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Doctor insights on: Stage 1 Renal Cell Carcinoma Furmans 2

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Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?

Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?

Yes but: It could possibly spread to local lymph node but the chances are very low. The lymph nodes that are in thoracic cavity are even less likely to contain metastatic tumor from a stage 1a endometrial cancer, especially if it's a garden variety low grade lesion. In fact, long term survival is very good, like 95%. The other 5% may represent very high grade tumors. ...Read more

Dr. Barry Rosen
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Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is the difference between: basal cell carcinoma epithelioma, squamous cell carcinoma, and melanoma?

Skin cancer: The difference between basal cell carcinoma, squamous cell carcinoma, and melanoma has to do with how the skin cancer cells appear under the microscope as well as how they behave. Therefore it is important that they be diagnosed and treated as quickly as possible by a healthcare professional who specializes in this area. ...Read more

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Dear sir, my mother was suffering from brest cancer and her reports are metaplastic carcinoma with spindling &squamous metaplasia grade 3 suggest me?

Dear sir, 
my mother  was suffering from brest cancer and her reports are
metaplastic carcinoma with spindling &squamous metaplasia grade 3  suggest me?

Rare Breast Cancer: Metaplastic breast cancer is quite rare, representing less than 1% of all breast cas. It is so-named based upon its microscopic appearance. While the tendency is for these to be "aggressive" cancers, treatment and survival are based on the cancer stage, just like any other breast cancer. Once your mother recovers from her surgery, she will be referred to a medical oncologist for rx planning. ...Read more

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Is bone marrow transplantation is curative for chronic myeloid leukemia caused by (Philadelphia chromosome) ?

Is bone marrow transplantation is curative for chronic myeloid leukemia caused by (Philadelphia chromosome) ?

Yes: In 70 to 80 percent of cases. The availability of tyrosine kinase inhibitors such as gleevec (imatinib) has moved transplant to 3rd line treatment ...Read more

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Is there acinar cell loss in type 2 diabetes ?

Is there acinar cell loss in type 2 diabetes ?

See below: The reason why acinar cells become atrophic is not clear, most evidence points to an important role of Insulin as a trophic agent, although other factors including autoimmunity against exocrine tissue and vascular damage (microangiopathy) cannot be excluded. ...Read more

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Colon resection for ca showed 2 lymph nodes involved. What are chances of ca spreading to cirrhortic liver?

Colon resection for ca showed 2 lymph nodes involved.  What are chances of ca spreading to cirrhortic  liver?

Can occur..: But hopefully your colon cancer was found before it could spread to the liver. Colon cancer can spread to the liver in any person, irregardless if you gave cirrhosis or not. See your oncologist to evaluate what the best treatments may be for your specific condition. Blood testing and x-ray tests such as ct, mri, or pet scans are indicated for some people. ...Read more

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Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done

Survival rate for triple neg receptors for early stage breast cancer after chemo treatment?  No lymph nodes involve, stage 1b, grade 2, mastec done

Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read more

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Can a patient stage 1 papillary thyroid cancer with BRAF mutation positive live more than 20 years ( she is 51 years old) ? Thank you very much!

Yes: Papillary thyroid cancer is very common and some people do not even know they have it as small tumors may be found on autopsy when they die of something else. Generally tumors are graded by how ugly they look to the pathologist and how far they've spread. Your tumor has also been molecularly characterized. There are new treatment options available. Please discuss with your oncologist. ...Read more

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End stage liver disease, what is the prognosis?

End stage liver disease, what is the prognosis?

Not good.: When a liver with cirrhosis is having trouble doing it's job, it's called end-stage liver disease. This means that the liver is beginning to fail. Generally, patient in this setting will die or need transplant within a few years. Having cirrhosis, however, is not the same as end stage liver disease. Only when the liver starts to fail do we call it end stage. ...Read more

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Can cyberknife surgery be used for squamous cell carcinoma?

Can cyberknife surgery be used for squamous cell carcinoma?

Cyberknife is: Not surgery, not a knife..It is a linear accelerator placed on a robotic arm to deliver stereotactic radiotherapy in high but very accurate arcs or beams to ablate anatomic abnormalities. It does not care about cell type. You need to discuss if it is appropriate for your sq ca; what the alternatives are; adverse effects; cost; who pays. ...Read more

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2 kids with nonimmune hydrops, 1 f 2 1/2 yrs, 1 m 3 months?

2 kids with nonimmune hydrops, 1 f 2 1/2 yrs, 1 m 3 months?

Hydrops fetalis, : Excessive fluid build-up in 2 or more body parts in a fetus, can be pretty severe, as you describe. Non-immune hydrops can be from heart or lung problems, severe anemia (alpha-thalassemia or infections), genetic syndromes or problems in fetal development. I'd seek evaluations of both kids by a geneticist to look for a cause ; by your state's early intervention program to assess their development. ...Read more

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I was Diagnosed with Severe Dysplasia(CIN3)involving ectocervical squamous mucosa and fragments of benign endocervical glandular epithelium. ?

I was Diagnosed with Severe Dysplasia(CIN3)involving ectocervical squamous mucosa and fragments of benign endocervical glandular epithelium. ?

Cervical Cancer: CIN3 is a high risk precursor to cervical cancer and needs to be treated and followed up. Local procedures like LEEP or cone biopsy are important to exclude possible occult invasion. Follow-up following those with visual exam, pap and HPV testing to exclude recurrence or residual are vital. Visual exam to exclude HPV disease of vagina or vulva are also important. ...Read more

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What is an inhomogenous spleen in hodgkin's lymphoma?

What is an inhomogenous spleen in hodgkin's lymphoma?

An homogenous: You mean a scan report an homogenous spleen in hodgkins lymphoma ? Then it is a normal spleen , the disease did not involve the spleen, good news. ...Read more

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Is SIRT worth doing for liver liver metastases 1x 7 cm 1x 6 cm 8 under 2 cm?

Is SIRT worth doing for liver liver metastases 

1x 7 cm
1x 6 cm
8 under 2 cm?

Yes: Multiple liver lesions can be treated by a number of approaches because what is in liver will not spread. Originally ligation of hepatic artery was used since portal vein supplies hepatocytes and hepatic artery the metastatic tumors.Can be used with SIRT which is a form of RT treatment wherein a dose of SIR-Spheres® microspheres are delivered up to 40 times higher than conventional doses. ...Read more

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Last yr CT scan n yesterday abd ultrasound shows diffuse hepatocellular disease in liver. Prognosis, treatment, further testing? Crohns patient

Last yr CT scan n yesterday abd ultrasound shows diffuse hepatocellular disease in liver. Prognosis, treatment, further testing? Crohns patient

Crohn's complication: Many Crohn's complications. Granulomatous hepatitis (non infectious) And Amyloidosis of liver two rare but known problems. Please see your gastroenterology specialist soon. This could be due to some drug as well, such as sulfasalazine. Check Alkaline Phosphatase levels. ...Read more

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Dr. Terence Chapman
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