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Doctor insights on: Stopping Lupron

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How long after stopping lupron (leuprolide) for endometriosis will it take for your body to go back to normal?

How long after stopping lupron (leuprolide) for endometriosis will it take for your body to go back to normal?

Few days: Even though half life of Lupron (leuprolide) is only 3 to 4 hrs plasama levels will remain high for few more days ( missing one dose is not a big problem ). ...Read more

Dr. Corey Clay
150 doctors shared insights

Leuprolide Acetate (Definition)

Leuprolide acetate is a GnRH stimulator which is a kind of women's ...Read more


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When should lupron (leuprolide) be used to treat ovarian cysts? I have a functional & complex - keep growing and bc not stopping new cysts

When should lupron (leuprolide) be used to treat ovarian cysts? I have a functional & complex - keep growing and bc not stopping new cysts

It kind of: Depends on your symptoms. Are you in pain? Are the cysts large? Do you have endometriosis or pain? The medicine is not a cake walk in that it is expensive and will places into menopause with all the drawbacks. It may not resolve the cysts either. I am suprised they enlarge on the ocp. How long have u been on them? ...Read more

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I was given Provera 2x a day (08/01 to 08/26) to stop bleeding eventhough I had Lupron shot last 06/26. Any bad effects of long term use of Provera?

I was given Provera 2x a day (08/01 to 08/26) to stop bleeding eventhough I had Lupron shot last 06/26. Any bad effects of long term use of Provera?

Provera: Provera can be used safely for various times depending on what problem is being addressed. Since you have been treated with Lupron and Provera it sounds like your issue may be fairly complex. Consider scheduling follow up with your Obgyn to clarify the diagnosis, the treatment plan and the time line for treatment ...Read more

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Skin is breaking out really badly ever since i had a surgery and this is my second injection of the lupron (leuprolide) shot. What can I do to stop the breakouts?

Skin is breaking out really badly ever since i had a surgery and this is my second injection of the lupron (leuprolide) shot. What can I do to stop the breakouts?

Medical Treatment: Breakouts should be treated by dermatology. You may start with over-the-counter topical cleasner (benzoyl peroxide 5%) but you will eventually need prescription medications such as tretinoin cream, topical and oral antibiotics. Your dermatologist will determine the appropriate combination of medications. ...Read more

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Can lupron (leuprolide) stop menstruation one month after injection?

Can lupron (leuprolide) stop menstruation one month after injection?

Yes: Lupron (leuprolide) induces temporary menopause. It lasts about a month and then the ovaries start working normally again. Hormone levels will then slowly get back to normal. ...Read more

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I had D&C on 06/25 and was given Lupron that my OB said is good for 3mos. I have AUB from 06/10 until I was given provera on 07/08. I am bleeding again since 07/21. OB gave hemostan and if bleeding wont stop, will go back to her. Why do I have AUB?

I had D&C on 06/25 and was given Lupron that my OB said is good for 3mos. I have AUB from 06/10 until I was given provera on 07/08. I am bleeding again since 07/21. OB gave hemostan and if bleeding wont stop, will go back to her. Why do I have AUB?

Hard to say: The amount of information given is not enough without an examination, a full history, and pathology report results of the D & C to give an accurate cause of the abnormal uterine bleeding. Talk to your OB MD and ask pointed questions as needed or obtain a 2nd GYN MD opinion/consultation. ...Read more

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Does Lupron (leuprolide) for treatment of prostate cancer, also stop the formation of seminal liquid.

Does Lupron (leuprolide) for treatment of prostate cancer, also stop the formation of seminal liquid.

Slightly Possible: The vast majority of Lupron (leuprolide) users have no reported decrease in seminal fluid. Those that do report a decrease were mostly >60 yrs old. ...Read more

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What does lupron (leuprolide) do?

What does lupron (leuprolide) do?

Hormone inhibitor: Lupron (aka leuprolide) inhibits the production of testosterone and estrogen from the testes and ovaries, respectively. It is used in the treatment of a number of things including endometriosis, prostate and breast cancer and inappropriately early puberty in kiddos, each of which is made worse by excessive testosterone or estrogen secretion. ...Read more

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What are side affects of lupron (leuprolide)?

What are side affects of lupron (leuprolide)?

Menopausal effects: Lupron (leuprolide) injections are used for many reasons in gynecology, most commonly in the treatment of fibroids and endometriosis. Essentially, Lupron (leuprolide) shuts down ovarian function and leads to a menopausal state. Therefore, side effects include hot flashes, vaginal dryness, mood swings, decreased libido, and bone loss. ...Read more

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How long does one lupron (leuprolide) shot last?

How long does one lupron (leuprolide) shot last?

Depends: Leuprolide acetate is available in two long-acting formulations as Lupron (leuprolide) depot. It is available in a 1-month and a 3-month version. Microdose Lupron (leuprolide) as used for ivf is generally very short acting, but the pharmacology is too complex to explain here. ...Read more

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What was your experience with lupron (leuprolide)?

What was your experience with lupron (leuprolide)?

Depends/ indications: I agree with the prior answer in context, but want to weigh in on other uses. Studies show Lupron (leuprolide) in the depot form is effective at shrinking fibroid volume by about 1/3 in 3 months. This gives a proven statistically lower blood loss in women preparing for surgical myomectomy. Also Lupron (leuprolide) in the non-depot form is safe, effective and routinely used in stimulations for ivf. ...Read more

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Complcations with long use of lupron (leuprolide)?

Complcations with long use of lupron (leuprolide)?

Yes: Long term use of Lupron can weaken the bone. Anyone on long term Lupron should be on add back therapy to prevent bone loss as well as calcium and vitamin d. Long term Lupron can also predispose to heart disease and so estrogen add back should be considered to prevent this risk. ...Read more

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Are there symptoms associated with lupron (leuprolide) ?

Are there symptoms associated with lupron (leuprolide) ?

None serious.: There are no known serious side effects from the Lupron (leuprolide) trigger. Some mild side-effects might include: hot flashes, vaginal dryness, and headaches. ...Read more

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Can you tell me about taking lupron (leuprolide) shot in my 30's?

Can you tell me about taking lupron (leuprolide) shot in my 30's?

Endometriosis: Lupron is a powerful suppressor of estrogen activity (mediated through the hypothalamus and pituitary), and it is used to suppress symptoms of endometriosis. It has many side effects including hot flashes and bone loss.

Many doctors use this but I do not. It is my professional opinion (and profession) that women with endometriosis would benefit more from expert excision of their disease. ...Read more

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Why do we have to take lupron (leuprolide) and norethidrone together?

Why do we have to take lupron (leuprolide) and norethidrone together?

Add back therapy: Lupron (leuprolide) acts on the pituitary to shut down production of hormones such as estrogen. This can lead to side effects such as hot flashes and bone loss. Adding back some hormones, in this case progestin, can help ameliorate these symptoms. ...Read more

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What should happen when my last dose of lupron (leuprolide) wears off?

What should happen when my last dose of lupron (leuprolide) wears off?

After Lupron (leuprolide): A 3.75 lupron (leuprolide) depot dose well generally take a while to wear off. After 4 weeks, the dose should be gone and your would start growing a follicle for the next cycle, if you have regular cycles. Expect a subsequent period about 6-8 weeks after the last injection. The hot flashes usually subside about 4-6 weeks after the last injection. The more doses you have receive, the longer it may take. ...Read more

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How long does it take fo the effects of lupron (leuprolide) to wear off?

How long does it take fo the effects of lupron (leuprolide) to wear off?

Varies: There are three forms of lupron, (leuprolide) one is a subcutaneous injection daily which will wear off very quickly. The second type is a depot form which last for approximately 30 days in the body, and lastly there is a 90 day form. A woman will usually ovulate 2 to 4 weeks after the effects of the Lupron (leuprolide) has worn off. ...Read more

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My husband has been on lupron (leuprolide) x 3 years how long can he take this drug?

My husband has been on lupron (leuprolide) x 3 years how long can he take this drug?

No time limit: It really depends upon its benefit to your husband. Men with metastatic disease can have long term benefit. ...Read more

Dr. AARATHI Cholkeri-Singh
160 doctors shared insights

Lupron (Definition)

Lupron is a GnRH stimulator which is a kind of women's ...Read more