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Doctor insights on: Stevens Johnson Syndrome Lamotrigine

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What's stevens johnson syndrome?

What's stevens johnson syndrome?

Severe reaction: Stevens johnson syndrome (sjs) is a severe immune reaction, usually to a medication. It can present with rash that leads to sloughing (peeling off) of the skin and mucous membranes (e.g., inside the mouth or vagina). It can also cause fever and damage to internal organs. Urgent treatment by qualified medical professionals is extremely important. See your doctor if you have further questions. ...Read more

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Dr. Emily Altman
107 doctors shared insights

Stevens Johnson Syndrome (Definition)

A rare, serious disorder of the skin and mucous membranes. It's usually a reaction to a medication or an infection that typically begins with flu-like symptoms followed by a painful red or purplish rash ...Read more


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Is steven johnson syndrome contagious?

Is steven johnson syndrome contagious?

No: Stj syndrome is the most severe form of (em) erythema multiforme. Em is a hypersensitivity reaction that occurs in response to meds, infections, or illnesses. Exact cause is unknown but thought to be related to damage to blood vessels of skin then tissue damage. Em minor is caused usually by herpes simplex or mycoplasma. Em major (stj) is usually caused by medications. Stj can be deadly! ...Read more

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Compare steven johnson syndrome/erythema multiforme?

Compare steven johnson syndrome/erythema multiforme?

Degree: Erythema multiforme is an allergic skin condition usually due to a medication or an infection. It may be mild but can also have a severe life-threatening form called erythema multiforme major or stevens-johnson syndrome. ...Read more

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What is steven johnson syndrome?

What is steven johnson syndrome?

SJS: Stevens-johnson syndrome is a rare, serious disorder in which your skin and mucous membranes react severely to a medication or infection. Often, stevens-johnson syndrome begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters, eventually causing the top layer of your skin to die and shed. ...Read more

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Can stevens johnson syndrome be cured?

Yes, sometimes: Depending on a number of factors, stevens johnson syndrome can be treated once the offending agent can be removed from the body and the immune system can be quelled and the patient protected from infection, dehydration, and multi-organ failure. ...Read more

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Can stevens johnson syndrome be treated?

SJS: Absolutely. Sjs is best treated in a burn unit by trained professionals. It is all patient dependent since there are differing views on the use of corticosteroids. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001854/. ...Read more

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How safe is rifampicin with steven johnson's syndrome?

Depends on prior med: The currently worded question can.t be answered without knowing what the Steven-Johnson's syndrome reaction to what? If it was to a medication with the same or similar chemical structure as rifampicin, then it's not safe. If caused by a completely different medicine, then it's safe. ...Read more

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How do barbiturates cause steven johnson syndrome?

Stevens-Johnson : Sjs is an immune mediated reaction where your body is tricked into thinking of itself as the enemy. Some people have livers that can't metabolize barbiturates well, they are "slow acetylators". This leads to an accumulation of metabolite byproducts that may bind to normal tissue ("haptens") and trigger a destructive immune response against the skin ("keratinocytes" in the "epidermis"). ...Read more

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What are toxic epidermal necrolosys/steven johnson syndrome/erythema multiforme"?

What are toxic epidermal necrolosys/steven johnson syndrome/erythema multiforme"?

Serious Problem: Ten (toxic epidermal necrolysis) and (sjs) steven johnson syndrome are the same illness and only are separated by the percentage of body surface area involved. Erythema multiform is usually a much more limited problem. Ten/sjs can be caused by many things, and results in sloughing off of the skin in large areas and can cause severe infection, fluid loss and death. ...Read more

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Can MRSA change into stevens johnson syndrome?

Can MRSA change into stevens johnson syndrome?

NO: Mrsa is caused by methcillin-resistant staphylococcus aureus, a bacteria that can cause serious infections and is resistant to a number of antibiotics. Stevens-johnson syndrome (sjs) is completely different. Sjs refers to a very serious, life-threatening allergic reaction to a drug (such as an antibiotic) that can lead to the sloughing off of the superficial layer of skin and mucous membranes. ...Read more

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How healthy is rifampicin from steven johnson's syndrome?

Not good : There is no history here but with stevens Johnson this is not good. This can be a cause of stevens Johnson. At a time with the disease is active the liver is under a lot of stress . It would be better to avoid. ...Read more

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What is stevens johnson syndrome pictures would help?

What is stevens johnson syndrome pictures would help?

Stevens-Johnson: Stevens-johnson syndrome is a rare, serious disorder in which your skin and mucous membranes react severely to a medication or infection. Often, stevens-johnson syndrome begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters, eventually causing the top layer of your skin to die and shed. ...Read more

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What is stevens-johnson syndrome?

See details: This is a very rare but very serious and even life threatening disorder of the skin and mucous membranes. It is usually a reaction to a medication or an infection. It usually begins with flu-like symptoms followed by a painful rash in which the top layer of the skin dies and sheds. It is an extreme emergency and requires immediate hospitalization. ...Read more

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What is steven-johnson syndrome?

Drug reaction: One of the most severe and life-threatening forms of drug reactions. Patients peel off their skin and may need to be treated in the burn unit. ...Read more

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How are johnson syndrome and toxic epidermal necrolysis related?

How are johnson syndrome and toxic epidermal necrolysis related?

Similar: They are similar but stevens johnson syndrome affects mucous membranes on eyes and mouth. Both are usually caused by reaction to medication but cancer and infections can be triggers also. ...Read more

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I need information about steven johnson syndrome, and erythema multiforme.?

I need information about steven johnson syndrome, and erythema multiforme.?

See below : Stj syndrome is the most severe form of (em) erythema multiforme. Em is a hypersensitivity reaction that occurs in response to meds, infections, or illnesses. Exact cause is unknown but thought to be related to damage to blood vessels of skin then tissue damage. Em minor is caused usually by herpes simplex or mycoplasma. Em major (stj) is usually caused by medications. Stj can be deadly! ...Read more

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In the past I used Lamotrigine without problems. Considering this, what are the chances of me getting the Stevens-Johnson Syndrome if I continue to use it in the long term?

In the past I used Lamotrigine without problems. Considering this, what are the chances of me getting the Stevens-Johnson Syndrome if I continue to use it in the long term?

Just watch yourself: At the first sign of a rash, discontinue it and get seen. This should prevent the rash from turning into full-blown Stevens-Johnson. ...Read more

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I was prescribed Lamictal today; I have Eczema. How will I know the difference between and Stevens-Johnson Syndrome? Do I have to go to the ER?

I was prescribed Lamictal today; I have Eczema. How will I know the difference between and Stevens-Johnson Syndrome? Do I have to go to the ER?

You'll know: I'm very glad you're taking a proactive approach to your health. You're familiar with your eczema; the rashes that herald the dread, uncommon complication of lamotregine toxicity will be different. Many people need a medicine like this to help with the difficulties of life today and/or the chemistry of our brain, especially as we are learning new ways of acting and thinking. Stay on top of it. ...Read more

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Can stevens johnson syndrome be cured?

Yes, sometimes: Depending on a number of factors, stevens johnson syndrome can be treated once the offending agent can be removed from the body and the immune system can be quelled and the patient protected from infection, dehydration, and multi-organ failure. ...Read more

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Can you die of stevens-johnson syndrome?

Can you die of stevens-johnson syndrome?

Yes, SJS is serious: Stevens johnson syndrome (eryth. Multi. Major, ten) is a rare but sometimes fatal allergic reaction. A person can have fever, malaise (general discomfort), skin itching, joint aches, and a fairly rapid appearance of reddened spots or patches all over. The rash can have "target" or "bulls-eye" spots, and even blisters. Eye irritation can occur, as well as sores on eyelids, lips, and in the mouth. ...Read more

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Can stevens johnson syndrome be treated?

SJS: Absolutely. Sjs is best treated in a burn unit by trained professionals. It is all patient dependent since there are differing views on the use of corticosteroids. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001854/. ...Read more

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Can you die from stevens johnson syndrome?

Can you die from stevens johnson syndrome?

Yes: Stevens johnson is a very serious immune reaction manifest as skin and mucosal damage and sloughing. It looks similar to and has effects like a burn. Untreated one can die of dehydration and infection. ...Read more

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What are the tests for stevens johnson syndrome?

BIopsy confirms: Stevens-johnson is such a severe and obvious disease of the skin, and often eyes and mucosal surfaces, that treatment (including support, and stopping any medication that might have triggered it) will not wait on lab testing. Biopsy may be used for confirmation. ...Read more

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What're the symptoms and causes of stevens-johnson syndrome?

What're the symptoms and causes of stevens-johnson syndrome?

Severe rash from med: Severe skin rash often from drug allergy, esp sulfa drugs, but also can be from connective tissue diseases. ...Read more

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What is stevens johnson syndrome pictures would help?

Stevens-Johnson: Stevens-johnson syndrome is a rare, serious disorder in which your skin and mucous membranes react severely to a medication or infection. Often, stevens-johnson syndrome begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters, eventually causing the top layer of your skin to die and shed. ...Read more

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Can prilosec cause stevens-johnson syndrome?

Can prilosec cause stevens-johnson syndrome?

Probably: Nearly any drug can cause Stevens Johnson although the mechanism remains unclear. However certain drugs (sulfa for example) are more likely to cause it than others. I suspect that the probability of Prilosec causing it is low but not impossible. ...Read more

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Is there a test for stevens-johnson syndrome?

No: Stevens-johnson syndrome or erytema muliforme is a dermatological reaction, usually allergic to something. ...Read more

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Is there a treatment for stevens johnson syndrome?

Controversial: The only known treatment for sjs is to avoid the offending agent (usually a medicine). Other treatments are controversial and include steroids and ivig. ...Read more

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What is the treatment for stevens-johnson syndrome?

What is the treatment for stevens-johnson syndrome?

Intravenous fluids: Treatment is similar to the treatment of severe burns. Intravenous fluids, stopping any a causative drugs, symptomatic relief of pain, and treatment of any causative infections. Immune gamma globulin therapy is reported to help but the use of cortisone is controversial. ...Read more

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Is it safe to kiss someone with stevens-johnson syndrome?

Is it safe to kiss someone with stevens-johnson syndrome?

Yes: It is not contagious but sjs tends to affect the lips and mucus membranes so it might be painful to the patient with sjs. ...Read more

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Is stevens-johnson syndrome be a side effect of ibuprophen?

Maybe: There apparently have been cases of sjs in people taking ibuprofen. It is very rare if it does occur. ...Read more

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Which treatment works the best and fastest for stevens johnson syndrome?

Get to a burn center: 1. Stop the offending agent 2. Resuscitate and supportive mgmt 3. Infection control - restrict visitors 4. Transfer immediately to a burn center for further management. ...Read more

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What are the treatment options for stevens- johnson syndrome in a child?

What are the treatment options for stevens- johnson syndrome in a child?

Stop medications: Stop medications, as often causative, intensive care treatment, protection from infectious agents. Then, very specialized care and workup for underlying causes. ...Read more

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Is there some connection between stevens-johnson syndrome and celiac disease?

None reported yet: There is an association between hla b 75 and b 15 genes is asian ethnic groups and steven-johnson syndrome but the celiac disease is associated with th hla d genotypes and I am unaware of any studies associating these celiac assoicated genotypes with stevens johnson syndrome. ...Read more

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What kind of pills or treatment can somebody get for stevens johnson syndrome?

What kind of pills or treatment can somebody get for stevens johnson syndrome?

Stevens Johnson synd: Erythema multiforme is a type of hypsersensitivity reaction that occurs in response to medications, infections, or illness. Medications include: barbiturates, penicillins, phenytoin, sulfonamides. Infections include: herpes simplex, mycoplasma. Treatment of severe symptoms may include: antibiotics to control any skin infections; corticosteroids to control inflammation; sometimes IV immunoglobulin. ...Read more

Lamictal (Definition)

Lamictal (lamotrigine) is an anti-epileptic medication, also called an anticonvulsant. Lamictal is used either alone or in combination with other medications to treat epileptic seizures ...Read more


Dr. Jeffrey Cohen
427 doctors shared insights

Lamotrigine (Definition)

Lamotrigine is employed to treat psychiatric problems, and epilepsy. It is one of many meds that can help multiple ...Read more