Doctor insights on:
Stages Of Kidney Failure From Multiple Myeloma
Plasma cell cancer: Multiple myeloma is a cancer of plasma cells (pcs). Pcs are the specialized b lymphocytes that produce antibodies. When there is a cancer or one (mono-) clone (= monoclonal, m) pc population they can product m-proteins. Symptoms include crab - hypercalcemia, renal (kidney) insufficiency, anemia, bone disease; also infection and pain. More: http://www.Cancer.Net/cancer-types/multiple-myeloma. ...Read more
Kahler disease is also known as Multiple myeloma. I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
My brother (51) is in the final stages of multiple myeloma and was told he will die of kidney failure. Blood tranfusions weekly. Timeline estimate?
Get extra support: Agree with prior answer that difficult to say. If not already involved ask for a palliative medicine specialist to work with your hematology-oncology team. They might be able to provide additional prognostication opinions as they monitor his progress and also provide additional support for the time that he has. ...Read moreSee 1 more doctor answer
Kidney biopsy shows the reason for kidney failure is multiple myeloma. No bone damage, hemo. More than 12. Will kimo therapy help to recover fully?
Seek opinion from a: This is unusual way to make a diagnosis of multiple myeloma(mm). Typically we need to do a bone marrow biopsy and look for cancer cells in the marrow. These cells produce abnormal proteins(m protein) which will show up either in the blood(commonly) or in the urine. We use a test called protein electrophoresis. If these tests have not been done, seek a second opinion. Chemo will help to control mm. ...Read more
Depends: This can best be answered by your treating physician. It often depends on age, other medical disorders, previous treatments, response to velcade. Most patients will have improvement in renal failure if this is the first treatment they receive, and the treatment usually includes velcade. ...Read more
Why sickle cell anemeia / multiple myeloma cause diabetes insipidus ? Is it because it may obstruct the blood flow to the kidneys and damage them?
Basically right: Even sickle cell trait ruins much of the concentrating ability of the kidneys by adulthood. Myeloma is more likely to damage and obstruct the tubules themselves. Both produce a kidney lesion that prevents the urine from becoming concentrated, rather than a pituitary diabetes insipidus. ...Read more
Quite a bit: Of variability , but on average 5-7 years. ...Read more
See below: Treatment for multiple myeloma has improved markedly and drug treatment alone or drug treatment with auto or donor stem cell transplants can produce decades long remissions. See this site for more info. http://www.mayoclinic.org/diseases-conditions/multiple-myeloma/basics/definition/con-20026607 ...Read more
My 80 yr husband has multiple myeloma. He won't eat. Can walk, but lies in bed or couch all day. Dr. will not discuss 'stage'. I know he is failin?
2nd opinion v hospic: Check out http://www.mayoclinic.org/diseases-conditions/multiple-myeloma/basics/treatment/con-20026607 for info on multiple myeloma and its treatments. Get a 2nd opinion (or change physicians - your Family Doc can help you find Oncologist who accepts your/his insurance). If no treatment is desired, consider hospice for comfort/palliative care. Again, your Family Doc can refer or you can ask on own ...Read moreSee 1 more doctor answer
Multiple myeloma is a cancer of plasma cells (pcs). Pcs are the specialized b lymphocytes that produce antibodies. When there is a cancer or one (mono-) clone (= monoclonal, m) PC population they can product m-proteins. Symptoms include crab - hypercalcemia, renal (kidney) insufficiency, anemia, bone disease; also infection ...Read more
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
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