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Doctor insights on: Succinylcholine Allergy

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What's succinylcholine allergy?

What's succinylcholine allergy?

Reaction to sux: In terms of allergy in the usual sense, it may not exist with succinylcholine. My top concern would be an adverse intrinsic response to exposure to this drug, called malignant hyperthermia. This is life threatening if not immediately recognized, there is genetic predisposition(family history). Other conditions preclude use of this drug too, renal failure, certain neurologic conditions as well. ...Read more

Dr. John Chiu
2,628 doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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What's succinylcholine allergy?

Reaction to sux: In terms of allergy in the usual sense, it may not exist with succinylcholine. My top concern would be an adverse intrinsic response to exposure to this drug, called malignant hyperthermia. This is life threatening if not immediately recognized, there is genetic predisposition(family history). Other conditions preclude use of this drug too, renal failure, certain neurologic conditions as well. ...Read more

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How serious is it if you have a succinylcholine family allergy?

How serious is it if you have a succinylcholine family allergy?

Important: I don't think you have a family "allergy" as much as a deficiency in the enzyme that breaks down succinylcholine, (pseudocholinesterase) which can occur quite commonly. It is IMPERATIVE that you tell your anesthesia provider this information. They can either use an alternative drug, or use succinylcholine and know that it would work longer. You can be tested to know if you have this problem. ...Read more

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What are things to know about succinylcholine?

Don't try at home.: Sux is a rapid acting short duration paralytic agent. Patient remains conscious but cannot move or breathe. Somewhat inhumane to use it without other agents. ...Read more

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Can succinylcholine kill you?

Can succinylcholine kill you?

Succinylcholine: Yes, succinylcholine without proper supervision and airway support can be deadly. Succinylcholine causes a temporary irreversibel binding of your muscles that relax the muscles including the respiratory muscles and can lead to death by lack of oxygen if a proper airway is not established and the patient is not supported with assisted breathing, it lasts 6-8 minutes but is very potent. ...Read more

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Can succinylcholine drugs decrease intraocular pressure?

Yes: Succinylcholine does increase intraocular pressures for about 20 minutes after administration. ...Read more

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I was curious as to a hypothetical situation of the side effects/symptoms of the succinylcholine chloride injection administered orally.

I was curious as to a hypothetical situation of the side effects/symptoms of the succinylcholine chloride injection administered orally.

Dangerous: This is a very potent drug that is given intravenously only. Using it orally there is some possibility of it being absorbed through your mucus membranes. It is really playing with danger to attempt oral administration. Death is one side effect. ...Read more

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Can etomidate and succinylcholine cause a positive etoh?

Can etomidate and succinylcholine cause a positive etoh?

Maybe: I am not aware of this. Etomidate comes in a 35% solution with propylene glycol which might give a false positive depending on the assay method, but this would not last long, would not likely be high and there would not likely be any concern of etoh intake around the time of etomidate or succ use. ...Read more

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Can etomidate and succinylcholine show up as a positive alcohol drug test?

Maybe: I am not aware of this. Etomidate comes in a 35% solution with propylene glycol which might give a false positive depending on the assay method, but this would not last long, would not likely be high and there would not likely be any concern of etoh intake around the time of etomidate or succ use. ...Read more

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What are the effects of administering succinylcholine?

What are the effects of administering succinylcholine?

Succ side effects: The effects of succinylcholine include whole body relaxation and paralysis used generally to calm combative or delirious patients who need to have a breathing tube placed for control of their airway or to undergo an operation. It can cause increased potassium from muscle spasm and twitching and can cause malignant hyperthermia rarely but this is very serious. Overall, it has a limited amt of uses. ...Read more

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Hi, I need a medical bracelet for being allergic to succinylcholine. What sort of information should I have engraved when I order my bracelet? Thx!

Hi, I need a medical bracelet for being allergic to succinylcholine. What sort of information should I have engraved when I order my bracelet?

Thx!

Just list it.: Your anesthesia would know what to do if you list it as an allergy even though it is an idiosyncratic reaction particular to you and many family members. ...Read more

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Would you use succinylcholine for an arthroscopic shoulder surgery?

Would you use succinylcholine for an arthroscopic shoulder surgery?

No i would not,: Succinylcholine is associated with too many side effects, some bothersome some lethal, and is too short acting. There are other better muscle relaxants available if necessary. ...Read more

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When administering Succinylcholine for intubation on a semi-conscious trauma pt with organophosphate poisoning, is there a dosage adjustment?

When administering Succinylcholine for intubation on a semi-conscious trauma pt with organophosphate poisoning, is there a dosage adjustment?

Shouldn't have to: The amount of Sch is overwhelming in an intubating dose. Also, Sch is a noncompetitive agonist, so it should work in a different mechanism than non-depolarizers.

"Semi-conscious?" — did you give an anesthetic, or does the patient look sedated b/c of the AchI effects? ...Read more

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Is it possible that succinylcholine drugs(nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure?

Is it possible that succinylcholine drugs(nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure?

No: Succinylcholine is known to increase intraocular minimally when given to secure the airway. The increase is small and passing, therefore it has been used in patients with increased intraocular pressure. ...Read more

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Can succinylcholine drugs (nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure? Any answers appreciated!

Can succinylcholine drugs (nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure? Any answers appreciated!

No.: Succinylcholine actually causes an increase in intraocular pressure for about 10 minutes after administration.
Classic teaching was not to use succ in people with open globe injuries. There are situations, though, where using succ with other agents that lower IOP is preferred because it makes intubation more smooth, avoiding hypertension and airway reactivity that is worse for the situation anyway ...Read more

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Dr. David Caro
120 doctors shared insights

Succinylcholine (Definition)

Succinylcholine is a neuromuscular blocker which is a ...Read more