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Doctor insights on: St John Wort Vs Prozac

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How long do u have to wait to start taking St. John wort after being on 10 mg prozac (fluoxetine)?

How long do u have to wait to start taking St. John wort after being on 10 mg prozac (fluoxetine)?

Prozac (fluoxetine) has a: long half-life and doesn't work its way into the nervous system at the proper depth to begin to alter mood for about 14 to 21 days, in most cases. Some folks think a month is not too long to wait. (This is not the same as the initial "rush" some patients experience as the drug first is introduced...) Quitting Prozac (fluoxetine) takes about the same time to leave the body, so give it 2+weeks to be safe. ...Read more

Dr. Heidi Fowler
1,040 doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Took 20mg of Prozac (fluoxetine) for 8 mos. Been off for two weeks.Can i now take st. Johns wort. Didnt like side effects of prozac (fluoxetine)?

Probably: Prozac (fluoxetine) will stay in your system for 4-6 wks & st johns is a weak maoi which theoretically could b a problem but st. John's is so weak i've had pts who've taken it with their antidepressants including Prozac (fluoxetine) with no problems. ...Read more

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Would like to switch to st.Johns wort from 20mg of Prozac (fluoxetine) because of side effects been on Prozac (fluoxetine) for 8 mos. How soon could I do this?

Would like to switch to st.Johns wort from 20mg of Prozac (fluoxetine) because of side effects been on Prozac (fluoxetine) for 8 mos. How soon could I do this?

Thirty-Five Days: Every medication has a half-life. This is the time it takes the body to eliminate one half of the med. I consider a medication to be eliminated after 5 half-lives. When the body begins to breakdown prozac, (fluoxetine) one of the byproducts is an active metabolite that has a half-life of 7 days. It takes about 35 days for total elimination. One should not take st. John's wort until Prozac (fluoxetine) is eliminated. ...Read more

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What do you recommend if i take 20mg of prozac( fluoxetine) evert day for depression; yesterday i bought some st johns wort (5000mg tablets), can what do you recommend if i take them together?

What do you recommend if i take 20mg of prozac( fluoxetine) evert day for depression; yesterday i bought some st johns wort (5000mg tablets), can what do you recommend if i take them together?

Why?: If you are not happy with prozac, (fluoxetine) talk to your doctor. If you are not happy with your doctor, get another doctor. I don't understand why you bought st. John's wort before you know what to do with it? The issue here is not whether combining Prozac (fluoxetine) with st. John's wort is good idea for you. The even more important problem is how to repair your relationship with your doctor. ...Read more

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Is st john wort also effective for OCD or gad when compared to ssris like fluoxetine?

Is st john wort also effective for OCD or gad when compared to ssris like fluoxetine?

No: In my experience st. Johns wort hasn't helped any of my OCD clients although many have tried. I wish it would be but ive not seen it. ...Read more

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What is the name of an anti-depressent that isn't Prozac (fluoxetine) or st john's wort?

Many: Please do not use St John's Wort as an antidepressant, the quantity and quality of the active ingredient in these preparations are unreliable and can be very dangerous. Fluoxetine (Prozac) is in the SSRI class as are citalopram, escitalopram and sertraline among others. SNRI class contains duloxetine and venlafaxine. Bupropion is in its own class. There are others such as tricyclics and MAOIs. ...Read more

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Could st. Johns wort effect my blood sugar?

Could st. Johns wort effect my blood sugar?

Yes, Sugar effects: Extensive research supports the safe use of St. John's wort for a short duration ( ...Read more

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Is it safe to use st.John wort with cipralex?

Is it safe to use st.John wort with cipralex?

No: No, i would not recommend combining st. John's wort with cipralex (escitalopram). The 2 have somewhat similar effects on serotonin, and the combination could result in more side effects than you bargain for. The cipralex is much more focused and measured than the st. John's wort. ...Read more

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Can I take losec (omeprazole) and st johns wort at the same time?

Can I take losec (omeprazole) and st johns wort at the same time?

Yes, but...: St. John's wort will speed up the rate that your liver breaks down losec (omeprazole). So combining both medications will reduce the effectiveness of losec (omeprazole). ...Read more

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Does St.Johns wort decrease the effect of the morning after pill?

Does St.Johns wort decrease the effect of the morning after pill?

Nonconclusive: Some studies have shown that St John's wort speeds up the metabolism of estrogen and progesterone. But others do not confirm that finding. Also the dosage of St Johns Wort is not standardized. So there is no way of telling what effect it will have. ...Read more

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Can i start Zoloft (sertraline) 24 hours after taking st john wort?

Can i start Zoloft (sertraline) 24 hours after taking st john wort?

I would encourage: You not to take both these compounds together . I usually recommend taking an antidepressant over st johns' wort because in this country, herbals are not well regulated. In europe - herbals are treated like other medications ; are regulated. ...Read more

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Ok so im gonna try to kick my depression in the *** for good! i heard from someone that the medicine st john wort really works. Does it?

Ok so im gonna try to kick my depression in the *** for good! i heard from someone that the medicine st john wort really works. Does it?

It can be helpful : For mild depression. Talking therapy is really important for making real life changes. Cognitive behavioral therapy can be very effective for the treatment of depression. Whether you elect to take st johns wort or not - you owe it to yourself to get help. Look for a psychologist in your area. In the mean time, drink at least 64 ounces of water per day & be aerobically active daily. Good luck. ...Read more

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I take alprazolam 0.50 when needed to (usually 2 to 3 times a month). Are there none interactions with that drug and st johns wort or 5-htp daily?

I take alprazolam 0.50 when needed to (usually 2 to 3 times a month). Are there none interactions with that drug and st johns wort or 5-htp daily?

St. John's Wort may: decrease effects of Alprazolam; may interact with 5-HTP (5-hydroxytryptophan) to increase risk of a rare but serious condition called serotonin syndrome; and may interact with some foods. These interactions may mimic anxiety/panic attacks. Consult prescriber regarding all medications and supplements to determine what is best for your situation. Best regards for good health and well-being. ...Read more

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What happens if I take st johns wort?

What happens if I take st johns wort?

Potent herbs: This can elevate the mood much like a synthetic selective serotonin reuptake inhibitor, and some say it's a good adjunct to the process of learning how to maintain a happy, productive attitude through insight and practice. It's also likely to sensitize your skin to sunlight and may make your hands tingly. Always let your physicain know if you take it. ...Read more

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What amount st. johns wort is too much?

No good studies yet: Different studies have examined different doses, and different companies put different recommendations on their bottles; you've probably noticed. The stuff seems quite safe used judiciously, and some people do wel on higher doses, but it's very dangerous combined with prescription SSRI's, and is a famous sun-sensitizer. ...Read more

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Can you die when overdosing on st john wort.?

Can you die when overdosing on st john wort.?

Don't try: It's one of the best, if not the most useful, of the herbals. The great concern is that it might contribute to serotonin syndrome especially if combined with other things such as other antidepressants, meperidine, and/or cocaine. No deaths yet, but you don't want to be the first. ...Read more

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Can GABA and st johns wort be combined?

GABA: No direct harmful effect that I am aware of. ...Read more

Dr. Alan Ali
761 doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more