Doctor insights on:
Sulfasalazine Vs Mesalamine
How does sulfasalazine measure up to other 5-asa drugs such as asacol (mesalamine) and colazal for ulcerative colitis?
I have ulcerative colitis and in the last 4 months have been on 3 different medication, apriso made me sick, lialda did nothing now I am on azulfidine and prednizone. I am not getting worst, but I am not getting any better. I put myself on a low re
Other options: There are other options, which can be considered, including biologic agents. See an experienced gastroenterologist. ...Read more
Uncertain: In general, it is recommended that medications not be used after expiration date. With that said, there is a big difference between being expired for 5 days versus 5 years. Your pharmacist should be able to provide more information. ...Read more
Azulfidine (sulfasalazine): See: http://www. Drugs. Com/sfx/sulfasalazine-side-effects. HtmlGet a more detailed answer ›
Retake: Just restart them. Typically if you miss one or two doses, nothing bad should happen in such a short period of time. However if you are ROUTINELY missing doses, you are more likely to have a flare up. If you really don't think you can take your medications without forgetting, discuss other medical options with your GI doctor ...Read more
Can you tell me if on taking these with my colitis medication which I take daily i.e. sulfasalazine?
See details: You question makes no sense. Try resubmitting it. ...Read more
Can this medicine Mesalamine normally used to treat ulcarative colitis be helpful for diabetes. Read on net soemwhere. Thanks?
Any steroids either parenteral or oral has
its risks/side effects especially in the long run. Affects a lot of organ systems. So your md who is taking care of you will brief you more of it. And remember, your condition is an auto-immune condition. What steroids and other meds being used or available is just a palliative measure - quiet down or blocks the inflammatory reaction of these condition. ...Read more
No. Relatively safe!: Sfz is one drug I use the most in patients with many diseases. Aside from an occasional "sulfa rxn", the most common side effect is stomach "queazyness". All individuals taking this drug need to be monitored with blood work at defined intervals (2-3 mo) and they should receive Folic Acid supplements. ...Read more
It depends: Sulfasalazine has a half life of 7.6 hr on avg. It's a short acting medication which is why it requires every 6-12 hour dosing. A drug is cleared from system entirely after 10 half lives so the drug should theoretically be cleared in 76 hrs or a little over 3 days. The metabolite of sulfasalazine, sulfapyridine has a half life of 10.4-14.8 h so it's cleared in 148 hrs from system ...Read more
Child eating somethi: Always call poison control to clarify the item ingested. The poison control number is usually an 800 no. And can be found in the front of your phone book, or any emergency room would have it and you could post it on your fridge or put it somewhere quickly accessible. My 10 mo old once put a handful of dishwasher soap in his mouth (not tasty!) but I called just to be sure. ...Read more
Most likely.: Yes. Unless you have a severe life-threatening adverse event. ...Read more
Yes, sometimes: Up until the 80's we only had sulasalazine for uc. The main problems were headace and some rqshes usually due to the sulfapyridine moiety. Pure Mesalamine drugs such as asacol, (mesalamine) lialda, Balsalazide and others do not contain the sulapyridine part and therefore don't have as many problems with the drug. However sulfasalazine is still cheap and useful and should not be ignored. ...Read more
Ideally you should: Be able to hold it in through the night time sleep cycle. This may take several days before you can accomplish this. The longer you hold the more effective the treatment. Let your prescribing doctopr know if after a week you are still not able to go thru the night holding the enema ...Read more
Unusual: There is no reported clinical experience with PENTASA overdosage. PENTASA is an aminosalicylate, and symptoms of salicylate toxicity may be possible, such as: tinnitus, vertigo, headache, confusion, drowsiness, sweating, hyperventilation, vomiting, and diarrhea. Ref: http://www. Rxlist. Com/pentasa-drug/overdosage-contraindications. Htm ...Read more
Asacol (mesalamine): Regular Asacol (mesalamine) is 400 mgs in strtength. Asacol (mesalamine) hd is double strength it has 800 mgs. ...Read more
Usually helps: 4000 mg is the usual dose of Pentasa. The active ingredients in Pentasa is mesalamine. It is usually well-tolerated, and very often helps with inflammatory bowel conditions in the bowel. Lists of the rare possible side effects are easily found online. The important thing is to be sure that your IBD is not worsening after starting the medication. If it is, contact your doctor. ...Read more