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Doctor insights on: Sweat Chloride Test

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Dr. Katharine Cox
25 doctors shared insights

Sweat Chloride Test (Overview)

The sweat chloride test is the first line test for diagnosing cystic fibrosis. The results may be abnormal (diagnosis of CF), normal (CF very unlikely) or intermediate (possible CF, needing further testing). In young babies the intermediate range is very broad, because the sweat glands are still developing.


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How reliable is a sweat chloride test in ruling out cf?

How reliable is a sweat chloride test in ruling out cf?

Cystic fibrosis: The sweat test is usually done when the infant is a month old, to ensure the sample is large enough to be analyzed. The sweat test can determine if the infant carries the cystic fibrosis gene or has the condition. Testing should be done at a center specializing in cystic fibrosis. ...Read more

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Dr. Katharine Cox
25 doctors shared insights

Sweat Chloride Test (Overview)

The sweat chloride test is the first line test for diagnosing cystic fibrosis. The results may be abnormal (diagnosis of CF), normal (CF very unlikely) or intermediate (possible CF, needing further testing). In young babies the intermediate range is very broad, because the sweat glands are still developing.


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How reliable is a sweat chloride test in ruling out cf?

Cystic fibrosis: The sweat test is usually done when the infant is a month old, to ensure the sample is large enough to be analyzed. The sweat test can determine if the infant carries the cystic fibrosis gene or has the condition. Testing should be done at a center specializing in cystic fibrosis. ...Read more

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Sweat chloride testing for cystic fibrosis=standard tests?

Yes, Gold Standard: The gold standard for a diagnosis of CF is 2 back-to-back sweat chloride tests. However, the ability to run genetic tests and detect the disease in this fashion is becoming more common. In fact, it is now standard procedure in all 50 states for newborn babies to be screened, via blood from a heel prick, for cystic fibrosis. ...Read more

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How reliable is a negative sweat chloride at ruling out CF in someone?

How reliable is a negative sweat chloride at ruling out CF in someone?

See below: The sweat chloride test is the gold standard for diagnosing cf. If an adequate amount of sweat was obtained, and the test was negative, then CF is unlikely. ...Read more

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I have neprhocalcinosis, today I had a renal function test done and my BUN was 7 & chloride 112, other levels normal. What could this mean?

I have neprhocalcinosis, today I had a renal function test done and my BUN was 7 & chloride 112, other levels normal. What could this mean?

Labs: Your BUN is lower and maybe a reflection of your protein intake but doesn't mean disease. BUN levels are governed by many reasons including kidney function protein intake liver issues. Assuming you have no issue low BUN is more diet. Your chloride is high normal and should hair be repeated. These labs have to be looked in totality and don't mean disease. Best of luck ...Read more

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I am suffering with hypocalcium disease let me know how it will come and why amonia chloride test will do for humans because they did for me ?

Ammonia chloride: If the blood work did show low serum calcium there are many other tests that need to be done. An ammonia chloride test is a minor concern until all the appropriate labs are completed. How low is your calcium? ...Read more

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Dr. Leonard Stein
185 doctors shared insights

Chloride (Definition)

Chloride is a negatively charged ion of chlorine found in cells and serum. Chloride is the main ion which balances out the positively charged ions ...Read more