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Subchondral Sclerosis Treatment
Are PRP and stem cell therapy txmt options for rapidly occurring Gr. 4 hip OA: superior joint impaction, subchondral sclerosis, joint fragments?
Stem cell treatment: Hi, please check Regenexx. Com.Get a more detailed answer ›
Need chronically: Some advice, there are pills available, but where you live, might be tough to get. Nonetheless, do not miss your injections, and add Vitamin D-3 about 5000-10000 units per day. We do not have a clear idea when to stop the MS meds, and in those older patients who I have stopped, a few have had relapses. Stay tuned, drugs to be used differently are on the horizon. (even Lemtrada)
Getting exciting: Original meds included self-injectables, such as betaseron, avonex, compaxone, and rebith. Later, tysabri (natalizumab) infusions, and 2 oral meds, Gilenya and aubagio. We now know that vitamin d supplements provide added benefit. No one med fits all, but most effective drugs currently are Gilenya and tysabri (natalizumab), and these work best of the current crop.
No unique answer: MS has many forms, many phases, individuals respond in all sorts of different and at times unpredictable ways so there is no BEST drug to tell you about. Latest research suggests the use of interferons and immunomodulating drugs is what best manages this disease. Unfortunately, there are plenty of problems with that approach but your doctor will discuss all the options with you.
All are permanent: All treatments for MS are not curative, in order to stop or slow down the progression of the disease, you have to take them indefnitely. I hope this answers your question, not sure what you mean by permanent. If you mean that the treatments "permanently" stop progression, only possibly if you keep using them. I like tysabri (natalizumab) despite the side effects. I see MS lesions literally disappear.See 1 more doctor answer
Complex: We do not know the exact cause of this autoimmune disease that attacks brain and spinal cord, but do find that both heredity and environment play roles in susceptibility. We are gaining new medicines which are far more potent (altho maybe risky), which can control the disease far better. The most potent available include tysabri (natalizumab) and gilenya. No cure yet, but stay tuned, it is close.
My opinion: For what it's worth, each ms patient is unique and not all meds fit each person. Yet, you want a potent effective medicine, and nowadays we have lots of choices. Must consider risks and side effects. Most effective meds in descending order would be tysabri, (natalizumab) gilenya, tecfidera, rebif, betaseron, aubagio, copaxone, and lastly avonex. No perfect med exists commercially..
Autoimmune: Ms is a disease where the immune system attacks the coverings of nerves in the brain and spinal cord. Susceptibility due to heredity and environment seem to affect who gets afflicted. The prognosis is improving dramatically these days due to new medicines. Therapies include tysabri, (natalizumab) gilenya, copaxone, betaseron, rebith, extavia, etc.
How can putting off treatment of multiple sclerosis by a few months after initial diagnosis (because of a temp. Loss of insurance) impact prognosis?
My experiences: Every MS patient is different, and experiences a varied and unique disease presentation, but we strongly suggest starting disease modifying agents as soon as diagnosis is confirmed to prevent disability. That said, delay of a few months may be trivial in your case, but, drug companies have programs for those without insurance, and no real reason to delay treatment. Discuss with your neurologist.See 1 more doctor answer
Not really: D-penicillamine might work, and there a number of studies suggesting this, but no long term double blind studies exist. A recent report suugest that a drug CellCept (mycophenolate mofetil) might be of value, and there are those that use mtx or tetracyclines. The major advances are ability to control BP and treat pulmonary hypertension. We can deal with esophgeal spasm and reflux. Nothing great at present for underlying dx.
Not curable: The disease is managed by surgery for the tumors as applicable, and medications. No two cases are alike. Ask about sirolimus if this question applies to a family member. Patients who wish to become parents will do well to learn how to prevent transmission of the illness to their children. Best wishes.See 1 more doctor answer
Degenerative Disease: The articular surfaces of the vertebrae become enlarge abnormaly and become stiff. The evidence suggests that best treatment is surgery by pedicle to pedicle decompression.
For someone who is 40 years old, what are the long term detrimental impacts of interferon treatment for multiple sclerosis?
Interferon: The real question you should be asking is "what are the detrimental effects of not taking interferon for treatment of ms". Ms can be a deadly disease and medications are chosen and recommended by physicians after a careful consideration of risks versus benefits. Ask the prescribing physicians for information that will help you look at both sides of this issue.See 2 more doctor answers
Not good: Lou gehrig's disease remains resistant to successful treatment or control. The drug Riluzole is on the market but is very disappointing, although may delay useage of a tracheostomy tube for a few months. We are learning about a misfolded protein, and this may point the way for future success.
Depends: For early stage disease, it's usually 2-4 cycles abvd w/ involved site radiation. For advanced disease, it's at least 4-6 cycles of abvd or even beacopp with radiation reserved for sites of bulk disease. For relapse, new drugs like Adcetris (brentuximab vedotin) are in use as are the option of transplant.
Yes: Systemic sclerosis is a slow progressive but relentless disease. Current treatments are of limited efficacy. Having said that, you should follow closely with a rheumatologist.
Try this: Although no cure currently, the drug Riluzole has been used to slow down the process and prevent or delay tracheostomy. Some pts might benefit from other glutamate blockers, Gabapentin and memantine have been tried in addition. Some alternative health sites have mentioned anti-oxidant approaches, and you might check hsi (health science institute). Get second opinion at nearby medical schools.
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