Doctor insights on:
Are there any promising drugs out there to reverse steroid myopathy? Or is the treatment just exercise
I take seritide and flixotide for copd, and am developing steroid myopathy. What can I do to stop this happening?
If u took a muscle biopsy of someone w/ steroid myopathy what would you expect to see as opposed to a normal person?
Too much steroids: It comes from too many steroids given for asthma , inflammation from different entities that results in more proximal muscle weakness and you have to stop taking them to get better also take in protein and exercise unless it results from a tumor that secretes steroid type compounds it is thought to arise from decrease in muscle protein metabolism causing atrophy. ...Read more
Very likely: Steroid induced myopathy typically gets better when the steroids are discontinued. A lot depends on the type of steroids and the duration of the steroids. Also, you need to balance the myopathy with the rationale for the steroids. There are some situations (ie. Brain tumors) when they are essential for the treatment and management of a different disorder. In general, we try to limit steroid use. ...Read more
I have myopathy due to my use of topical steroids for dermatitis. Now i got tired from long standing or short distant walking.What shall I do to cure?
Exercise!: Incrementally increase your effort as you endurance improves. Any sporting activity, inlcuding walking is good. But get a heart rate monitor and subtract your age in years from 220 and then multiply this times 0.7. This heart rate will be reached with appreciably little speed, if you are deconditioned. As your endurance improves you will be able to walk faster and farther to achieve that hr. ! ...Read more
Do you have one?: Well, if you're a heavy alcoholic, that can GIVE you an alcoholic myopathy among other things; so that's 1 more reason not to be a boozer. In the case of inflammatory myopathies, a high-protein diet MAY be beneficial. Otherwise, there is no special diet for "myopathys." You've made the mistake of lumping all "myopathys" together. There are many different causes and hence different treatments. ...Read more
Disease of muscle: By definition, this is a problem primarily associated with muscular damage and weakness. Classically, many of the disorders are hereditary, e.g., muscular dystrophy, but others may be autoimmune, such as polymyositis. The term implies focal involvement of muscle, as contrasted with neuropathy, which points to nerve problems. ...Read more
Depends on cause: Typically muscle disease can be treated and controlled, but many forms are hereditary and resist current therapies. Some of the inflammatory and mitochondrial forms can be also challenging. This is a rather difficult area, which is being researched continuously. A good online source is the US Muscular Dystrophy Assoc (MDA). ...Read more
Many: Ck with isoenzymes, electrolytes, magnesium, calcium, serum myoglobins, serum creatinine, urinalysis, complete blood count, erythrocyte sedimentation test, thyroid function tests, ast, electrocardiograph, genetic testing, antinuclear antibodies, electromyogram, mri, muscle biopsy. As you can see there are many tests, but the most important thing is to select a physician that is a specialist. ...Read more
Very rare: Myotubular myopathy must be diagnosed by muscle biopsy with special stains to look at the myotubules. It is a form of congenital myopathy but can be rather serious in some cases. Others are quite mild. Usually not progressive, but can cause diffuse weakness and intolerance to exercise. Usually does not affect heart or lung function. But it can affect ability to swallow easily. ...Read more
Significant disease: Hypertrophic cardiomyopathy is a condition in which the heart muscle becomes thick, and obstruction to outflow may occur. Arrhythmias may occur as well. It is commonly inherited, first degree relatives should be screened. Patients may have severe symptoms, or no symptoms at all. It is a common cause of death in young athletes who seemed completely healthy. ...Read moreSee 2 more doctor answers
Different: Muscular dystrophy is usually an inherited form of muscle dysfunction with profound loss of the ability of the muscle to function over time. Treatment current for dystrophy is not satisfactory. Myopathy is any toxic or allergic loss of muscle function and usually responds to treatment. These are usually handled by neurologists but there are specialists in muscles only. ...Read more
Many symptoms: The mm are a group of disorders due to dysfunction of the mitochondria, which are the energy producing parts of the cell. Nerve and muscle cells need a great deal of energy and so are most affected. Symptoms depend on which enzymes / proteins are dysfunctional, but muscle, brain, heart and eye function can be affected. See: http://www.Ninds.Nih.Gov/disorders/mitochondrial_myopathy for more info. ...Read more
Mitochondrial myo-: pathies are a group of neuromuscular disorders inherited from one's mother. Find out the type & which organs it affects, then obtain information & support from mda.org. Mitochondria are cellular power plants that convert fuel from food into energy molecules, particularly important in nerve & muscle cells. See more on genetics at mda.org/disease/mitochondrial-myopathies/causes-inheritance ...Read more