Top
10
Doctor insights on: Sublingual Immunotherapy

Share
1

1
Is sublingual immunotherapy as effective as injections? I'm targeting fatigue that allergies cause. Living in Austin/TX it's almost year-round.

Is sublingual immunotherapy as effective as injections?  I'm targeting fatigue that allergies cause.  Living in Austin/TX it's almost year-round.

Overall shots better: When comparing sublingual vs subcutaneous immunotherapy, the latter turns out to be more effective overall. The fact that sublingual IT often causes oral itching and requires daily dosing leads to a very high drop-out rate. In addition, the allergens available for sublingual are quite limited- Dust mite may soon be approved but molds are likely many years away. ...Read more

See 1 more doctor answer
Dr. Michael Palumbo
1,122 doctors shared insights

Immunotherapy (Definition)

Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or ...Read more


2

2
When should immunotherapy be stopped?

When should immunotherapy be stopped?

When goals achieved: Immunotherapy is usually stopped when maximum benefit has been achieved (exception is stinging insect immunotherapy). The ideal goal is enough reduction in symptoms that only prn medications are required, but in some cases when no additional benefit is seen in symptom or medication reduction in the last year. ...Read more

See 1 more doctor answer
3

3
How is radio-immunotherapy administered?

How is radio-immunotherapy administered?

In steps: Radio-immunotherapy (rit) is given in three steps, all through an iv. Step 1: an antibody to b cells alone to clear out some normal b cells. Step 2: an antibody to b cells with a small amount of radiation attached, followed by imaging. Step 3: a "hot" antibody to b cells with a larger dose of radiation attached. This acts like a smart bomb to kill cancerous b cells (lymphoma cells). ...Read more

See 1 more doctor answer
4

4
When might immunotherapy be ineffective?

Immunotherapy: Never a guarantee any immunotherapy will be effective, but oftentimes it is due to making a weak serum, placing proteolytic allergens together, or patients non-compliance and never reaching top dose. ...Read more

See 1 more doctor answer
5

5
What is venom immunotherapy?

Bee or Wasp allergy: Venom includes bees wasps hornets and fire ants. Immunotherapy is a series of desensitization injections. Most often starting weekly and progressing to every 6 weeks in most cases. There are rush immunotherapy programs in place as well. Traditional immunotherapy continues for 5 years in most cases. ...Read more

See 1 more doctor answer
6

6
How does venom-immunotherapy work?

How does venom-immunotherapy work?

Venom Immunotherapy: If you have a history of anaphylaxis and confirmed venom allergy by skin testing, venom immunotherapy (VIT) can significantly reduce your risk of having a repeat systemic reaction in the future. With VIT risk of systemic reaction goes down to ~10% (general pop 3%). VIT alters your immune response. While not a cure, VIT significantly reduces your risk. Still need to carry EpiPen (epinephrine). ...Read more

7

7
Does immunotherapy involve antitoxins?

Definition: Immunotherapy indicates the use of immunological mechanisms for treatment. Allergy immunotherapy (allergy shots) do not include antitoxins. Antitoxins are antibodies against toxins and are used whaen toxins are suspected, for example posionous snake bites. This treatment can be called immunotherapy. ...Read more

See 1 more doctor answer
8

8
What is Antigen-specific immunotherapy?

What is Antigen-specific immunotherapy?

Specific allergens: If you are referring to allergy treatment, then this simply means that you are given extracts containing the specific allergens you are sensitized to. On the other hand, allergic people are usually less likely to have autoimmune diseases like rheumatoid arthritis which you appear to suffer. Thus you will need to tell us what disease condition this treatment is intended for. ...Read more

9

9
Is there an upper limit for immunotherapy?

No: There is no upper age limit for receiving immunotherapy. In considering immunotherapy in older persons, consideration must be given to the other medical conditions (such as cardiac disease) that are more frequent in older individuals, which could potentially make immunotherapy more risky. ...Read more

See 1 more doctor answer
10

10
How are chemotherapy and immunotherapy different?

How are chemotherapy and immunotherapy different?

See below: Chemotherapy involves drugs that are cytotoxic i.E destroy rapidly dividing cells (cancer cells); they are non-specific and not targeting any particular cancer biomarker. Immunotherapies on the other hand are of 2 types- 1] antibodies targeting certain biomarkers in cancer cells 2] treatments to boost patients immune response against the tumor. ...Read more

See 1 more doctor answer