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Doctor insights on: Sulfamethoxazole For Acne

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What do you suggest if I was just prescribed sulfamethoxazole for my acne. When should I start to see results?

What do you suggest if I was just prescribed sulfamethoxazole for my acne. When should I start to see results?

1-2 weeks: An antibiotic must not be the sole treatment for acne, so I trust you are using benzoyl peroxide or whatever topical agent your physician recommended. If it doesn't work, there are many other things to try. ...Read more

Dr. Ed Friedlander
2,177 Doctors shared insights

Acne (Definition)

A very common skin condition that starts as a blockage of the sebaceous glands followed by inflammation. It occurs in areas where there are lots of sebaceous glands, such as the ...Read more


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What does sulfamethoxazole do for acne?

What does sulfamethoxazole do for acne?

Kills bugs: It will kill off the bacteria responsible for acne. It's not a bad antibiotic for partial management of this annoying illness; there are other medicines that can augment its effectiveness. Today all acne can be managed successfully using scientific remedies. Good luck and thanks for asking. ...Read more

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Sulfamethoxazole for cystic acne? Does it work?

Sulfamethoxazole for cystic acne? Does it work?

Not the best choice: An antibiotic must never be used as sole therapy for acne. Cystic acne may be helped by antibiotic treatment plus a topical agent such as benzoyl peroxide, but usually requires isotretinoin. You've heard the internet scare stories but most people who try this Rx -- which isn't for the faint-hearted -- are very glad. Acne's a grave personal / professional liability; ask if this is right for you. ...Read more

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How long can I be on sulfamethoxazole/trimethoprim for acne?

How long can I be on sulfamethoxazole/trimethoprim for acne?

Get 2nd opinion: This drug has been used but from my reading, a tetracycline is preferred as much safer. An antibiotic should never be the sole treatment for acne, and people are recommending now that courses of antibiotics not be longer than three months. The fact that you asked also raises concern in my mind about your relationship to your physician. I suggest a second opinion. Let's find what's right for you. ...Read more

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Does the drug sulfamethoxazole / trimethoprim treat acne I just got it for my acne?

Acne sulfa: The drug sulfamethoxazole/trimethoprim would be able to treat acne but except in unusual cases it is not a good drug to treat acne. The main reason is that there are many other safer medications to use for long term treatment, particularly members of the tetracycline family. Rarely a person can have an adverse reaction to sulfa drugs that can be very severe. I have seen 4 people die from it. ...Read more

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Accutane vs bactrim (sulfamethoxazole and trimethoprim) acne help!, what to do?

Accutane vs bactrim (sulfamethoxazole and trimethoprim) acne help!, what to do?

First try: "bactrim" isn't as good as some of the other antibiotics, especially the tetracyclines. Don't ever use an antibiotic as sole treatment for acne. Isotretinoin / Accutane is your last resort unless you have cystic acne, for which nothing else will probably work. It's not for the faint-hearted but is a remarkably effective medication. ...Read more

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I was prescribed sulfamethoxazole-tmp for acne by my derm. I took it and feel slight nausea stomach pains. Is this normal? Will I get a rash?

I was prescribed sulfamethoxazole-tmp for acne by my derm. I took it and feel slight nausea stomach pains. Is this normal? Will I get a rash?

Probably Medication: If you are experiencing nausea, it could be the medication. Additionally, one of the side effects of Bactrim (sulfamethoxazole and trimethoprim) is a rash. Consult your physician about alternative medications. ...Read more

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I took bactrim (sulfamethoxazole and trimethoprim) for acne and it cleared up my acne completely, but I got allergic to it. Is there an acne antibiotic substitute that is as effective?

I took bactrim (sulfamethoxazole and trimethoprim) for acne and it cleared up my acne completely, but I got allergic to it. Is there an acne antibiotic substitute that is as effective?

Discuss with derm: Yes there are alternative therapies such as doxycyline, coral actives - a non antibiotic, and others. Your dermatologist can discuss alternatives. ...Read more

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Is it common to take "sulfamethoxazole-tmp" pills for acne treatment (apparently its suppose to stop bacteria growth under the dark acne scar spots)?

Is it common to take "sulfamethoxazole-tmp" pills for acne treatment (apparently its suppose to stop bacteria growth under the dark acne scar spots)?

See below: Smx-tmp is one of several antibiotics used to control cases of more severe acne (tetracycline family, clindamycin, some cephalosporins, Augmentin (amoxicillin and clavulanate) are also used). If acne is mild, use topical antibiotics to avoid side effects of systemic antibiotics: e.g., smx-tmp is a notorious photosensitizer, so use sunblock while taking it. Dermatologist can optimize regimen for acne. ...Read more

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I am taking sulfamethoxazole and spironolactone for acne, but still have active jaw line acne. Could Synthroid (thyroxine) help in balancing my hormones too?

I am taking sulfamethoxazole and spironolactone for acne, but still have active jaw line acne. Could Synthroid (thyroxine) help in balancing my hormones too?

Absolutely not: Synthroid (thyroxine) should only be taken in cases of hypothyroidism and under the care of a physician, NP, or PA Taking it would increase metabolism; I doubt that this would have an effect on your acne (it's a different hormone pathway entirely) and might make it worse. See your doc or dermatologist if still having probes w/ur acne. Best of luck! ...Read more

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Is Accutane or bactrim (sulfamethoxazole and trimethoprim) better for acne, what to do?

Is Accutane or bactrim (sulfamethoxazole and trimethoprim) better for acne, what to do?

How bad is it?: Isotretinoin is the strongest and most effective medication for acne and is not for the faint-hearted. Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic and should never be used as sole therapy; a combination of topical benzoyl peroxide plus a course of systemic tetracycline often clears moderately severe acne. If you're female, the oral contraceptive pill if right for you may work; spironolactone's another rx. ...Read more

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Can sulfamethoxazole (bactrim (sulfamethoxazole and trimethoprim) ds) make your acne worse before it gets better?

Can sulfamethoxazole (bactrim (sulfamethoxazole and trimethoprim) ds) make your acne worse before it gets better?

Yes: I'd check with my physician first, though, since Bactrim (sulfamethoxazole and trimethoprim) itself is famous for producing a different kind of rash that can be dangerous. ...Read more

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I have been suffering from acne for a couple years and have been taking bactrim (sulfamethoxazole and trimethoprim) for 4 months. Acne has cleared so can I stop taking the medication?

I have been suffering from acne for a couple years and have been taking bactrim (sulfamethoxazole and trimethoprim) for 4 months. Acne has cleared so can I stop taking the medication?

Yes: You should not take an antibiotic as sole therapy for acne in any case, or any antibiotic for a long time. Your best move would be to stop this and continue whatever topical agent you are using, or topical benzoyl peroxide at least for a while; taper it and see what happens. If you recur, chances are a topical agent will clear you; if not get with your physician. ...Read more

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I am on the antibiotic sulfamethoxazole-TMP for over eight months for acne. I've been having major loss of appetite, is this something to worry about?

I am on the antibiotic sulfamethoxazole-TMP for over eight months for acne. I've been having major loss of appetite, is this something to worry about?

Drug: May be a side effect of the drug. See your primary care for a complete checkup to look for other causes of weight loss. Call the dermatologist to see if there are other antibiotics you can take. Also be sure you are taking a probiotic to replace the bacteria of your intestine in case the weight loss is due to malabsorption from a change in the bacteria of the intestines ...Read more

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How long does it take to start seeing improvement in acne while using bactrim (sulfamethoxazole and trimethoprim) antibiotic?

How long does it take to start seeing improvement in acne while using bactrim (sulfamethoxazole and trimethoprim) antibiotic?

Weeks: Nothing works overnight for acne, except perhaps steroid injections into individual lesions.

You might get lucky and see improvement in just a week, but you should be prepared to give it 6 weeks. ...Read more

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Which of these antibiotics are better for treating dark acne spots on the face and why? (amoxicillin 500 mg capsule or sulfamethoxazole-tmp ds tablet)

Which of these antibiotics are better for treating dark acne spots on the face and why? (amoxicillin 500 mg capsule or sulfamethoxazole-tmp ds tablet)

Acne: Neither of those medications are useful for acne dark spots. Neither of them are very useful in treating acne at all. The sulfa drug can help acne but can have very serious side effects so it is not routinely used. Whenever the skin is inflamed it will get lighter or darker in color. See your dermatologist to get the acne under control so you don't get scars and dark spots. ...Read more

Dr. Tony Ho Dr. Ho
2 doctors agreed:
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Hi my derm gave me bactrim (sulfamethoxazole and trimethoprim) ds for my moderate but resistant acne how likely is this to cause steven jonson syndrome?

Dr. Tony Ho Dr. Ho
2 doctors agreed:
Hi my derm gave me bactrim (sulfamethoxazole and trimethoprim) ds for my moderate but resistant acne how likely is this to cause steven jonson syndrome?

Rare: Bactrim (sulfamethoxazole and trimethoprim) is associated with sjs, but it is still a very rare complication. Monitor for rash, and discontinue the medication and talk to your doctor if you develop a rash. Bactrim (sulfamethoxazole and trimethoprim) remains a very safe drug when used appropriately with thoughtful monitoring. ...Read more

Dr. J. Lawrence Dohan
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