Top
10
Doctor insights on: Steven Johnson Syndrome Toxic Epidermal Necrolysis

Share
1

1
Please tell me about the stevens-johnson syndrome and toxic epidermal necrolysis?

Please tell me about the stevens-johnson syndrome and toxic epidermal necrolysis?

Hypersensitivity : Stevens-johnson syndrome & toxic epidermal necrolysis are thought to represent the same disease at different levels of severity. Both are immune mediated hypersensitivity reaction to drugs, infection, malignancy or unknown causes (idiopathic). The illness involves the skin & the mucous membranes. Significant & life threatening systemic involvement can occur in the course of the illness. ...Read more

Dr. Emily Altman
99 doctors shared insights

Stevens Johnson Syndrome (Definition)

Sjs is a severe type of allergic reaction to certain medications. The skin and mucus membranes such as the mouth can be effected. This is a life threatening condition that is treated in the hospital sometimes requiring care in a burn unit. Sjs is a complex condition and requires the care of several specialists such as a dermatologist, internist, and sometimes a surgeon ...Read more


3

3
What are toxic epidermal necrolosys/steven johnson syndrome/erythema multiforme"?

What are toxic epidermal necrolosys/steven johnson syndrome/erythema multiforme"?

Serious Problem: Ten (toxic epidermal necrolysis) and (sjs) steven johnson syndrome are the same illness and only are separated by the percentage of body surface area involved. Erythema multiform is usually a much more limited problem. Ten/sjs can be caused by many things, and results in sloughing off of the skin in large areas and can cause severe infection, fluid loss and death. ...Read more

4

4
How are johnson syndrome and toxic epidermal necrolysis related?

How are johnson syndrome and toxic epidermal necrolysis related?

Similar: They are similar but stevens johnson syndrome affects mucous membranes on eyes and mouth. Both are usually caused by reaction to medication but cancer and infections can be triggers also. ...Read more

5

5
Anyone know much about toxic epidermal necrolysis?

Anyone know much about toxic epidermal necrolysis?

Hypersensitivity : Stevens-johnson syndrome & toxic epidermal necrolysis are thought to represent the same disease at different levels of severity. Both are immune mediated hypersensitivity reaction to drugs, infection, malignancy or unknown causes (idiopathic). The illness involves the skin & the mucous membranes. Significant & life threatening systemic involvement can occur in the course of the illness. ...Read more

6

6
My grand daughter was given a toxic dose of zinc , had a severe reaction, skin peeling off entire body, is that toxic epidermal necrolysis?

My grand daughter was given a toxic dose of zinc , had a severe reaction, skin peeling off entire body, is that toxic epidermal necrolysis?

Ask the DR: Zinc toxicity causes diarrhea. There may be vomiting as well. Something very different is happening.You left out too much to get anything else. WHY WAS THIS CHILD GIVEN ANY ZINC AT ALL? What dose? How administered? Once? Or more? There are very few legitimate reasons to take zinc. ...Read more

8

8
Is it possible to get stevens johnson syndrome twice?

Is it possible to get stevens johnson syndrome twice?

Yes, unfortunately: Patients with stevens johnson syndrome can recover and later, even years later, get it again. If the first sjs episode was caused by a known medication, the patient must avoid that medication and similar, related drugs. Some patients may have a genetic pre-disposition (inborn likelihood) to get sjs, which increases their chances of getting it a second time. ...Read more

See 1 more doctor answer
10

10
What's the death rate of stevens johnson syndrome here in the u.S.?

What's the death rate of stevens johnson syndrome here in the u.S.?

Depends on BSA: The death rate from steven's johnson syndrome (sjs) is dependent on the extent of skin sloughing. When body surface area (bsa) sloughing is less than 10%, the mortality rate is approximately 1-5%. However, with more extensive  sloughing (30% bsa)  the death rate is 25-35%, or higher. ...Read more