Doctor insights on:
Switching From Humira To Enbrel For Rheumatoid Arthritis Naturopathy
Second line.: While Enbrel (etanercept) can be used alone, it works better in tandem with methotrexate. It is given by subcutaneous injection once per week, the dose being dependent on body size. It is also indicated for psoriatic arthritis and spondylitis. Most insurers want the patient to have been on lesser drugs. These would include incomplete response to mtx, sfz, and ho-q. It binds to tnf-alpha, which caues inflamm. ...Read more
A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
Very effective.: But frequently unecessary in most of my RA patients. Combinations inclduing mtx with sulfasalazine, hydroxychlorquine, perhaps doxycycline, or Leflunomide should be tried before starting enbrel, (etanercept) unless you have overwhelming inflammatory disease. Noenthless, Enbrel (etanercept) with mtx is better than either alone! ...Read more
Many patients: Rheumatoid arthritis can often be controlled with some of the newer medications including enbrel (etanercept). Many patients are saved from irreversible crippling of the joints. The key is to get early diagnosis and effective treatment to prevent worsening. Enbrel (etanercept) is a biologic response modifier meaning that the drug is made by a biological system. The drug can be very effective. Untreated RA has huge risks. ...Read more
Would any rheumatologist ever suggest enbrel (etanercept) to a patient who doesn't have rheumatoid arthritis, anspon, juvenile or psoriatic arthritis? Serious drug
Yes: Enbrel (etanercept) does have value in other disorders so I have recommended its use in diseases not on your list. ...Read more
My mom has been using Enbrel and have diagnosed with Parkinson. Is that kind of Rheumatoid Arthritis biologic treatment dangerous for Parkinson or not?
Enbrel: And its use in the presence of a neurologic disease as Parkinson or in an elderly patient? A question of risk/benefit ratio, some biologicals need to be used with caution above age 65, enbrel is one of them, also in patients with demyelinating disease, Parkinson isn't, so this delicate and complex question need to be answered in a clinical context, the best to do so is the treating doctor/team, ...Read more
Dx of rheumatoid arthritis. Taking Enbrel and occasionally prednisone burst pack. Chronic debilitating pain, not EVEN touched by OTC meds, or ensaids. Please help!!!!!!
You need to have a frank discussion with your Rheumatologist1 the treatment of RA has advanced greatly over the past decade. Biological therapy and combination of various medications usually result in control of pain and joint damage! SPEAK OUT!!
Hope this helps and BE WELL!
Dr Z ...Read more
Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?
Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more
Yes: Tnf agents such as Humira (adalimumab) are extremely effective in controlling RA and preventing joint damage and deformities. ...Read more
Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it binds to tnf-a rendering ineffecftive. It is completely human in origin. A good choice for those who do prefer home sc injection, every two weeks. It is my favorite tnf-a class drug. ...Read more
Very effective!: Good drug for severe RA!Get a more detailed answer ›
MTX vs Humira (adalimumab): These drugs fight RA in completely different fashions. Mtx is the consensus first round choice of drugs to treat ra, both by the acr and eular (european version). Most, if not all, insurances require treatment failure with mtx before you start humira, (adalimumab) a much more expensive drug. In most cases, even if Humira (adalimumab) is started, patients will remain on mtx. ...Read more
It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more
Yes, but.....: Humira (adalimumab) is quite effective. It is also quite expensive. It should not be considered a first-line therapy, as drug companies want us to believe. Other first line dmards like plaquenyl, methotrexate, leflunomide, and sulfasalazine work quite well. I occasionally will give Humira (adalimumab) injections for several visits until other drugs kick in. ...Read more
Could Humira (adalimumab) cause drug-induced lupus on the head? Some small lesions on the head. (Rheumatoid arthritis)
I have rheumatoid arthritis and take methotrexate and humira (adalimumab) injections. I want to get look better by getting filler for my face. Please let me know which ones are not in conflict with my medications. Thanks?
Filler options: You need to avoid sculptra with RA as you may be at increased risk for nodule and granuloma formation. Ha fillers like juvederm or Restylane (dermal fillers) should be safe but last only a year or so. Fat transfer is a good long term option but has more down time. Consult with a local experienced facial plastic surgeon. ...Read more
Is there a drug that's less expensive and can be used as a alternative to humira (adalimumab) for rheumatoid arthritis?
YES: There are multiple drugs for arthritis cheaper than humira. Pills like methotrexate, sulfasalaxine, Plaquenil (hydroxychloroquine) and Leflunomide can be used alone or in combination. There is also an injectable form of Methotrexate that can sometimes be more effective. Prednisone can also be taken. Non-steroidal anti-inflammatories can be used. Depending on your insurance, another biologic may be cheaper than humira. ...Read more
I am taking humira (adalimumab) for rheumatoid arthritis. Now I have rashes on both of my arms. What could have caused that?
30yr old taking methotrexate, prednisone, and humira (adalimumab) for rheumatoid arthritis. AF on 4/14. Aweek later had spottin. BFN 4/23. Today Day11 of spotting
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