Doctor insights on:
Stage 4 Non Hodgkin's Lymphoma Life Expectancy
What is life expectancy for stage 4 non-hodgkin's lymphoma that has spread to spine, liver & spleen?
Still good prognosis: Survival rates for nhl vary widely, depending on the lymphoma type, stage, age of the patient, and other variables. The overall 5-year relative survival rate for patients with non-hodgkin’s lymphoma is 63% and the 10-year relative survival rate is 51%. All the best, hk. ...Read more
Many good treatments: You should go and see a Medical oncologist. They can treat you with chemotherapy which works very well and can often cure this disease. But avoid delays in getting to a good Oncologist or to a major Cancer center where you can find specialists for treating Lymphoma. ...Read more
Depends.: Life expectancy after diagnosis is dependent upon stage of disease among other things. The earlier the stage the better the prognosis and the longer we expect someone to remain in remission and the longer we expect them to survive. ...Read more
I had stage 4 aggressive non-hodgkin's lymphoma last year, 6 months later I am cancer free! What are the chances of it coming back?
Better than even: This depends on variables including your age (younger does better), but even ten years ago, about 2/3 of people with stage IV (and stage is the major prognosticator) who were alive at one year were alive at ten (at which point it's unlikely to recur). Your oncologist has better numbers, but for any individual, it's either 0% or 100%. Cherish each new day, and best wishes. ...Read more
Depends on subtype: There are many different subtypes of non hodgkin lymphoma. Some are highly curable despite their advanced stage (stage iv), such as diffuse large b cell lymphoma. Others are very slowly growing and patients can survive for yrs or even decades, such as follicular or small lymphocytic. ...Read more
It can be cured: And you are likely on retuximab too. Please ask your doctor why thaey have not made clear what your chances are, and why you should be optimistic. ...Read more
Use IPI/FLIPI Score: The prognosis of nhl (non-hodgkin lymphoma) is better defined by a score called the international prognostic index (ipi) for aggressive nhl or follicular ipi (flipi) for low grade nhl. Age, performance status, stage, extra nodal sites, ldh value, hemoglobin, Albumin are figured into the score which categorizes pts into low, intermediate or high risk for relapse or poor survival. ...Read more
Diagnosis. B.Cell non hodgkin, s lymphoma favor burkitt, s lymphoma. This us the result of biopsy taken during appendicectomy. D20 positive and tdt neg?
CD20 is a B-Cell: Marker hence the assignment of a b-cell nhl. Tdt is an immunohistochemical stain used to classify blood cells. Burkitt's is a very aggressive process -- get started on a plan with a hematologist straight away. ...Read more
Systemic and local: Non hodgkins lymphoma may cause systemic symptoms such as weight loss, fever, night sweats and itchiness. Locally, it can present as a lump or sweling in the head and neck, groin or any lymph node area. If it's large, it can obstruct passage ways such as esophagus, intestines, ureter or blood vessels. If it involves the chest, it may give symptoms of cough, shortness of breath or pain. ...Read more
A lot: Both hodgkin lymphoma (formerly known as hodgkin's disease) and non-hodgkin lymphoma (also known as non-hodgkin's lymphoma) are lymphomas, a type of cancer that originates in a subset of white blood cells called lymphocytes. Lymphocytes are an important part of your immune system. The main difference between hodgkin and non-hodgkin lymphoma is in the specific lymphocyte each involves. ...Read more
Anyone briefly tell me what lymphoma (non hodgkin's) is and what types of things/viruses can cause it?
In general (generalizing 40+ lymphomas), nhl is very responsive to chemotherapy.
Refractory (non-responsive) nhl is bad.
Not all nhl is curable (eg follicular lymphoma), but even in those cases people often do well with continued treatments and/or maintenance therapy.
There are some very difficult/bad lymphomas such as ptcl and lymphomas can cause bad symptoms at diagnosis such as svc syndrome. ...Read more
Nhl has over 40 subtypes.
Treatment depends on dx, stage, prognosis, tumor & patient factors.
Dlbcl: r-chop most common
fl: observation vs. Rituximab vs. R-chop vs. R-bendamustine vs. Other...
That is vague, but there is no general answer. ...Read more
Many, depends: There are many treatment options for non-hodgkin's lymphoma (nhl). There are 40+ sub-types of nhl. While many have the same treatment, the treatment approach and treatment intent varies by lymphoma. If the nhl is cd20+ then the monoclonal antibody Rituximab can be used alone or in combination with standard (cytotoxic) chemotherapy. Other potential tx include radiation and clinical trials. ...Read more
No: Only indication is for hodkin's disease, and even in that condition, where it is used as part of the "mopp" regimen, it has been replaced by other regimens. It may have slight activity in other lymphomas but there are now many other effective chemotherapeutic and biologic choices. ...Read more
Along with your Dr.: Your oncologist will review your type of non-hodgkin lymphoma and then discuss treatment. A clinical trial may also be offered and this may take some time on your part to review the study that is given to you. Of course, your doctor and his/her staff, including the research team should be available to help you make a decision on a clinical trial. ...Read more
Not really: Non-hodgkin's lymphomas are a very large group of diseases. Lymph cell can be called t cells or b cells based on surface proteins. T cell lymphomas are just one group of non-hodgkins lymphomas. There are also several types of those tcell lymphomas. ...Read more
Depends: Chemotherapy can make you tired as well as your disease. Depending on your overall condition, it may be hard to work full time or at all. The portacath may limit some types of exercise and work duties. It is also good to stay out of crowds to reduce infection. Having said that, I have many patients who have little change in their routine except on the days they receive chemotherapy. ...Read more
My grandmother has indolent Non-Hodgkin's lymphoma. Is this a risk factor for me. Or is it only when a parent has it.?
Low risk: Non Hodgkin's lymphoma, like most cancers, has a slight tendency to run in families. However, it's mostly just random chance that leads to the combination of mutations that cause the disease. Even identical twins are not at very high risk if the other gets it. So I would not worry about a history in grandparents. ...Read more
Spread pattern: Primarily, hodgkins lymphoma teens to spread from one lymph node site to an adjacent site. Non hodgkins lymphoma is more likely to skip lymph node chains to spread distantly. This is why local radiation has historically be more important in the treatment of hodgkins than non hodgkins. ...Read more
Complex question: There are many different types of non-hodgkin's lymphoma and they have many different causes. Some of the lymphomas are caused by viruses and bacteria (some burkitt lymphoma, marginal zone lymphoma of the spleen, acute t-cell lymphoma). Others occur as people age because of the genetic mutations that are continually occurring in the immune system. Lymphomas spread because they are part of the immune system nd immune cells naturally travel around the body. ...Read more
Its cancer of Lymph: Lymphoma is a Cancer arising from the lymph glands. There are several subtypes. Ask your oncologist more about it. Tell us if you or a family member is affected by Lymphoma and what is being done in terms of treatment.?? A majority of lymphomas can be cured when treated with modern treatments. ...Read more
Normal?: I'm not sure what you mean by normal. It is not uncommon in this age group. ...Read more
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