Top
10
Doctor insights on: Stopping Zofran

Share
1

1
If Zofran (ondansetron) caused QTc prolongation, would QT int. go back to normal after stopping the medication? Or is this a permanent change?

If Zofran (ondansetron) caused QTc prolongation, would QT int. go back to normal after stopping the medication? Or is this a permanent change?

BACK TO NORMAL: Ondansetron (Zofran) primarily blocks potassium channels, prolonging the QT interval, but these changes are acute, transient and reversible. Concern was for IV formulation in doses higher than 16 mg. ...Read more

Dr. James Henning
402 doctors shared insights

Ondansetron (Definition)

Ondansetron is a nausea and vomiting agent which is a ...Read more


2

2
Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (i took one dose) does the risk for cardiac issues cease?

Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (i took one dose) does the risk for cardiac issues cease?

Ondansetron: Zofran (ondansetron) in doses greater than 16 mg at a time has been implicated in prolonging the qt interval. This effect would last for a few hours while the drug was in the system. A single 4 mg dose does not carry this risk. ...Read more

3

3
What are some medicines to stop nausea? I tried Zofran (ondansetron) but it doesn't work.

see details: Has the problem been thoroughly evaluated medically? Have you seen a gastroenterologist? Establish the cause first. ...Read more

4

4
Does Zofran (ondansetron) cause withdrawal symptoms if you stop taking it after being on it for 20 months?

Zofran (ondansetron) for nausea: If you stop a medicine for nausea, most likely you will experience a rebound effect after stopping the medication. Zofran (ondansetron) does not produce tolerance, therefore there will be not discontinuation syndrome or physical withdrawal if not taken anymore. Hopefully the cause for the nausea has disappeared and stopping zofran (ondansetron) will not cause any problems. ...Read more

5

5
I've been taking zofran for about 2 years because lexapro (escitalopram) makes me sick. Can I stop zofran or do I have to taper off? 4mg 2x's a day. How do I taper?

I've been taking zofran for about 2 years because lexapro (escitalopram) makes me sick. Can I stop zofran or do I have to taper off? 4mg 2x's a day. How do I taper?

Lexapro (escitalopram) : Should be tapered to minimize withdrawal symptoms. Sometimes switching to low dose Prozac (fluoxetine) helps with the discontinuation symptoms. Any change in antidepressant therapy should've done under physician supervision. ...Read more

See 1 more doctor answer
6

6
How long does Buspar (buspirone) 5 mg 3xs day stay in your system. my last does was last night i only took for 6 days. my dr said to stop. when can i take zofran

How long does Buspar (buspirone) 5 mg 3xs day stay in your system. my last does was last night i only took for 6 days. my dr said to stop. when can i take zofran

Buspar/clearance: Under ordinary circumstances, the Buspirone should clear in 12-24 hrs, although traces could be detected in urine (if we could test). I don't believe there would be any interference if you are or not on Zofran (ondansetron). ...Read more

7

7
Took Zofran (ondansetron) and had temp blurred vision but it went away. What usually causes the blurred vision, and if it went away and I stop meds, should I worry?

Took Zofran (ondansetron) and had temp blurred vision but it went away. What usually causes the blurred vision, and if it went away and I stop meds, should I worry?

Possible drug effect: While blurred vision is not a listed side effect of Zofran (ondansetron), (ondansetron) uncommon side-effects can occur with any medicine. The fact that the blurred vision went away when you stopped the drug suggests that the drug caused it. The only way to prove that would be to restart Zofran (ondansetron) and see if it recurs. The best recommendation is to avoid Zofran (ondansetron) altogether. ...Read more

8

8
Does zofran (ondansetron) stop nausea from panic attacks?

Does zofran (ondansetron) stop nausea from panic attacks?

It can: yes, the medication can short-circuit nausea and vomiting due to panic attacks. Better solution might be to reduce the panic attacks themselves either entirely or by intensity and frequency. Then, Zofran (ondansetron) becomes a non-issue. ...Read more

See 2 more doctor answers
9

9
Does zofran (ondansetron) stop/prevent all nausea? I.e. reflux, medications, virus, etc.

Does zofran (ondansetron) stop/prevent all nausea? I.e. reflux, medications, virus, etc.

Not really: It was originally used for vomiting induced by chemotherapy and anesthesia, but has become widely used for all types of vomiting including vomiting in pregnancy. No drug is 100% effective and failure rates in studies are as high as 25-30%. Thanks for trusting HealthTap! ...Read more

See 1 more doctor answer
Dr. Zahid Niazi
309 doctors shared insights

Zofran (Definition)

Zofran is a nausea and vomiting agent which is a ...Read more