Top
30
Doctor insights on: Stages Of Primary Biliary Cirrhosis

Share
1

1
Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. Http://www. Medicalnewstoday. Com/releases/151640.php. ...Read more

Dr. Daniel Saurborn
1 Doctor shared a insight

Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


2

2
What exactly is primary biliary cirrhosis?

What exactly is primary biliary cirrhosis?

Liver disease: Primary biliary cirrhosis is an autoimmune liver disease seen most commonly in women in the 4th to 5th decade of life. It generally presents with unexplained itching and occasionally jaundice. It is frequently found on routing screening liver tests which may show an elevated alkaline phosphotase. Though not curable it is treatable and treatment slows the progression to cirrhosis. ...Read more

3

3
How can I treat primary biliary cirrhosis?

How can I treat primary biliary cirrhosis?

Ursodiol: There is not much available to treat primary biliary cirrhosis, but ursodiol helps normalize the liver enzymes. For other therapies you should discuss with a hepatologist. ...Read more

4

4
What is the cause of primary biliary cirrhosis?

Autoimmune: An autoimmune disorder in which the body attacks it's own liver. ...Read more

5

5
What can be done for primary biliary cirrhosis?

Number of things: If caught early, there are medications, particularly ursodeoxycholic acid (actigall) which can slow it down. Preventing and treating complications is also important, especially high pressure in the portal vein, which can be treated with beta blockers (inderal (propranolol) and others) and sometimes surgery. Itching, fatigue and other symptoms can be treated as well, but liver transplant is needed when severe. ...Read more

6

6
Can you tell me about primary biliary cirrhosis?

Liver disease: Chronic disease of the liver from scarring of the biliary ducts. Probably an autoimmune disease. There are medications to help with this disease, but you need close follow up with a GI doc. Good luck. ...Read more

7

7
What can I expect if I have primary biliary cirrhosis?

Maybe liver failure: Primary biliary cirrhosis is an insidious disease that tends to be progressive over time. The small ducts that drain bile from the liver will narrow and prevent adequate drainage of bile to the intestine. The liver will experience damage with years of inadequate bile drainage and eventually severe scarring (cirrhosis) occurs. With cirrhosis, the only option is liver transplantation for best chance. ...Read more

8

8
Has anyone survived primary biliary cirrhosis for long?

Yes: There are some new medications that have been effective for stopping the progression of primary biliary cirrhosis, particularly urso-
deoxycholic acid. In addition, liver transplanation can be lifesaving, and patients can live normal lifespans after liver transplantation, although the need for anti- rejection drugs can affect the quality of life and cause complications which shorten life as well. ...Read more

9

9
How does one effectively treat primary biliary cirrhosis?

How does one effectively treat primary biliary cirrhosis?

Not a great answer: Unfortunately, there is no cure. The autoimmune disorder destroys the liver over time. The treatments help to relieve the symptoms (ursodiol, anti-itching meds, anti-inflammatory meds, immune suppressing meds etc.) and if the disease progresses to final stages, liver transplant is the only really treatment. ...Read more

10

10
Could I get a handicap parking placard for primary biliary cirrhosis?

Why do you ask?: These permits are placed for people who have much more physical difficulty walking than do other peoples. If you have ascites and muscle wasting from primary biliary cirrhosis, this might be fair. If you have mild disease, and people see that you are asking for a special privilege that someone else would need far more, you'll lose the respect of your peers. Make the best choice. ...Read more

11

11
What number of years can someone live with primary biliary cirrhosis?

Many years: Primary biliary cirrhosis (PBC) is usually diagnosed with lab tests and liver biopsy. People can live many years with PBC. Without knowing more information, I can't give you exact numbers, but hopefully you are on ursodiol medication and this helps PBC a lot. You should be following with a liver doctor who will help manage your disease. ...Read more

12

12
What differentiates primary biliary cirrhosis from other types of cirrhosis?

What differentiates primary biliary cirrhosis from other types of cirrhosis?

Location of inflam: Agree with dr. Edmisson. Pbc is autoimmune disease affecting bile ducts; can eventually lead to progressive liver disease and cirrhosis (scarring).
Othe types of cirrhosis usually involve inflammation of the liver cells, due to infection (like hep b, c), toxic chemicals, metabolic disease e.g.Nonalcoholic fatty liver (seen in obesity, diabetes) iron overload, damage from alcohol, autoimmune. ...Read more

13

13
Help please? How many years can someone live with primary biliary cirrhosis?

Many years: Primary biliary cirrhosis (PBC) is usually diagnosed with lab tests and liver biopsy. People can live many years with PBC. Without knowing more information, I can't give you exact numbers, but hopefully you are on ursodiol medication and this helps PBC a lot. You should be following with a liver doctor who will help manage your disease. ...Read more

14

14
What is the definition or description of: primary biliary cirrhosis diagnostic panel, comprehensive?

PBC: Primary biliary cirrhosis is an autoimmune disease of the liver marked by the slow progressive destruction of the small bile ducts within the liver. When these ducts are damaged, bile builds up in the liver and over time damages the tissue. This can lead to scarring, fibrosis and cirrhosis. ...Read more

15

15
My friend as just been told she as primary biliary cirrhosis and it at the advance stage can she still live for many years?

See below: A liver transplant would be her best chance of long life. However there is a drug that a patient with this can take and it depends actually on how advacned her disease is-so her doctor should be able to help answer that. ...Read more

16

16
What is primary biliary cirrhosis (liver) like?

What is primary biliary cirrhosis (liver) like?

It's variable.: Depends on how long you have had it. Usually without symptoms early in the disesae. May be associated with itching, hypythyroidism, fatigue, osteoporosis and dry eyes. Can progress to cirrhosis over time. If you have pbc, you should talk with your doctor about what stage your disease is. ...Read more

17

17
What are early signs & symptoms of primary biliary cirrhosis?

None: Early on primary biliary cirrhosis can be associated with little or no symptoms at all, just like many chronic liver diseases. As the disease progresses, however, many people start experiencing chronic fatigue & weakness, jaundice and itching (from bilirubin build up in skin), followed by complications of cirrhosis such as ascites & malnutrition. ...Read more

18

18
Why do the sufferers of primary biliary-cirrhosis feel so tired all the time?

PBC = inflammation: Primary biliary cirrhosis is an autoimmune inflammatory disease, manifest by low but persistent liver damage. This causes a variety of biochemical changes which manifest by fatigue. Not all patients have fatigue, many patients are asymptomatic until the disease is advanced. Cirrhosis is also associated with fatigue. ...Read more

20

20
How common are kayser fliescher rings in cholestasis and primary biliary cirrhosis, I have them, is it just as likely those two things as Wilson's?

Whoa: You cannot self-diagnose Kayser-Fleischer rings. Several percent of young folks have arcus lipoides, and there are other things that mimic it. They're specific for Wilson's and usually show up late, the person being quite sick already. If you think you may have cholestasis, primary biliary cirrhosis, and/or Wilson's, get with a competent gastroenterologist -- the workups are tricky. ...Read more

21

21
I need information on primary biliary cirrhosis I am a 69 year female was diagnosed in 2010. What is the best test to confirm the disease. And where would be the best place for a second opinion? What should I look for as signs of progessing in the dise

Liver biopsy: Is the gold standard, and a diagnosis cannot really be made without it, although blood tests, scans and medical history/family history can strongly suggest it. Most major medical centers. Like emory university hospitals in atlanta, have liver specialists who further sub-specialize in primary biliary cirrhosis. Increasing fatigue is most common symptom of progression, with jaundice and itching. ...Read more

22

22
Primary biliary cirrhosis:best treatment options, what to do?

Primary biliary cirrhosis:best treatment options, what to do?

Liver trasplant: See a liver specialist will manage initially medical treatment, and enroll you in the program ...Read more

23

23
If you are diagnosed with primary biliary cirrhosis, what are best treatment options?

Liver transplant: There are treatments that would reduce the symptoms in early stage of the disease. In the advanced phase, liver transplant would be the best option. See this site for more info.
http://www. Mayoclinic. Com/health/primary-biliary-cirrhosis/ds00604. ...Read more

24

24
Primary biliary cirrhosis - early stages. Can I have a gastric band for weight reduction?

Rethink: Would carefully discuss this with your gastroenterologist and with the surgeon who is contemplating this procedure. Without fully evaluating you impossible to say for certain, but this sounds like a very risky option under the circumstances. Good luck. ...Read more

25

25
Is there anything you can use over-the-counter for itching due to primary biliary cirrhosis?

Is there anything you can use over-the-counter for itching due to primary biliary cirrhosis?

Possibly: Bathing in colloidal oatmeal (much more finely ground than what you eat for breakfast) and using skin moisturizers may help. Cold packs placed over the skin may soothe the itching. If okay with your doctor & your other medicines, you might consider using milk thistle -- check with doctor first. Some antihistamines are available otc, but may also make you drowsy. Don't smoke. ...Read more

26

26
Please tell me what can cause sudden elevation of liver levels in a primary biliary cirrhosis pt on meds?

Repeat and see GI: Primary biliary cirrhosis is an autoimmune disease of the liver that affect women more than men. Medications for treatment include ursodeoxycholic acid and steroids for acute flairs. Transient elevations may occur for a variety of reasons: 1) exacerbation of pbc; 2) injury to liver from another cause, e.g. Alcohol, tylenol; 3) viral infection, hepatitis or other virus. Repeat labs and see md. ...Read more

27

27
Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Immune dysregulation: The immune system is not functioning normally in primary biliary cirrhosis. That and the chronic inflammation contrive to raise IgM. ...Read more

29

29
What's the difference between primary biliary cirrhosis and primary sclerosing cholangitis?

Similar symptoms: Distinct diseases that announce themselves in the same way. Both destroy the small bile ducts within the liver and produce jaundice, itching and sometimes failure of the liver. The microscopic picture, labs, and treatment options are as strikingly different as the presentations are similar. ...Read more

30

30
Elevated alkaline phosphatase value of 125 U/L. Is this a sign of primary biliary cirrhosis? Could the level be due to my Hep B?

High level,,,: This is a high level for alkaline phosphatase certainly, but to say it's from primary biliary cirrhosis is harder as there are other things like high bilirubin and symptoms like itching and jaundice (yellow skin) and antibodies like anti-mitochondrial antibodies. It also could be due to Hep B or any increased liver activity or other things and it's not that high so see your Dr. For other tests. ...Read more

Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


Dr. Thomas Fiala
64 Doctors shared insights

Primary Biliary Cirrhosis (Definition)

A condition where the bile ducts of the liver break down. This causes a buildup of bile in the liver, including ...Read more