insulin: Zyprexa might lead to more change in lipids and Insulin resistance than abilify, (aripiprazole) because Abilify (aripiprazole) is supposedly more weight neutral. However, Abilify (aripiprazole) can still create these effects, and increase likelihood of metabolic syndrome. ...Read more

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Zyprexa caused weight gain. Now that I am stopped and switched to Abilify (aripiprazole) my belly is out. Is this from Abilify (aripiprazole) or what?

Zyprexa caused weight gain. Now that I am stopped and switched to Abilify (aripiprazole) my belly is out. Is this from Abilify (aripiprazole) or what?

See below: Abilify (aripiprazole) is far less likely to cause carbohydrate cravings than zyprexa. That said, cravings or trouble controlling food intake occur regardless of medications in many people. ...Read more

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I take 30-40mg of Abilify (aripiprazole) for Bipolar I. I'm having moderate to severe mania. Could I add 1.25 to 2.5mg of zyprexa short-term to stop the mania?

I take 30-40mg of Abilify (aripiprazole) for Bipolar I. I'm having moderate to severe mania. Could I add 1.25 to 2.5mg of zyprexa short-term to stop the mania?

See MD: Moderate to Severe mania is not something you should be trying to medicate yourself. Please see your prescribing MD as soon as you can for further guidance. It appears you are on some medications that should be evaluated given your symptoms.

You can also seek emergency help if you so feel necessary based on severity of your symptoms. ...Read more

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Dr added zyprexa to my antidepressants many months back. Still depressed. Would replaceing zyprexa w Abilify (aripiprazole) b better, and how are they different?

Dr added zyprexa to my antidepressants many months back. Still depressed. Would replaceing zyprexa w Abilify (aripiprazole) b better, and how are they different?

Different: They are fairly different. abilify (aripiprazole) is indicated for augmenting antidepressants; its less sedation; has less weight gain; and less impact on lipids & sugar. abilify (aripiprazole) modulates receptor activity instead of completely blocking it - therefore it tends to have fewer side effects. That said, zyprexa can be extremely helpful despite its side effect burden. ...Read more

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Will Abilify cause weight loss or weight gain? I experienced weight loss on geodon (ziprasidone) but not prescribed it anymore. Experienced weight gain on zyprexa

Abilify (aripiprazole): Among antipsychotics, Abilify (aripiprazole) is considered more weight neutral. On any of these medications, it's important to be mindful of healthy nutrition and consistent exercise. ...Read more

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By taking just 1 tablet of Zyprexa can my hormons be disturbed? Currently I am on Abilify (aripiprazole). Also on glocuphage for pcos. Why 5days late for periods?

By taking just 1 tablet of Zyprexa can my hormons be disturbed? Currently I am on Abilify (aripiprazole). Also on glocuphage for pcos. Why 5days late for periods?

Maybe: abilify (aripiprazole) and zyprexa are pretty potent psych drugs that can cause multiple symptoms and affect the liver and central nervous system.
PCOS also can affect your hormone levels.
it would not be surpising to see hormonal changes with this set of facts. ...Read more

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38y f schizophernic, ptsd, severe anxiety, I tried zyprexa, abilify, (aripiprazole) latuda&always gain massive weight@#392. Other meds=bad side effects too. Suggestions?

38y f schizophernic, ptsd, severe anxiety, I tried zyprexa, abilify, (aripiprazole) latuda&always gain massive weight@#392. Other meds=bad side effects too. Suggestions?

Multiple approaches: At the weight your describe you might need to approach the weight from multiple approaches - diet, exercise and discussing with you regular doctor whether you are a candidate for gastric bypass surgery, and if not, how you can become a suitable candidate for same. Your psychiatrist will need to be part of this discussion with you your doctor as he/she will need to help you avoid certain meds. ...Read more

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Do any of these drug combinations work? Prozac abilify, (aripiprazole) Prozac zyprexa, wellbutrin zyprexa, for schizophrenia.

Do any of these drug combinations work? Prozac abilify, (aripiprazole) Prozac zyprexa, wellbutrin zyprexa, for schizophrenia.

Yes: Antidepressants, mood stabilizers, and antipsychotic medications are often combined to treat schizophrenia. The decision is best made by the treating psychiatrist and the patient. ...Read more

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Friend takes 2000 depakote/20 zyprexa/4 mg klonopin/15 abilify (aripiprazole).For bipolar schitzophrena. Does this seem like a heavy regime. Always craves chocolates?

Friend takes 2000 depakote/20 zyprexa/4 mg klonopin/15 abilify (aripiprazole).For bipolar schitzophrena. Does this seem like a heavy regime. Always craves chocolates?

Zyprexa, Abilify (aripiprazole): And Depakote and all cause stimulation. It's difficult to say what is overkill when it comes to a polypharmacy situation with someone with bipolar schizoaffective disorder. The use of two antipsychotics is indeed sometimes necessary. However, great attention should also be paid to the weight issues. If the weight gain is on going then perhaps a different medication will need to be tried, but all of that will need to be left up to of the prescribing psychiatrist. Best wishes and I hope that you are not freezing as badly in madison as we are here in racine. ...Read more

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Does abilify, (aripiprazole) zyprexa, or trazodone cause red eyes? I've had red eyes for months and only taking trazodone now. Discontinued others and many others

Does abilify, (aripiprazole) zyprexa, or trazodone cause red eyes? I've had red eyes for months and only taking trazodone now. Discontinued others and many others

Psych meds & eyes: In theory, Bc all if the meds you've listed are anticholinergic to some degree, they could contribute to dry eyes, which could lead to rubbing, irritation, & red eyes. However, you describe the problem has been ongoing for months now! Have this checked by your doc &/or an ophthalmologist, who can assess for other medical causes and treat if necessary. Be good to your eyes -- they're quite useful! ...Read more

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Zyprexa, seroquel, risperdal, Abilify all can have porential risk of raising blood sugar...Does latuda (lurasidone) carry this risk also. Not to familiar with it?

Zyprexa, seroquel, risperdal, Abilify all can have porential risk of raising blood sugar...Does latuda (lurasidone) carry this risk also. Not to familiar with it?

Latuda (lurasidone) Diabetes: Between five and 12% of patients studied on Latuda (lurasidone) developed blood sugar levels greater than 126 during the study period. A lot of this has to do with the various doses and it was not a linear increase with the doses studied. ...Read more

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I have been on seroquel geodon (ziprasidone) Abilify I could diet on geodon (ziprasidone) lose weight now on zyprexa are there non weight gain psychotics? Abilify didn't sedate me

I have been on seroquel geodon (ziprasidone) Abilify I could diet on geodon (ziprasidone) lose weight now on zyprexa are there non weight gain psychotics? Abilify didn't sedate me

A matter of degree: The newest agents in the antipsychotic class such as Vraylar, Saphris and Latuda are known for being closer to weight-neutral, though some amount of weight gain (a few pounds) is still observed in clinical trials even with these drugs. ...Read more

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I have dry mouth. Can medicine cause them when I stop taking them? Stopped geodon, (ziprasidone) zyprexa, abilify, seroquel? Still have dry mouth and tongue.

I have dry mouth. Can medicine cause them when I stop taking them? Stopped geodon, (ziprasidone) zyprexa, abilify, seroquel? Still have dry mouth and tongue.

Stay adequately: Hydrated and make sure your prescriber is aware. Please get tested for sjögren's syndrome which can cause chronic dry mouth. Dry mouth should not continue after the meds are stopped. Talk to your family doctor about treatments of dry mouth that are available, including Bethanechol and xyzal (levocetirizine). Best wishes. ...Read more

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Why can't I seem to breathe through my nose? Using my mouth too much and getting sore throats dry mouths. Was taking zyprexa and Abilify (aripiprazole) and others etc

Why can't I seem to breathe through my nose? Using my mouth too much and getting sore throats dry mouths. Was taking zyprexa and Abilify (aripiprazole) and others etc

Please get your: Nasal passages checked. Deviated septum can do this, and some meds side-effects are drying. Peace and good health. ...Read more

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Tried geodon, (ziprasidone) risperdal, abilify, haldol, seroquel, zyprexa and dislike all them. For paranoid schizophrenia. Don't like insomnia, akathisisa, weightga

Tried geodon, (ziprasidone) risperdal, abilify, haldol, seroquel, zyprexa and dislike all them. For paranoid schizophrenia. Don't like insomnia, akathisisa, weightga

Talk w/psychiatrist: You have not asked a question here, but have expressed your displeasure with some of the available antipsychotic medications for your illness. Please discuss this with your own psychiatrist, as there are still other options available. Paranoid schizophrenia is a serious illness and does need treatment. Best wishes. ...Read more

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Can I take Abilify (aripiprazole) and olanzapine together?

Can I take Abilify (aripiprazole) and olanzapine together?

Yes but: They are two meds of the same class but can feel very different. Abilify (aripiprazole) tends to cause insomnia while Olanzapine is very sedating. Raising the dose of Abilify (aripiprazole) may cause sedation at or above 20mg, reducing the need for olanzapine. Olanzapine has a lot of wt gain and problems with blood sugars and is usually reserved for patients who haven't responded to other agents. ...Read more

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Are Abilify (aripiprazole) and zeprexa in the same family of drugs?

Are Abilify (aripiprazole) and zeprexa in the same family of drugs?

Yes and no: Both are atypical antipsychotics.Zyprexa is a thienobenzodiazepine. Abilify (aripiprazole) is a part of a drug class simply called " other antipsychotics" but includes piperazine in its complex structure. ...Read more

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Which drug works best in most cases for bi polar? Olanzapine, isperidone, quetiapine, aripiprazole, lamectal?, and a new drug that begins with an "f"?

Which drug works best in most cases for bi polar? Olanzapine, isperidone, quetiapine, aripiprazole, lamectal?, and a new drug that begins with an "f"?

Bipolar: I think your "f" drug may be fanapt, or iloperidone. And maybe you meant "risperidone." all of these antipsychotics may be used in acute mania or psychotic depression, along with other mood stabilizers. But only asenapine, olanzapine, quetiapine, risperidone, ; ziprasidone have fda indication as monotherapy in acute mania or depression. Maintenance: Risperidone consta (and Olanzapine in ca). ...Read more

Dr. Alan Ali
251 Doctors shared insights

Zyprexa (Definition)

Zyprexa is a serotonin-dopamine receptor blocker which is a kind of atypical anti-psychotic drug (drug ...Read more