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Doctor insights on: Supratherapeutic Anticoagulation

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How effective is warfarin (Coumadin) for managing atrial fibrillation?

Warfarin: Warfarin doesn't manage atrial fibrillation. It is an anticoagulant we give to afib patients to decrease the possibility of their having a clot form and cause an embolus to the brain or other part of the body. ...Read more

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Can thrombolysis be used for deep vein thrombosis?

Can thrombolysis be used for deep vein thrombosis?

Yes: Currently, most protocols for the treatment of DVT do not include thrombolysis unless the clot is very extensive. ...Read more

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How effective is pradaxa dabigatran as an alternative to coumadin (warfarin)?

How effective is pradaxa dabigatran as an alternative to coumadin (warfarin)?

Pretty good, but...: They are essentially equivalent in thinning the blood to replace coumadin (warfarin), (warfarin) but they require twice daily dosing. Yes, you don't have to get your blood tested like you do with coumadin (warfarin), (warfarin) but if you have a bad bleed, there is no antidote for either you mentioned, like there is for coumadin (warfarin). So one must weigh the risks vs. The benefits, as we do everyday in medicine. ...Read more

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What is warfarin, the anticoagulation therapy drug?

Blood thinner: Bloid thinner that inhibits clotting by interfering with vitamin k. ...Read more

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Why warfarin used in long term treatment of deep venous thrombosis? Why not heparin?

Why warfarin used in long term treatment of deep venous thrombosis? Why not heparin?

Oral administration.: Warfarin is available in an oral dose and is given on a daily basis. Its effects lasts 24 hours and takes about 72 hours to clear from your system. Heparin is given either intravenously or subcutaneously and requires dosing every 4 to 8 hours or continuously depending on the method of administration. Long term anticoagulation is easier and better tolerated with an oral medication. ...Read more

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Which is least invasive of rf procedures for the patient, re: venefit targeted endovenous therapy vs. Vnus closure system for varicose veins?

Which is least invasive of rf procedures for the patient, re: venefit targeted endovenous therapy vs. Vnus closure system for varicose veins?

Veins: All are equally minimally invasive All have similar outcomes All are tolerated well It's more related to the procedure your treating physician does ...Read more

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Medical Records state, GASTROINTESTINAL PROPHYLAXIS W/PROTON PUMP INHIBITOR & DEEP VEIN THROMBOSIS PROPHYLAXIS W/SEQUENTIAL COMPRESSION DEVICE. What does that mean?

Medical Records state, GASTROINTESTINAL PROPHYLAXIS W/PROTON PUMP INHIBITOR & DEEP VEIN THROMBOSIS PROPHYLAXIS W/SEQUENTIAL COMPRESSION DEVICE. What does that mean?

Precaution care: It sounds like these are precautions taken to prevent surgical or hospitalization (bedrest) complications due to inactivity and not eating. Stomach acid is reduced with proton pump inhibitor meds and deep vein thrombosis caused by venous stasis prevented with a device that wraps around the calves and squeezes intermittently. ...Read more

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Advised recent data suggest medication management may be as successful as Carotid Endarterectomy surgery stroke prevention with 50%Occluded,But where?

Advised recent data suggest medication management may be as successful as Carotid Endarterectomy surgery stroke prevention with 50%Occluded,But where?

Cochrane Reviews: As of 2011 Carotid Endarterectomy was of marginal benefit in those with Stenosis 50%-69% and of no greater benefit in Stenosis 30-49% ... see http://www.ncbi.nlm.nih.gov/pubmed/21491381?dopt=Abstract Putting Endarterectomy into the search engine at http://onlinelibrary.wiley.com/ gives recent data. Give most weight to a Systematic Review.. Do note most of the Stenoses under study are are >70%. ...Read more

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Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?

Are  any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?

Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more

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How effective is warfarin (Coumadin) for treating stroke?

How effective is warfarin (Coumadin) for treating stroke?

Depends on the type: Coumadin (warfarin) is effective in preventing stroke from blood clots that originate in the heart. These can be from atrial fibrillation, clot on a heart valve, or from a damaged left ventricle.T he new anticoagulants (Eliquis, Pradaxa) are also effective in treating atrial fibrillation that is not assoicated with a valve problem.Coumadin (warfarin) is not recommended for strokes from carotid artery disease . ...Read more

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Are medical alert bracelets required for Coumadin (warfarin) patients?

Are medical alert bracelets required for Coumadin (warfarin) patients?

Not required, but...: A good idea. If you are unconscious and found bleeding, there are antidotes to coumadin, (warfarin) fresh frozen plasma and vitamin k to reverse it. So a good idea to wear a bracelet, especially if you are on it long term, like with a prosthetic heart valve or chronic atrial fibrillation. ...Read more

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Is xarelta as effective in treating blood clots as warfarin?

Is xarelta as effective in treating blood clots as warfarin?

Xarelto: Yes. Xarelto (rivaroxaban) is equally effective as coumadin( warfarin). Initially it was given only for irregular heart beat atrial fibrillation. Now the use is expanded to leg clot DVT and lung clot pe. The advantage of xarelto over Coumadin is that there is no periodic blood checkup for pt/ inr just like coumadin. It can be expensive & inconvenient. Can't monitor level & no antidote. ...Read more

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Is operation the only option for deep vein thrombosis with pulmonory embolism?

Is operation the only option for deep vein thrombosis with pulmonory embolism?

Depends: Surgical treatment is usually reserved for massive pulmonary embolism (pe) or in chronic pe cases. In most instances DVT and pe are treated with clot dissolving drugs (thrombolysis) and blood thinners (anticoagulation). Sometimes DVT is treated "invasively" by an interventional radiologist to help direct the therapy to the clot directly. ...Read more

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Why thrombolytic therapy is contraindicated in aortic dissection?

Why thrombolytic therapy is contraindicated in aortic dissection?

Bleeding risk: Because doctors tries to balance the possible benefits to the risk of harm. And here with aortic dissection, there is an increased risk of bleeding that exceed the desired benefit, which makes thrombolytic contraindicated in those patients. ...Read more

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Will clopidogrel (7mg/day) compliment warfarin therapy for patients with CHF with a-fib? Is it really required? +dabigatran?

Will clopidogrel (7mg/day) compliment warfarin therapy for patients with CHF with a-fib? Is it really required? +dabigatran?

Coumadin/dabigatran: Coumadin (warfarin) or dabigatran. You can not be on both because of increased risk of bleeding. With either Coumadin (warfarin) and dabigatran you do not need to be on plavix. ...Read more

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What does term anticoagulation mean?

What does term anticoagulation mean?

Prevents blood clots: Medications that prevent, or slow down the rate of forming blood clots. ...Read more

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What is the role of anticoagulation in stroke?

Questinable: I presume you are asking about heparin/coumadin. They are used in condition like dissection of artery to brain-still not a evidence based, atrial fibrillation or source of emboli from heart, some hyper coagulate states.Use of Heparin in other type of stroke is not advised. ...Read more

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Can you tell me in nephrotic syndrome, why are anticoagulation molecules preferentially lost?

Can you tell me in nephrotic syndrome, why are anticoagulation molecules preferentially lost?

Proteins: They are not preferentially lost. All serum proteins are lost. Anticoagulation molecules are proteins. They are lost. ...Read more

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What is warfarin, the anticoagulation therapy drug?

Blood thinner: Bloid thinner that inhibits clotting by interfering with vitamin k. ...Read more

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Why are some clots difficult for the body to break down? Blood thinners are used to thin blood, which aids in the natural anticoagulation, correct?

Why are some clots difficult for the body to break down? Blood thinners are used to thin blood, which aids in the natural anticoagulation, correct?

An example may help: Heart-attacks are frequently caused by the rupture of a plaque in an artery in the heart. A clot forms over the injury but this also occludes the vessel that supplies part of the heart. The clotting system is responding properly to vessel damage and doesn't know that the clot is iinjurying the heart. Blood thinners can break up clots like this allowing blood to flow back to the heart. ...Read more

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Does etoh have any anticoagulation properties? I had asked this question earlier, which was answered very promptly, but did not directly answer the question. I am taking warfarin for a 1.5 CM pe in the right upper lobe. For a week, i stopped my warafrin

Does etoh have any anticoagulation properties? I had asked this question earlier, which was answered very promptly, but did not directly answer the question.  I am taking warfarin for a 1.5 CM pe in the right upper lobe.  For a week, i stopped my warafrin

Bad idea: Unless directed by your physician stopping your warfarin therapy for a pe is a bad idea. While alcohol (ethanol, or etoh) has anitiplatelet properties, it is not an approved treatment for pulmonary embolism or deep venous thrombosis (dvt). Substituting alcohol for warfarin is a really, really bad idea. I suggest you have your inr checked and consult your physician asap. ...Read more

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Is anticoagulation effective in pregnancy? Wil it defenitely stop blood clotting?

Is anticoagulation effective in pregnancy? Wil it defenitely stop blood clotting?

Effective: Anticoagulation is effective however options are limited in pregnancy. Anticoagulation reduces risk of abnormal clotting in most, however does not eliminate the risk. ...Read more

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Can anticoagulation keep DVT away in pregnancy?

Helps: There is no 100% guarantee that anticoagulation will prevent DVT during pregnancy. There is no reason to be on anticoagulation unless you have had a prior dvt, are a high risk pregnancy or are hypercoagulable. Certainly the imput of your ob/gyn and either a vascular surgeon or vein specialist would be important.There are many routine things to do during pregnancy to prevent DVT such as supp hose. ...Read more

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Do i need to stop anticoagulation for DVT in order to get a tattoo?

Do i need to stop anticoagulation for DVT in order to get a tattoo?

Not recommended: Better to ask tattoo artist if they will do it while your on coumadin (warfarin). You could also ask whomever prescribed it, but ask your self: "would I rather bleed from having a tattoo or have another DVT (which could lead to a pulmonary thromboembolism and sudden death) from stopping my anticoagulant?" If you can answer that question you don't need any more input. Or just don't get a tattoo. ...Read more

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Why do doctors recommend against anticoagulation in cancer patients with platelets < 50,000?

Why do doctors recommend against anticoagulation in cancer patients with platelets < 50,000?

Increased bleeding r: Both conditions increase the risk of bleeding. If you bleed due to anticoagulation, low platelet count that you already have will markedly increase the risk of hemorrhage and death as a result. ...Read more

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Can u die in pregnancy if on clexane (;anticoagulation) if had DVT in past?

Can u die in pregnancy if on clexane (;anticoagulation) if had DVT in past?

Unlikely: If you had a dvt, obviously that's why your doctor recommended you be on enoxaparin. While pregnancy is a state of increased possible thrombosis, the medication does help to prevent them. Follow your doctors instructions, exercise with light walking as much as you can, you should be fine. ...Read more

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Can DVT occur whilst on anticoagulation treatment in pregnancy, ?

Can DVT occur whilst on anticoagulation treatment in pregnancy, ?

Yes: Dvt can occur while on anticoagulation and also while pregnant and on anticoagulation. If either of these occurs, it usually means that the anticoagulation has been at unacceptable levels. You need close monitoring and probably, should be followed by a hematologist. ...Read more

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What reason behind infection(suppurative inflammation)or clots in the colon 1week after colon partial resection surgery(while taking anticoagulation)?

Surgical complicatio: This sounds like a complication of the surgery and you should be seen by the surgeon and managed appropriately. Good luck. ...Read more

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Does anticoagulation in pregnancy stop blood clotting? Does treatment stop DVT completely

Does anticoagulation in pregnancy stop blood clotting? Does treatment stop DVT completely

No.: Dvt can occur while on anticoagulation and also while pregnant and on anticoagulation. If either of these occurs, it usually means that the anticoagulation has been at unacceptable levels. You need close monitoring and probably, should be followed by a hematologist. ...Read more

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91 yrs.My GP not interested in my enlarged scrotum also not on Anticoagulation with diagnosed Heart Failure.Is there alternative to taking digoxin ?

91 yrs.My GP not interested in my enlarged scrotum  also not on Anticoagulation with diagnosed Heart Failure.Is there alternative to taking digoxin ?

Many physicians: believe that at 91 a "minimalist" approach is indicated. IFor example the scrotal swelling is most likely a hernia but if not symptomatic surgery probably not wise in the nineties. Likewise unless Digoxin is causing problems , why replace it (There ARE alternatives). Finally ANTICOAGULATION is probably more risky than their BENEFITS at age 90 plus! In other words IF IT AIN'T BROKE DON'T FIX IT! Z ...Read more

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Am I dying?

Am I dying?

We all are: A 3-word question with no details... well, life is short on Earth, regardless of whether a person lives 3 days, 3000 days, or 30,000 days. It is not length of one's life that matters, but the quality of the life lived. The goal is not to live a long life, but to live a good life. Even if a person makes it all the way to age 82, that's only 30,000 days. ...Read more