Top
20
Doctor insights on: Stem Cell Transplantation Stem Cells

Share
1

1
Pros and cons of a stem cell transplant?

Pros and cons of a stem cell transplant?

Cure vs toxicity: This depends on the type of transplant (autologous-your own cells; allogeneic-donor cells), the disease that is being treated and the status of the disease. Stem cell transplants do have a higher toxicity than most standard treatments but in many cases can control the underlying cancer for a longer period of time and can cure many cancers that cannot be cured with standard therapy. ...Read more

See 1 more doctor answer
Dr. Keith Stockerl-Goldstein
954 doctors shared insights

Stem Cell Transplantation (Definition)

A stem cell transplant may be needed if you have a disease that damages the cells in the bone marrow or if your received high doses of chemotherapy or radiation. Depending on the type of transplant, your procedure may be called a bone marrow transplant, a cord blood transplant, or a peripheral blood stem cell transplant. All three use stem cells, which are immature cells that give rise to specific cell types. Stem cell transplants are similar to blood transfusions and generally ...Read more


2

2
When is a stem cell transplant used nowadays?

Several diseases: Including acute leukemia, multiple myeloma, some forms of resistant lymphoma, aplastic anemia and a few other rare disorders. ...Read more

3

3
How do I get ready for a stem cell transplant?

How do I get ready for a stem cell transplant?

Information: The best way to prepare is to understand the procedure and potential risks and side effects. Usually your transplant center will have information booklets or videos that explain the procedure. There is a free downloadable resource from nbmt link at: http://www.Nbmtlink.Org/resources_support/rg/index.Htm. ...Read more

4

4
What is stem cell transplantation used for now?

What is stem cell transplantation used for now?

Certain cancers: Blood stem cell or bone marrow transplantation is used to treat certain hematologic malignancies (blood cancers) such as leukemia. They can also be used for bone marrow failure, certain hemoblglobin disorders such as sickle cell anemia, and some genetic disorders. ...Read more

See 1 more doctor answer
5

5
What kind of stem cell transplant is the most common?

What kind of stem cell transplant is the most common?

Blood stem cells: Stem cell transplants using blood stem cells for conditions such as leukemias and other cancers are the most common stem cell transplants. These transplants use stem cells from the blood or bone marrow. ...Read more

See 1 more doctor answer
6

6
What is stem cell transplantation's status in the u.S. Now?

What is stem cell transplantation's status in the u.S. Now?

Used non-manipulated: Use of adult mesenchymal stem-stromal cells (mscs) are currently in clinical trial in us/internationally. Trend is toward use of fat derived mscs, havested by liposuction, isolated and concentrated in tissue culture. Early reports suggest significant improvement in neurological, autoimmune and organ functions. Many more mscs in fat than bone marrow making ad-msc the center of most research now. ...Read more

7

7
How long are you out of commission after a stem cell transplant?

It depends.: The recovery from autologous transplant is much quicker than allogeneic transplant, typically 90 days or so. Recovery from allogeneic stem cell transplant is more difficult to predict, as there are more potential complications, a much slower recovery of immune function that requires avoiding crowds and infection risk for a much longer time. Age and pre-transplant status also play a role. ...Read more

8

8
What are some differences between a sibling stem cell transplant?

Unclear question: I don't understand what you are asking. Differences between a sibling stem cell transplant and what? Please ask the question again with more details. ...Read more

9

9
Are there stem cell transplantation therapy trials in the u.S.?

Are there stem cell transplantation therapy trials in the u.S.?

Yes: Use of adult mesenchymal stem-stromal cells (mscs) are currently in clinical trial in us/internationally. Trend is toward use of fat derived mscs, havested by liposuction, isolated and concentrated in tissue culture. Early reports suggest significant improvement in neurological, autoimmune and organ functions. Many more mscs in fat than bone marrow making ad-msc the center of most research now. ...Read more

10

10
Stem cell transplant in latin america possible?

Hospital Angeles: A wide variety of studies utilizing stem cells are being conducted at hospital angeles in tijuana, mexico. I believe this is also the only jhaco approved hospital in mexico. ...Read more

11

11
What's involved in allogeneic stem cell transplantation?

What's involved in allogeneic stem cell transplantation?

Donor matching.: This involves two people: the (healthy) donor and the (patient) recipient. Donors must have a tissue (hla) type that matches the recipient. Matching is performed on three or more loci of the hla gene, and a perfect match at these loci is preferred. Even with this, immunosuppression is often needed due to graft vs host disease. ...Read more

See 1 more doctor answer
12

12
Why is a stem cell transplant dangerous for the elderly?

Why is a stem cell transplant dangerous for the elderly?

Stem cell transplant: Stem cell transplants are very demanding on the body and multiple organ systems. The person undergoing transplant is immunosuppressed and high-risk of infections. The medications and process increase the risk for complications in other organ systems, risking their failure. While improvements are being made, most studies on outcomes in the past looked at people in their 6th decade or earlier. ...Read more

13

13
For leukemia has anyone had a successful stem cell transplant?

For leukemia has anyone had a successful stem cell transplant?

Many: There are different types of leukemia, lymphoid vs myeloid, acute vs chronic. Some leukemia can be treated for chemotherapy only, some leukemia will need to be treated by stem cell transplant. The outcome of stem cell transplant is different depending on what type of leukemia a patient has. However, stem cell transplant has an established record to cure leukemia. ...Read more

14

14
Is there a centre for autologous stem cell transplantation in mumbai?

Probably: Asia is amongst the leaders in development of adult stem cell centers and applications. ...Read more

15

15
What is an autologous stem cell transplant and am I a candidate for one?

What is an autologous stem cell transplant and am I a candidate for one?

Means of treatment: In some cases, the best way to treat the disease, especially if it has come back after initial treatment is to use doses of chemotherapy or radiation which is high enough to destroy normal bone marrow cells. To "rescue" these cells, they are stimulated with drugs before high dose therapy that cause very immature cells called stem cells to enter the blood where they can be collected and given back. ...Read more

See 1 more doctor answer
16

16
Refractory ALL in adolescent male 21 years management other than Allogeneic Stem Cell Transplant?

Refractory ALL in adolescent male 21 years management other than Allogeneic Stem Cell Transplant?

Complex question: only experts in the field, hematologists/oncologists would answer this question after careful review of the case and different options available, I know it might be frustrating at times, but complex condition as ALL need to be managed in specialized hospitals/institutions, it's your right as a patient to have second and even third opinion, but in the end you have to trust the treating team, good luck ...Read more

17

17
Has anyone had a successful stem cell transplant for cancer?

For certain diseases: Stem cell transplants (bone marrow transplants) are often successful at treating cancers of the blood and bone marrow such as leukemias, lymphomas and multiple myeloma. They can also be used to treat some disorders of the red blood cells and immune system. ...Read more

18

18
Can stem cell transplantation be used to treat solid tumors yet?

Can stem cell transplantation be used to treat solid tumors yet?

Not likely.: It is most often done for patients with certain cancers of the blood or bone marrow, like multiple myeloma or leukemia. Graft-versus-host disease is a major complication. Others include veno-occlusive disease, mucositis, infections (sepsis), and oral cancer, so it is unlikely to be used for new things yet. It is reserved for life threatening conditions. ...Read more

See 1 more doctor answer
19

19
What should I do to disinfect/sterilize my home prior to stem cell transplant?

Nothing;: Don't get stem cell transplants! they are unproven and potentially risky, especially when used in breasts. Some cells die and cause scar tissue and calcification that can mimic cancer on mammogran, or interfere with the detection of cancer. Most "stem cell" transplants are hype and marketing right now, though some legitimate research is going on. Check the academic credentials of "surgeon!". ...Read more

20

20
Why are 2 umbilical cords sometimes used in an allogeneic stem cell transplant?

Increased stem cells: The rate of engraftment in adults following an umbilical cord blood stem cell transplant (UCBT) is quite slow. This increases risk of infection while the WBC count is low, and requires a longer period of RBC and platelet transfusion support. To speed up the rate of engraftment double UCBT are often used. Early both cord units might produce WBC, but later a single unit predominates. ...Read more

See 1 more doctor answer
Dr. Michael Kleerekoper
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


Dr. Suzanne Galli
1 doctor shared a insight

Stem Cell (Definition)

The capacity to "grow up" or differentiate to produce mature cellular elements. In blood production rbc, WBC and platelets. Fundamentally, stem cells can also self-replicate and thus provide a pool of ...Read more