Doctor insights on:
Been on surmontil (trimipramine) 50 mg. For 12 yrs. Now generic doesn't seem as effective. Is generic the same formulation?
Yes and no: Generics must contain the same active ingredient as the branded product, but other ingredients (fillers) or delivery system (capsule vs pill vs gelcap vs specialized release system) may be different. Generics from other countries may not be tested as thoroughly to make certain dose of active ingredient is consistent. Discuss concerns with fp/doc &/or pharmacist. ...Read more
Unknown: We can neither endorse nor prohibit it during pregnancy. Some similar medicines have been studied, but the results are inconclusive. There may be an increase in risk; on the other hand, if it is helpful to the mother, there may be an increase in risk without it. Consider dosage, trimester, risks and benefits, and involvement of the father and obstetrician, in deciding. ...Read more
Caution advised: The combination together has an increased risk of low blood pressure episodes, seizures, central nervous system depression, psychomotor impairment, and risk of serotonin syndrome. You should discuss this with your physician and as long as you agree to accept the risk, there is no absolute contraindication to taking them together. ...Read more
Supportive Treatment: Whenever someone intentionally or unintentionally overdoses with any medication, it is an emergency. The individual should be brought to the emergency room immediately. Life support measures are given as necessary. Side effects are treated and managed until they resolve. Then a psychiatric eval once medical stability achieved. If suicidal involuntary hospitalization. If accidental determine cause. ...Read more
I don't feel the same after taking generic surmontil (trimipramine). I feel more depressed and anxious. Is this normal? Been on generic about a week.
Brand before?: Answer depends on whether you have been taking brand surmontil (trimipramine) previously. But not a pharm answer! the placebo effect is powerful, both positive and negative, it's possible that your worry about generic being less effective is causing you serious anxiety. It's too soon for a pharm effect, if there were one (unlikely). Give it some time--and do some reading on placebo, it will really be helpful. ...Read more
There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more
So call your doc: This is the HT public information site.We are thousands of volunteer docs based primarily in the US who answer medical questions.We do not offer treatments. State medical boards require a physician/patient relationship,a retrievable record,recent exam with vital signs for prescribing.Failure to do so can lead to loss or restriction of license. It may seem minor to you but it is not. ...Read moreSee 1 more doctor answer
Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more
ASPRIN: Actually no one has decided on 'safest'. Asprin has been around since before you were born and unless you take too much (yes, too much of anything isnt good) most people are okay with it. If the pain it too severe for asprin you need to know what causes it. Good diagnosis is called for. See the dr. ...Read more
Applies to skin: Topical just refers to how a medication is applied. In this case to the skin and is meant to treat local skin problems. Some meds are applied to the skin but are meant to be absorbed into the body in which case we use the term "transdermal" since it is meant to pass through the skin to affect the whole body. ...Read more