Doctor insights on:
Stem Cell Retina
Embryonic stem cell: Embryonic stem cell research has not shown to be as effective as adult stem cells and induced pluripotent cells. in 2009, NIH called embryonic stem cells “obsolete" as can use adult stem cells with better results. See [email protected] for more info. ...Read moreSee 2 more doctor answers
Origin: Embryonic stem cells are derived from fertilized eggs created to help couples who have difficulty conceiving. This is "murder" according to some religionists. Other stem cells come from other sources. However, since the striking success of embryonic stem cells in early studies on wet macular degeneration, even the conservative presidential candidate no longer seems opposed to their use. ...Read moreSee 1 more doctor answer
Donor matching.: This involves two people: the (healthy) donor and the (patient) recipient. Donors must have a tissue (hla) type that matches the recipient. Matching is performed on three or more loci of the hla gene, and a perfect match at these loci is preferred. Even with this, immunosuppression is often needed due to graft vs host disease. ...Read moreSee 1 more doctor answer
Stem cells: Adult stem cells have helped Leukemia, lymphoma. We have been using limbal stem cell transplants in eye surgery for years with excellent results. See [email protected] Stem cell injections are now being used to treat painful joints (shoulders, hips, etc) Still there are few published studies proving its benefit in some of these conditions. No published study saying cures optic atrophy yet ...Read moreSee 1 more doctor answer
Stem cells safety: Stem cell safety depends on what kind and where it is being used. Embryonic stem cells have been found to be too costly and risky for causing cancers compared to adult stem cells. Bone marrow Stem cell transplants have been used for years for cancers and is safe. see Eyedoc2020.blogspot.com for more info and safety info. ...Read moreSee 2 more doctor answers
Limited to Date: For surgical replacement of diseased arteries, taking cells from an intended recipient to grow in lab over months to populate a scaffold structure (e.g. Pig artery with cells washed away using detergents) is being done; limited, slow & does nothing about intrinsic disease. For the original disease, best is to optimize the ds drivers within each of us: lipoproteins, blood sugar, bp, no smoking etc. ...Read more
Perhaps our future.: A human embryo consists of 50-150 embryonic stem cells 4–5 days after fertilization, and those few cells eventually differentiate into all of the different specialized cells that compose the entire human body. Since those stem cells can potentially be anything they want to be, the potential for curing multitudes of human disease, using them, is enormous. ...Read moreSee 1 more doctor answer
Definition stem cell: All humans first start as a fertilized ovum, which is totipotent ("potential to become every cell"). After several days, it grows into an embryo, comprised of embryonic stem cells. Embryonic stem cells are still very unspecialized, and are described as being pluripotent ("potential to become a wide variety of cells"). Adult stem cells are multipotent ("a limited potential for differentiation"}. ...Read moreSee 4 more doctor answers
Yes, but!: Many types of stem cells have been made to form cartilage (including stem cells from fat, marrow, amnion, blood). I have even personally done much research on this. However, the problem is that we have no good way of placing the cartilage back into the knee (or other joint) and keep it in place while the body heals. There are encouraging trials, but no definitive solutions yet. ...Read moreSee 1 more doctor answer
Can embryonic stem cell be preserved the same way as cord blood stem cell? Possible to retrieve single stem cell clinically in IVF w/o harming embryo?
No: Technology not currently developed to support this strategy. ...Read more
Remission: Multiple myeloma is treated classically with chemotherapy and autologous stem cell transplantation. Both modalities can put the disease on remission and prolong life substantially. I personally do not offer allogeneic stem cell transplant for multiple myeloma unless on clinical trial or under very stringent circumstances. Multiple myeloma remains an incurable but very treatable disease. ...Read moreSee 2 more doctor answers
Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?
One of the other: Stem cells can be obtained from 3 different sources: from Bone marrow of the Donor, blood of the donor or stem cells from umbilical cord. But we have to give an adequate number(Dose) of stem cells in order to have full protection. So combining them may only be needed because of inadequate number of stem cells from one of the sources ...Read more