Doctor insights on:
Spindle Cell Lipoma Treatment
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
May i know the simple explanation for this diagnosis: (post auricular area), excision biopsy: cellular spindle cell lesion favor nodular fascitis?
Get 2nd opinion: A pathologist who trained at one of my institutions self-diagnosed a sarcoma and had his arm amputated, only to discover later it was nodular fasciitis, which is very benign. I was trained by some of the great pathologists and even they said they'd never call nodular fasciitis without a second pathologist agreeing. I'd suggest showing 3-4 of us pathologists. Good luck. ...Read more
Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?
Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more
Yes it often is: Spindle cell cancers are often called sarcomas. They can arise either in the soft tissues or in the bones. Ask your doctor what is the name of your cancer? If it is a sarcoma, chemotherapy is useful in about half of the cases, often it is used in conjunction with surgery and radiotherapy. ...Read more
What mean of pap smear test?Superficial, intermediate squamous cell ,metaplastic and endocervical cell seen..Many cell with kilocytic atypia seen.
Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?
Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more
Potentially serious: A nonseminomatous germ cell tumor is a malignancy that has multiple origins within the testicle. It is less common, but potentially more serious, than seminomas of the testicle. Early and aggressive treatment is necessay and can lead to cure in many patients that present with limited disease. Systemic chemotherapy is now available for patients that present with advanced tumors. ...Read more
Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read moreSee 1 more doctor answer
Potentially serious: Signet ring adenocarcinoma can occur in the stomach, intestine, or in other organs. The stage of cancer is most important in terms of prognosis, and how serious a cancer is. However, signet ring carcinomas are generally more aggressive than non-signet ring adenocarcinomas. ...Read more
Yes: It may be curable but you will need and extensive work up and close follow up with your otolaryngology surgeon (ent). Depending on the extent of cancer treatment may consist of any combination of surgery, radiation, and chemotherapy. Maintaining your nutrition and mental health during this time would be very important as well. ...Read moreSee 3 more doctor answers
Depends upon stage: Early stage disease is usually treated by surgical resection. More advanced disease is usually treated by combination of chemotherapy and radiation therapy and stage 4 disease is usually treated with chemotherapy alone or consideration of hospice for those with significantly far advanced disease. ...Read more
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