Doctor insights on:
State Afp Program Handling
Liver and testicular: An alpha-fetoprotein (AFP) is a blood test that checks the level of AFP in a pregnant woman's blood. It is a substance made in the liver of the fetus. The level of AFP in the blood of a pregnant woman can help see whether the baby may have chromosomal abnormalities . The test is also used as a tumor marker to help detect and diagnose cancers of the liver, testes, and ovaries. The AFP is often ordered to monitor people with chronic liver diseases because of an increased risk of developing liver cancer. ...Read more
Screening test: An abnormal AFP simply means that your test results showed your risk of an abnormality was higher than your risk from your age alone. This is a screening test meaning that the vast majority of people will be normal and a small group will fail the test and require more testing. The next set of tests are what is important to determine if anything is wrong. ...Read more
Negative: AFP is the screening test for neural tube defects and down's syndrome .Normal test means your risk of having a baby with down's is very low compared to what the riskis at your age. ...Read more
Could there be a correlation that would explain elevated ptt, high ALDO/PRA RATIO, low pregnenolone and elevated AFP?
AFP: Afp, or Alpha fetoprotein, is a fetal protein that is used to screen for the presence of neural tube defects. Higher levels of AFP are seen in mother's blood and amniotic fluid when a baby has an open neural tube defect. The test is done in the second trimester of pregnancy. AFP is also used as a tumor marker for some hepatic cancers. Following AFP levels could alert doctors to tumor recurrence. ...Read more
Clinical context: AFP blood tests can be used for a variety of things. In pregnancy it is used as part of genetic and neural tube defect screening. It can be used to detect liver disease and germ cell tumors of the ovaries and testes. Results should be evaluated in the clinical context. Patients without a problem should have very low AFP levels. ...Read more
AFP: Alpha-fetoprotein (AFP) test is a blood test performed during pregnancy.This screening test measures the level of AFP in the mother's blood and indicates the probability that the fetus has one of several serious birth defects.Afp is elevated when there are neural tube defects eg spina bifida. ...Read more
Elevated: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, our AFP level is elevated and you should discuss it with your doctor. See this site for more information. http://www.nlm.nih.gov/medlineplus/ency/article/003573.htm ...Read more
Prediction?: Predictive value for what? A high AFP is associated with a fetus with a neural tube defect. A large nuchal translucency is associated with chromosomal abnormalities and cardiac defects. A normal level ii ultrasound reduces the risk of structural abnormalities in the fetus. So it depends upon what you are testing for. ...Read moreSee 1 more doctor answer
I'm very nervous to take the AFP prenatal test tomorrow. Why does it have such a high false positive rate?
Gestational Age: It is an indirect test, in other words it does not test the baby directly like an amniocentesis. Other factors unrelated to the health of the baby can affect it but the most common is that your due date was off by a few days and when that is corrected in the calculation made by the lab its usually fine. ...Read more
I have had four alphafetoprotein tests: 16.2, 17.4, 19.0, 19.5 can you have elevated AFP and be disease free?
Is your AFP level : Elevated?. What is the normal range for the lab doing your test? Why were you tested? AFP may be elevated in a woman carrying a child with spina bifida, or in person with liver disease and or liver tumors, and in some genital tumors. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003573.htm. ...Read more
Not very.: The triple screen will detect about 70% of mothers carrying babies with down syndrome, but it is only a screening test and does not diagnose down syndrome. There are many false positive tests ("abnormal" tests in women who are carrying babies that do not have down syndrome). A newer blood test for fetal dna in the mother's blood can actually diagnose down syndrome in women who are at higher risk. ...Read moreSee 1 more doctor answer
What do you suggest if my female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . .?
Pregnant or not?: Alpha-fetoprotein (AFP) is used during pregnancy as part of the "Quad Screen". This is a test that includes AFP and three other blood chemicals to screen for Trisomy 18, Trisomy 21 and Neural Tube defects. If the quad screen is abnormal, a referral to see a perinatologist for a detailed ultrasound and additional testing is in order. AFP can also be tested as part of a cancer work-up. ...Read more