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Doctor insights on: Stage 3 Colon Cancer Adjuvant Therapy

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3 cycles of chemotherapy so far for metastic colon cancer shows therapy working, if 2 cycles are missed due to ill health, will cancer start growing agsin?

3 cycles of chemotherapy so far for metastic colon cancer shows therapy working, if 2 cycles are missed due to ill health, will cancer start growing agsin?

No: If 3 cycles of chemo given and well tolerated, evaluation might show stability or regression if drugs working. If missing 2 cycles, this will not allow further regression while off medication, but if resumed a further response may be defined. Most combo drugs for colon cancer may show a termporary response but not cure. The newer combinations with Immunochemotherapy more effective. ...Read more

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Dr. Barry Rosen
4,310 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How effective is neoadjuvant therapy for treating colon cancer?

How effective is neoadjuvant therapy for treating colon cancer?

Partially: Chemotherapy in all of its forms is only partially helpful in improving the survival of colon cancer. When there is an effective neoadjuvant response the remaining lesion can be successfully resected. Complete surgical extirpation is the needed result. As immunochemo becomes more effective then the combination with surgery will even produce better results. ...Read more

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What is radiation therapy treatment for colon cancer?

What is radiation therapy treatment for colon cancer?

Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read more

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How effective is radiation therapy for treating colon cancer?

How effective is radiation therapy for treating colon cancer?

Partially effective: The best approach for colon cancer is resection. If lesion is large such as one in the rectosigmoid, then RT plus chemo can be employed to reduce the lesion for resection. While the end effect minimizes local recurrence, it does not alter overall survival. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors (Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used (5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Is it possible to get radiation therapy for colon cancer?

Is it possible to get radiation therapy for colon cancer?

Yes: Radiation is standard treatment for rectal cancers which have not spread and is used in combination with chemotherapy. For pure colon cancers, radiation is used sometimes in special situations (e.g. Cancer involving nearby critical organ or causing pain/ bleeding). The main therapies for colon cancer though are surgery and chemotherapy. ...Read more

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Can any targeted therapies or other drugs help with metastic colon cancer when Xeloda (capecitabine) n irinotecan has failed?

Can any targeted therapies or other drugs help with metastic colon cancer when Xeloda (capecitabine) n irinotecan has failed?

Yes: Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin (bevacizumab) or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept. FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available. ...Read more

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Can radiation therapy be delivered to a colon cancer from a device inside a patient?

Can radiation therapy be delivered to a colon cancer from a device inside a patient?

Yes: In some universities and major institutions there are dedicated machines for intraoperative radiation given to an area of concern that the surgeon could not resect and this device is aimed inside the abdomen to give the radiation. This is not common or widely available and outside machines are more readily available. ...Read more

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If I have colon cancer and get radiation therapy, can I safely have sex with my husband?

If I have colon cancer and get radiation therapy, can I safely have sex with my husband?

Yes: Once you leave the radiation room there is no radiation left in you to effect your husband. As long as you do not have discomfort in the abdomen, pelvis or genitals there is no reason you can not have sex. ...Read more

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Can radiation therapy help to treat colon cancer that's spread to the liver or kidneys?

Can radiation therapy help to treat colon cancer that's spread to the liver or kidneys?

Yes: If the disease is limited and original colon cancer addressed focal intense radiation called radiosurgery can be very effective. If there is significant disease then standard radiation can be used to help symptoms. ...Read more

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What is the most effective chemotherapy for stage 3 colon cancer?

What is the most effective chemotherapy for stage 3 colon cancer?

See an oncologist: Colon chance chemotherapy has a lot options now, and a thoughtful short and potential long term plan is what I necessary. Some oncologist believe that one day soon metastatic colon cancer may even be able to be treated as a chronic disease. I have certainly seen patients live for a decade with stage 4 disease. I wish you all the best. ...Read more

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My Dad was diagnosed with Stage 3 colon cancer at age 54. When should I get my first colonoscopy?

At about 44 years: The general rule is to get a colonoscopy about 10 years before the age a relative developed colon cancer. You may wish to monitor occult blood in stool with a FIT test. It would be prudent to discuss these issues with your doctor. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

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What is the life expectancy for a 78 year old man with stage 3 colon cancer which has not spread?

What is the life expectancy for a 78 year old man with stage 3 colon cancer which has not spread?

Variable: There is >50% chance that your colon cancer is cured with surgery already, in which case your life expectancy should be like a normal healthy person. You may benefit from treatment using adjuvant chemotherapy, if your tumor had spread/involved the lymph nodes in the abdomen. Check with your doctor and let us know how many nodes were involved with your tumor? ...Read more

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My husband had a colon tumor removed they got it all but has stage 3 colon cancer 6 of 20 lymph nodes what does this mean?

My husband had a colon tumor removed they got it all but has stage 3 colon cancer 6 of 20 lymph nodes what does this mean?

An excellent website: I am sorry to hear your news. You obviously have been going through a lot. The nih has an excellent, patient friendly website with info about this. See: http://www.Cancer.Gov/cancertopics/pdq/treatment/colon/patient/page2 the site goes on to discuss treatment. He is most likely looking at chemotherapy. Your oncologist should be able to help with the details. Good luck to you both. ...Read more

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I was diagnosed with stage 3 colon cancer, I'm on folfox6. I read cq10 will help in stopping cancer sells from growing. Take it while chemo? Dosage?

I do not agree: What is cq10? Do you mean coq10? There is nothing other than your chemo that can help prevent your cancer from growing or progressing. But chemo you have taken gives you a very good chance of staying cancer free. I would not fool around with anything else. ...Read more

Dr. Mark Pack
13 Doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dr. James Dukelow
12 Doctors shared insights

Colonic (Definition)

This is a combining term referring to some condition, treatment or disease of the colon. Such as colonic enema, colonic ...Read more