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Doctor insights on: Stopping Prilosec

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Dr. Tri Huynh
838 Doctors shared insights

Omeprazole (Definition)

Omeprazole is the generic equivalent of prilosec, the first oral acid-reducer agent of the proton pump inhibitor ...Read more


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Besides acid reflux, are there side effects of stopping prilosec? Specifically related to bowel changes?

Definitely: Will cause increase in acid production. So will get more reflux symptoms than you used to have. This is called a rebound effect after stopping the med. I would titrate it down slowly. To avoid too much of an issue. It will regulate over time. May cause some GI upset mild loose stools but no long term effects

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Been taking prilosec for about a year for acid reflux. I was thinking about stopping and seeing whether it comes back or not. Is this a good/bad idea?

Been taking prilosec for about a year for acid reflux. I was thinking about stopping and seeing whether it comes back or not. Is this a good/bad idea?

Acid reflux.: Most people with acid reflux require long-term medication, but if you're doing exceptionally well, it may be worth a trial of stopping it to see how you do. I would follow anti-reflux precautions well, and use antacids such as Tums (calcium carbonate) whenever you feel acid reflux. If your symptoms recur more than 3x per week, you probably need to be back on the medicine. I would discuss this with your G.I doc prior.

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Could Prilosec cause changes in metabolism. I took prilosec for a few days and gained 3 pounds, I've decided to stop taking it. Will I still gain weig?

Could Prilosec cause changes in metabolism. I took prilosec for a few days and gained 3 pounds, I've decided to stop taking it. Will I still gain weig?

NO IT DOES NOT: Prilosec simply took care of what ever upsetting your stomach so you can eat better, you end up eating more, do not blame it on the pill, blame your appetite. if you want to lose weight, eat healthy, exercise, count your calories.

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How can I stop acid reflux without using Prilosec or anything similar?

Many choices of RX: Acid reflux is a chronic condition in most people. So it requires a change in lifestyle and medication to relieve symptoms. Your gastroenterologist can help you for the long term control. But there are many antacids of varying potencies and different costs which can stop the acid production like Pepcid or zantac (ranitidine) or neutralize acid like with mylanta or gelusil. Avid aspirin/advil / coffee and alcoh.

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If I stop taking my Prilosec will my gastrin levels return to normal permanently?

No: I am going to assume you've been found to have an elevated gastrin level and this is causing you to make extra stomach acid. The Prilosec will help protect your stomach from the gastrin. This isn't a forum to evaluate a complete history, but if you have a gastrinoma, there are often additional ways to manage it though Prilosec is a good start. Stay proactive and good luck.

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Can I stop taking Prilosec after 7 days? Today is the fourth day of treatment and I don't have any symptom.

What R U treating?: If your goal of taking Prilosec was symptom relief, then the drug can be discontinued when no longer needed. However, if Prilosec was dispensed to therapeutically heal a damaged esophagus and stomach, then you are a long way from, but on your way to, cure based on symptom-response.

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Endo showed many sessile polyps 3-6mm in size, been taking Prilosec yrs, should I stop, how can I stop without bad flare? Please scared of this all!

Endo showed many sessile polyps 3-6mm in size, been taking Prilosec yrs, should I stop, how can I stop without bad flare? Please scared of this all!

Polyps: Are not a reason to discontinue taking Prilosec. If polyps are found by colonoscopy are in the colon then hopefully one of the polyps was biopsied and found to be benign. If that is the case, then follow up colonoscopy should be done within the recommended follow up time. Prilosec should not affect polyps in the lower intestinal tract and if anything should be helpful for the upper GI tract.

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I've been taking 20 mg of celexa (citalopram) for 3 days at night and Prilosec in the morning. Am I trouble this soon or will I be good if I stop one of them now?

I've been taking 20 mg of celexa (citalopram) for 3 days at night and Prilosec in the morning. Am I trouble this soon or will I be good if I stop one of them now?

Need doctor's advice: Never alter the total dose, duration, frequency of daily use, nor start/stop a prescription drug without your doctor's advice. We don't know you or what's being treated here. Stop second guessing your doctor! Address your question appropriately to your prescribing provider who not only knows your health history but also what medications are or are not needed for your problem (s).

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When you take Prilosec it changes the flora in your gut. If you stop taking Prilosec does the flora in your gut go back to how it was before?

When you take Prilosec it changes the flora in your gut. If you stop taking Prilosec does the flora in your gut go back to how it was before?

Bacterial overgrowth: In the stomach and duodenum has UNKNOWN clinical significance in health people. This effect has only been described in very ill Intesive Care Unit patients. This change in bacterial population quickly reverses when the proton -pump inhibitor (egf Prilosec) is discontinued! Hope this helps! Dr Z

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Upper endo many sessile polyps3-6mm. Been on Prilosec yrs. Should I stop Prilosec? Sessile polyps mean cancer?

Upper endo many sessile polyps3-6mm. Been on Prilosec yrs. Should I stop Prilosec? Sessile polyps mean cancer?

Fundic gland polyps: These types of polyps in the fundus of the stomach are of no real concern. They do not increase the chances of cancer. They are not a reason to stop your Prilosec, if you need it. Your endoscopist will be able to follow up with you concerning them. Good luck.

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I have been taking a half a Prilosec for years. Is it harmful? If I stop, within a few days I have really bad heartburn.

Maybe: Maybe ask why do you have more acid? Often when pancreas doesn't produce sufficient enzymes to digest food then stomach secretes more acid to "make up" causing heartburn. Acid is needed to absorb many nutrients among other important functions god intended. Long term suppression is not good. Try some good digestive enzymes with meals and then try to taper Prilosec for long term health preservation.

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Upper endo multi gastric polyps 3-6mm all were benign, Prilosec cause them, should stop Prilosec, or ok keep taking, On Prilosec 10+yrs, scared risks?

Upper endo multi gastric polyps 3-6mm all were benign, Prilosec cause them, should stop Prilosec, or ok keep taking, On Prilosec 10+yrs, scared risks?

Abs: Well interesting question the proton pump inhibitors as well as the h2 blockers were designed to be used up to 8 was. Most people who start them stay on them forever this was not the intended use. You have to modify your lifestyle in other words eat better and exercise. Get rid of all that junk food and soda erc. Eat a healthy lifestyle protein fruits and vegetables and exercise everyday.

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My dr. Told me to stop prilosec due to colitis. How long does rebound effect last. I never had heartburn like this before. How can I treat naturally?

My dr. Told me to stop prilosec due to colitis. How long does rebound effect last. I never had heartburn like this before. How can I treat naturally?

It's tough: And I wonder if your doctor will allow the use of H-2 Blocker like PEPCID (famotidine) or TAGAMET Ask! Hope this helps BTW LACTAID FREE MILK may help. And its almost "natural" (I assume with colitis you may be lactase Deficient)

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I had my GS surgery on May 2013 last summer I started burping non stop even early in the morning before I eat anything I'm on Prilosec for the last 7M?

I had my GS surgery on May 2013 last summer I started burping non stop even early in the morning before I eat anything I'm on Prilosec for the last 7M?

Is GS: Gastric surgery bypass? If so what you are doing maybe of some importance. This may be related to carbonated drink, caffeine, stress, air swallower or possible food intake that causes gas? See your doctor advice in the meantime look at what you are eating or drinking as this may have a lot to do with it.

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Been on prilosec for 3yrs. I have osteopenia & want to stop. Can I stop cold turkey? Doctor not much help! Any adive would be great! Thanks

No withdrawal: There is no withdrawal from prilosec, but whether you should stop cold turkey or gradually taper depends on the reason for taking it. It's always a good idea to reduce dosage of a long-term medication before stopping completely.

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Upper endo found lots 3-6mm Gastric Fundic Polyps, on Prilosec years, read PPI cause of them, should I stop, how to step down off it?

Upper endo found lots 3-6mm Gastric Fundic Polyps, on Prilosec years, read PPI cause of them, should I stop, how to step down off it?

Fundic gland polyps: These types of polyps in the fundus of the stomach are of no real concern. They do not increase the chances of cancer. They are not a reason to stop your Prilosec, if you need it. Your endoscopist will be able to follow up with you concerning them. Good luck.

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Can fundic gland polyps turn into cancer? I have many in my stomach 3-6mm cause by long term use of Prilosec. Should I stop taking it.

Can fundic gland polyps turn into cancer? I have many in my stomach 3-6mm cause by long term use of Prilosec. Should I stop taking it.

Not clear: That is a good question. At present time we do not have evidence of this although some studies have suggested possible relationship with stomach cancer, but I would not stop sur to the finding of polyps. If you are taking for reflux why not consider an anti reflux procedure?