Doctor insights on:
Spruce T201 Ige
IgE: In serum measures the level of IgE circulating in the blood stream, it is the immunoglobulin that binds to the surface of certain cells, mast cells and basophills, and responsible for acute type I allergic reactions. IgE measures the amount of circulating IgE not the bound IgE, it is elevated in certain diseases ...Read more
Genetics: The tendency to make more ige in response to foreign substances that enter the body (aka allergens) is inherited. Allergies and parastic infections are the common reasons why people develop high ige levels. There are some rare disorders associated with increased risk of infections associated with very high levels of ige. A board-certified allergist can help sort this out for you. ...Read moreSee 1 more doctor answer
See Below: Total IgE reference range varies with age and normals are established for individual reference labs as well. Typically in an adult a normal level is,less than 150, but it is not uncommon for patients with allergies to have levels in 500-600 range and patients with eczema can go to levels in the 1000-2000 range. Really high IgE, like 5000 and up can indicate immune system disease or parasite ...Read more
No: People vary tremendously in IgE levels. There's still little knowing what it means. How does Junior feel? ...Read more
Yes but why?: Unless you have an illness which demands the treatment, there is no reason to lower the ige level since the options are not devoid of major side effects. ...Read more
Are you saying an IgE of zero means imunodeficiency? Are there any additional testing recommendations.
I was told I have a total IgE level of 1, 795. Is this significant? Is it higher than normal? What health risks are associated with it?
IgE: The ige level you mention is total allergic antibody level circulating in your body. It is quite high. Depending on normal values of each lab, a normal one is usually less than 200. High ige associate with several allergic conditions. The most common ones are allergic rhinoconjunctivitis or hay fever, asthma, eczema.... Certain infections can drive a high level of ige like that too. ...Read more
Can Be...: Elevated total serum IgE is seen in mainly allergic diseases like allergic rhinitis and eczema. It is also seen in some primary immunodeficiencies, parasitic and viral infections, certain inflammatory diseases, and some malignancies. Atopic conditions like allergic rhinitis and eczema definitely have a genetic component to them. ...Read moreSee 1 more doctor answer
Yes: Treatment of atopic disease, such as atopic dermatitis or asthma, can result in lowered IgE. The B-cells that make IgE depend on certain signals in the body to live and produce antibody. Time, changes in environmental/food/drug exposure, medicating specific diseases can all result in decreases in both total and specific IgE levels ...Read moreSee 1 more doctor answer