Doctor insights on:
Subacute Cutaneous Lupus Erythematosus Symptoms
Skin is the largest and one of most complex organs of body. 3 layers: epidermis (outer), dermis (main part) and subcutaneous layers covers entire body, contains many specialized cells, maintains body temp, gathers sensory info from the outer world, has extremely important immune functions. It can give crucial clues as to what is internal. Dermatology and plastic surgery are ...Read more
Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read moreSee 1 more doctor answer
Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read moreSee 1 more doctor answer
SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more
Rash: There are different types of subacute cutaneous lupus (scle) - a characteristic form has lesions that may have an annular configuration, with raised red borders and central clearing. A second type of scle has psoriasis-like lesions with red scaly patches on the arms, shoulders, neck, and trunk and fewer patches on the face. This rash is characteristically made worse by sunshine - photosensitive. ...Read more
Many: People with lupus may have joint pain, skin rashes, chest pain, heart probelms, hair loss, fingers changing color in the cold, rash in the sunshine, neuro-psychologic problems. These are only soemof the symtpoms peopel can have. They can also have none of these. Your physician will evaluate all of these, get labs tests and imaging. ...Read moreSee 1 more doctor answer
Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more
Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read moreSee 1 more doctor answer
Biopsy, blood test: Rashes are not always easy to diagnose. Simple acne or severe plaque psoriasis may not require further tests to diagnose the condition. In scle, the rash may require a biopsy which is the very best test. Blood tests may reveal a positive antinuclear antibody (ANA) and a positive ssa antibody. ...Read more
Does chronic cutaneous discoid lupus eryhermyosolus turn systemic if you have positive ANA 1:1280 normally.
This is an autoimmune disease which is exacerbated by sun exposure. It includes a rash on sun exposed areas such as the face, chest, and arms. It may be seen in Inc. his and in adults. It is often associated with abnormal immunology studies such as an SSA and SSB autoantibodies. The treatment differs versus on the severity of the skin lesions and includes both ...Read more
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