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Doctor insights on: Spindle Cell Carcinoma Of The Breast

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Dr. Bryan Wu Dr. Wu
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What's the chromosome number of infiltrating ductal carcinoma?

Dr. Bryan Wu Dr. Wu
1 doctor agreed:
What's the chromosome number of infiltrating ductal carcinoma?

Depends on grade: The level of chromosomal aberrations in infiltrating ductal carcinoma is correlated with the grade of the cancer cells. "grade" means the microscopic appearance and corresponds with how closely the cancer cells try to form normal breast structures. High grade or poorly differentiated infiltrating ductal carcinomas tend to have more chromosomal abnormalities than non-high grade carcinomas. ...Read more

Dr. Barry Rosen
4,369 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is the difference between: basal cell carcinoma epithelioma, squamous cell carcinoma, and melanoma?

Skin cancer: The difference between basal cell carcinoma, squamous cell carcinoma, and melanoma has to do with how the skin cancer cells appear under the microscope as well as how they behave. Therefore it is important that they be diagnosed and treated as quickly as possible by a healthcare professional who specializes in this area. ...Read more

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Non-small cell carcinoma and small cell carcinoma. What is the difference?

Non-small cell carcinoma and small cell carcinoma.  What is the difference?

Small cell. all else: Small cell cancer of the lung is a specific kind of cancer that has uniform, small cells. Non small cell cancer is the term for all other cancers that are in the lung, like adenocarcinoma, squamous cell cancer, and large cell cancer. These are grouped this way due to treatment approach. Small cell presents as widely disseminated and gets chemo., while non small cell is localized, gets surgery. ...Read more

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Describe the features of basal cell carcinoma.?

Describe the features of basal cell carcinoma.?

Non-healing ulcer: Basal cell carcinoma may present as an indolent, non-healing ulcer with spread to contiguous tissues. There may be nodules, pigment changes, bleeding and tissue destruction. ...Read more

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Malignant neoplasm of the breast which spread to the lung. The lung cancer is what type?

Malignant neoplasm of the breast which spread to the lung. The lung cancer is what type?

Same: With metastasis the distant lesion usually is the same histology -pathology as the primary. So breast adenocarcinomas will be the cell type in the chest- lung in the case cited. ...Read more

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Whats the classification of breast cancer metastasis?

Whats the classification of breast cancer metastasis?

Staging: Breast cancer staging is described as t (tumor size), n (lymph node metastases) and m (metastases to sites like bone, lung, etc). In a simplified short answer: stage 0 is non-invasive breast cancer, stage 1 is no spread to lymph nodes, stage 2 and stage 3 has lymph node spread and larger tumors, and stage 4 would have metastases to other organs. ...Read more

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What is the difference between squamous cell carcinoma and basal cell carcinoma?

What is  the difference between squamous cell carcinoma and basal cell carcinoma?

Different origins: Skin cancers are named for the type of skin cell that they develop from. A basal cell is generally a less dangerous tumor unless it is near an opening such as the nose, eye or ear. The squamous cell is more serious, requires a more aggressive surgical removal, and will sometimes spread inside the body (metastasize). ...Read more

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What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

Location: What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma. ...Read more

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Please describe the survival rates of small cell lung cancer?

Please describe the survival rates of small cell lung cancer?

Limited: Most with this diagnosis have less than 2 years of survival, unless found when small and peripheral so it can be removed! ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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What are stages of squamous cell carcinoma?

What are stages of squamous cell carcinoma?

Differentiated: The pathology report will desribe well, moderate or poorly differentiated. Well differentiated is less advanced. It will also describe depth on invasion and whether nerves are involved. An evaluation of lymph nodes is done to confirm squamous cell is localized to skin. In advanced cases it will have spread requiring surgery followed by radiation, and possible chemotherapy. ...Read more

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Describe the purpose of a keratinized stratified squamous cell (keratinocyte).?

Describe the purpose of a keratinized stratified squamous cell (keratinocyte).?

Skin: These cells form our skin and other "barrier" tissues. Specifically the palms and soles are great examples! ...Read more

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Is stage 4 squamous cell carcinoma of the head and neck always incurable?

Is stage 4 squamous cell carcinoma of the head and neck always incurable?

No.: Stage iva head and neck cancer is usually curable. If it is confined to the primary site (example base of tongue) and spread only to neck lymph nodes, it can be cured with radiation/chemo, sometimes surgery added. ...Read more

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Can squamous cell cancer begin in the brain?

Can squamous cell cancer begin in the brain?

Yes: It is rare, and when it is truly primary rather than having spread from the ear or metastasized from the lung, it has begun in a dermoid cyst in a person with partial absence of the corpus callosum. ...Read more

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What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more

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What are squamous cell carcinoma, basal cell carcinoma, and melanoma?

What are squamous cell carcinoma, basal cell carcinoma, and melanoma?

Types of cancer: Malignant melanoma is a type of cancer that originates from the melanocytes. It often travels to distant locations in the body and is the deadliest form of skin cancer. Basal cell carcinoma rarely travels to other parts of the body, but will recur locally if not treated appropriately. Squamous cell carcinoma rarely travels to other parts of the body. ...Read more

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Dr. Liawaty Ho Dr. Ho
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What is the survival percentage non small cell lung cancer?

Dr. Liawaty Ho Dr. Ho
6 doctors agreed:
What is the survival percentage non small cell lung cancer?

The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read more

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What percentage of atypical hyperplasia becomes breast cancer?

What percentage of atypical hyperplasia becomes breast cancer?

Small percentage: In a recent study in the annals of surgical oncology, they looked at how many surgical excisions performed for atypical hyperplasia displayed either dcis or cancer. Out of the cases that the study reviewed, only about 1% of the cases upstaged to either dcis or cancer. ...Read more

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