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Doctor insights on: Swelling Knee Joints From Prednisone

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Dr. Thomas Namey
2,503 doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


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I've got stills im 23, my joints r swollen I've been on prednisone high doses for months, I've had cort. Shots in knees, n ntfs don't work, what will help?

I've got stills im 23, my joints r swollen I've been on prednisone high doses for months, I've had cort. Shots in knees, n ntfs don't work, what will help?

Other Rx: Even though tnfs did not help, there are other biologic agents which have shown good results. One drug is Kineret (anakinra) which works on il-1 ( interleukin-1) instead of tumor necrosis factor (tnf). Be sure to let your rheumatologist know that you are still in pain and that you cannot taper off the steroids. ...Read more

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Severe joint pain in hips feet toes hands fingers knees elbows morning stiffness daily 20 mg prednisone no help MRI no inflam ANA 1:320 help?

Severe joint pain in hips feet toes hands fingers knees elbows morning stiffness daily 20 mg prednisone no help MRI no inflam ANA 1:320 help?

Try DMSO: DMSO (dimethylsulfoxide)--aka horse liniment--is available at a health food store or feed/veterinary supply. For systemic inflammatory conditions as you apparently have, I suggest one tsp per day orally. It tastes terrible. Mix with a small amount of water, and chase it with something else to kill the taste. Major adverse effect is that you will "off-gas" the DMSO in your breath and sweat. ...Read more

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What causes swelling on the knee joint?

What causes swelling on the knee joint?

Injury or arthritis: Injury or some type of arthritis, as well as some types of inflammatory diseases can cause your symptoms. You should see your doctor for an exam and diagnosis. ...Read more

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How effective is mobic (meloxicam) in reducing swelling of the knee joint that causes pain in ostoarthritis?

How effective is mobic (meloxicam) in reducing swelling of the knee joint that causes pain in ostoarthritis?

Not much: While we often give "antiinflammatories" like candy to control pain and inflammation, the medications have only a very small affect on swelling. The majority of the benefits of the antiinflammatories are the pain-relieving aspects. They also have almost no affect on swelling inside the knee from osteoarthritis. Most of the fluid occurs from mechanical wear or bleeding within the joint. ...Read more

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I have still's d. I've been on kineret (anakinra) for 5days, but pain n swelling is not going away, am I causing damage to my joints by walking w.Swollen knees?

I have still's d. I've been on kineret (anakinra) for 5days, but pain n swelling is not going away, am I causing damage to my joints by walking w.Swollen knees?

Limit weight bearing: You didn't indicate your age or how long you have had this problem. In early childhood it is important to rest the affected joints as well as splinting with intermittent range of motion to prevent contractions (stiffness) and preserve motion. Sequelae in the adult years are treated with anti-inflammatory medications. An adult needs to limit weight bearing until the joint swelling improves. ...Read more

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My ankle, knee, and elbow is swelling at the joints. The pain is excruciating. What could this be?

My ankle, knee, and elbow is swelling at the joints. The pain is excruciating. What could this be?

arthritis: You have arthritis of multiple joints. Please see a doctor to diagnose and treat your condition. ...Read more

Dr. David Schleimer
1,498 doctors shared insights

Swelling (Definition)

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more


Dr. Stratos Christianakis
1,189 doctors shared insights

Joints (Definition)

Joints are parts of the body, formed by the cartilage-covered ends of bones plus the strong, flexible ligaments that attach the bones to one another. Movements at the joints in the body allow the different parts of the body to move in ...Read more