Top
20
Doctor insights on: Spina Bifida Karyotype

Share
1

1
What is spina bifida?

What is spina bifida?

Spinal cord disorder: The spinal cord forms as an open tube that starts to close from the middle out to the two ends. The entire closure is done by about ten weeks. If the closure is not normal than a condition known as spina bifida occurs. Open spina bifida is when there is an opening in the spinal column to the skin. Closed spina bifida is when there is an opening in the spinal column but it has a thin cover. Read more

See 2 more doctor answers
Dr. Edward Smith
224 Doctors shared insights

Spina Bifida (Definition)

A birth defect involving incomplete development of the spinal cord or its coverings. The exact cause of the condition is unknown, but a risk factor appears to be low levels of folic acid in a woman's body before ...Read more


2

2
What is spina bifida?

What is spina bifida?

Spina Bifida: Spina bifida is a birth defect where the spine does not close around the spinal cord during development. This may be as small as a small gap between the 2 sides, with no buldging out of membranes or nerves, & no associated handicaps, to a large defect with part of the cord exposed outside the body, leading to paralysis and other neurological problems. Folic acid decreases the risk. Read more

See 1 more doctor answer
3

3
Is spina bifida hereditary?

Studies show that: The incidence of neural tube defects (NTD's) like open Spina Bifida would decrease by 70% if all women took 0.4mg of Folic Acid daily from menarche to menopause. However, this dose does not prevent NTD's in offspring of women with variations in several genes involved in folate (folic acid) & homocysteine metabolism. There are also inheritable genetic causes of NTD's that are not related to folate (folic acid) metabolism. Read more

4

4
Who discovered spina bifida?

Although depictions: Of people with Spina Bifida go back 12, 000 years, Amsterdam's Dr. Nicholas Tulp named the disorder between 1618-1652. Dr. Giovanni Battista Morgagni an Italian, linked lower-limb deformity & hydrocephalus to Spina Bifida in 1761. Studies show that the incidence of NTD's could decrease by as much as 70% if all women were to take a daily Folic Acid supplement from menarche to menopause. Read more

5

5
Do you deal with spina bifida?

Yes: Yes, but rarely. This condition is not common and as a family physician, I see only what comes my way. Spina bifida is usually approached in a team concept, usualy dealing with a primary care doctor (pediatrician, family physician or internest) along with physical therapist, neurologists, neuro-surgeons, physiatrist (physical medicine specialists) and a host of others. There are many issues. Read more

See 4 more doctor answers
6

6
What are the signs of spina bifida?

Spina Bifida: Depends on the type;
1. Spina bifida occulta shows small gap in 1 or more of spinal bones, seen in newborn as a small dimple or birth mark or tuft of hair or fat collection.
2. Meningocele shows as bulging of meninges (sheath around spinal cord) through the opening in back.
3. Myelomeningocele is wider protrusion through several vertebrae, forming a large sac. This is most severe. Read more

7

7
What are the tests for spina bifida?

What are the tests for spina bifida?

Spina bifida: Spina bifida is usually diagnosed by x-ray for MRI of the lower spine. In the new born it can also be done with an ultrasound. Read more

See 2 more doctor answers
8

8
Can you tell me what spina bifida means?

Split spine.: Spina bifida is a generic term used to describe congenital malformations of the spine (typically lower spine). It can be mild to very severe and be associated with a variety of conditions. Read more

9

9
What can you tell me about spina bifida?

Spina bifida: Spina bifida is a very generic term that covers a lot of disorders of the spine that occur at birth. These can range from defects in the spinal bone to loss of the muscle and skin covering leading to herniation of the spinal cord and roots. There are a wide variety of causes known. Read more

10

10
Later side afects of occult spina bifida?

Later side afects of occult spina bifida?

No: Spina bifida occulta results from failure of the two lamina of one vertebra to make a solid bony fusion. The defect is generally bisecting the spinous process vertically. No instability is present. No neurologic dysfunction is present because neural elements are not affected. But associated neurological problems which may be symptomatic are more common in association with spina bifida occulta. Read more

See 2 more doctor answers
11

11
How many forms of spina bifida are there?

How many forms of spina bifida are there?

Many: Embryonic development involves progressive closure of the neuro cord which becomes the spine. This closure may be slightly incomplete (occult) or remain a cyst (meningomyelocele) or remain completely open. In some the pelvis and anus do not develop properly. Nerves to bladder, bowel, and legs may only partially develop. The brain may not develop properly, and hydrocephalus may develop. Read more

See 2 more doctor answers
12

12
How do you deliver baby with spina bifida?

As usual: Delivery of a neonate with spina bifida may require some special attention by the obstetrician, but usually the delivery progresses as normal and the spina bifida is addressed after delivery. Read more

See 1 more doctor answer
13

13
What is spina bifida and how is it caused?

Congenital: This is a failure of the bones to fuse at birth usually in the lower spine. Sometimes the nerves to the legs and bladder are also malformed. So in effect, you are born with it. Read more

14

14
How can spina bifida impact someone's life?

To what degree?: If you are talking about spina bifida occulta, there will be no impact. If you are talking about cases with neurologic symptoms, it depends on whether lower nerve roots (sacral) are involved or if spinal cord is involved. People with spinal cord lesions are more susceptible to life-altering events than are those without. Read more

See 1 more doctor answer
15

15
Could my nephew have spina bifida if I did?

Could my nephew have spina bifida if I did?

Unlikely: Spina bifida (there are several types) is associated with some known genetic defects however the majority of cases are spontaneous and most cases are more likely related to folate (folic acid) deficiency during pregnancy. The general answer is that this is unlikely to occur in your nephew. Read more

See 1 more doctor answer
16

16
How can occult spina bifida impact a persons life?

How can occult spina bifida impact a persons life?

No impact: Spina bifida occulta is manifested by a single defect: failure of the two laminae of a vertebra to achieve bony union with each other. Often times the spinous process is associated with one lamina. Rarely is the spinous process completely absent. The vertebra has normal strength, normal associated joints, ligaments, qnd disks plus no nerve root herniation or compression. Occult = symptom-free. Read more

17

17
Can you tell me any of the history of spina bifida?

Spina bifida: Are you asking about the history of spina bifida in the historical literature or the history of patients that present with spina bifida? If you are talking about the written history of spina bifida there a number of good historical research papers that can be easily found on Google or other search engines. Read more

18

18
How old does someone with spina bifida usually live?

Live into the Adulth: With modern treatment and medical care these children live into the adulthood these days. Read more

See 1 more doctor answer
19

19
Can you tell me any thing about occult spina bifida?

Spina bifida: "occult" is a term used when the finding of spina bifida is only seen on an x-ray and it is a lack of development of a bone called the lamina in the lower lumbar spine that does not fully develop. In most cases there are usually no clinical problems associated with this x-ray finding. Read more

20

20
What type of inheritance is involved in spina bifida?

What type of inheritance is involved in spina bifida?

Multifactorial: Isolated spina bifida (myelomeningocele) is a neural tube defect along with anencephaly that exhibits multifactorial determination--a combination of many genes and in utero environmental factors that cross a threshold to produce the defect. A couple having a child with spina bifida or anencephaly has a ~2% risk for each future pregnancy, a risk decreased by preconception folic acid. Read more

See 1 more doctor answer