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Doctor insights on: Strongest Scleroderma

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What makes systemic scleroderma flare?

What makes systemic scleroderma flare?

Stress: There are no specific triggers to avoid if you have the condition. However, internal or external stress often precede a flare of scleroderma. ...Read more

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Dr. Pierre Moeser
185 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect ...Read more


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Is scleroderma genetic?

Is scleroderma genetic?

Yes: In certain groups such as the choctaw population in oklahoma there is a strong genetic component. There is also a difference in populations between the different continents. ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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What are the differences between lichen planus (lpp)& lupus erythematosus (le)?

What are the differences between lichen planus (lpp)& lupus erythematosus (le)?

Skin vs systemic: Lichen plan us is a skin and mucous membrane (mouth) disease. There are several forms of lupus. Some forms affect only the skin and can even look like lichen planus skin changes. The main firm (SLE) is a systemic total body, autoimmune disease not limited to the skin and mouth. Lupus Erythematosis is also associated with lab abnormalities not present in lichen planus ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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What is the strongest systemic antifungal?

What is the strongest systemic antifungal?

Amphotericin B: Different antifungals are used for different fungal infections. The more potent may cause the worse side-effects. So for antifungals more potent is not necessarily better. Simple antifungals for simple infections, stronger and potentially more dangerous antifungals for life threatening infections. ...Read more

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What is the difference between drug-induced lupus & systemic lupus? 

Very different : There are differences - especially less kidney involvement, different serology to name some things . It mostly resolves after stopping the drug involved. ...Read more

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Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?

Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?

Impossible to say: It depends on the severity of each disease. Psoriatic would be considered the most benign. ...Read more

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What is the best climate for me. I have lupus scleroderma RA fibromyalgia and crest syndrome ?

What is the best climate for me. I have lupus scleroderma RA fibromyalgia and crest syndrome ?

The Mighty Vitamin D: You may do better in warmer climate closer tot he equator for 2 reasons: more vitamin D and more exercise . Receiving more sunlight would naturally raise your vitamin D levels. Adequate vitamin D is essential for fibromyalgia relief, and is a powerful anti-inflammatory.More exercise, especially light walking or yoga on the beach would add to the benefit of vitamin D. ...Read more

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What is the difference between psoriatic arthritis and spondyloarthrapathy? I'm hla b-27 positive

What is the difference between psoriatic arthritis and spondyloarthrapathy? I'm hla b-27 positive

Almost the same: Many people with psoriatic arthritiw have back problems similar to classic ankylosing spondylitis. The meds used for these are the same and include sulfasalazine, methotrexate, biologics including humira, remicade, (infliximab) etc. Occasionally the arthritis goes into remission (stops) if the skin is cleared, but this isn't common. Nonsteroids such as indomethecin are quite helpful. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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How to tell the difference between systemic lupus erythematosus or rheumatoid arthritis?

How to tell the difference between systemic lupus erythematosus or rheumatoid arthritis?

Sometimes hard: Both have arthritis as part of the disease in RA it is the major feature and most people have nothing else. Lupus, while having arthritis as part of it, often has many other features of other organ systems like the skin kidneys bervous system or blood best way is to see a rheumatologist. ...Read more

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Does kid qualify for vaccine exempt with family hist of scleroderma, Raynaud's, psoriasis, scoriatic arthritis, and personal hist of eczema and celiac?

Does kid qualify for vaccine exempt with family hist of scleroderma, Raynaud's, psoriasis, scoriatic arthritis, and personal hist of eczema and celiac?

No: Vaccines will prevent you from getting serious diseases which might complicate your personal history of eczema and celiac disease. Go see your Pediatrician and get all protections you can. ...Read more

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Please help! what is the difference between lichen planus (lpp)& lupus erythematosus (le)?

Please help! what is the difference between lichen planus (lpp)& lupus erythematosus (le)?

Difference: Lp no cure, cause unknown, not understood well by medicine. Le is an autoimmune disease, no cure, treatment is to treat the symptoms with drug therapy. Please consult your md. ...Read more

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Any one familiar with mctd, specifically morphea and lichen sclerosis?

Any one familiar with mctd, specifically morphea and  lichen sclerosis?

Lichen Sclerosus: Corticosteroid ointments or creams are commonly prescribed for lichen sclerosus. Initially, you'll generally have to use cortisone creams or ointments on the affected skin daily. After several weeks, your doctor will likely recommend that you only use these medications twice a week to prevent a recurrence. Your doctor will monitor you for side effects associated with prolonged use. ...Read more

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Dr. Tiffanie Noonan
144 doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more