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Doctor insights on: Spina Bifida Karyotype

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What is spina bifida?

What is spina bifida?

Spinal cord disorder: The spinal cord forms as an open tube that starts to close from the middle out to the two ends. The entire closure is done by about ten weeks. If the closure is not normal than a condition known as spina bifida occurs. Open spina bifida is when there is an opening in the spinal column to the skin. Closed spina bifida is when there is an opening in the spinal column but it has a thin cover. ...Read more

Dr. Edward Smith
224 Doctors shared insights

Spina Bifida (Definition)

A birth defect involving incomplete development of the spinal cord or its coverings. The exact cause of the condition is unknown, but a risk factor appears to be low levels of folic acid in a woman's body before ...Read more


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What is spina bifida?

What is spina bifida?

Spina Bifida: Spina bifida is a birth defect where the spine does not close around the spinal cord during development. This may be as small as a small gap between the 2 sides, with no buldging out of membranes or nerves, & no associated handicaps, to a large defect with part of the cord exposed outside the body, leading to paralysis and other neurological problems. Folic acid decreases the risk. ...Read more

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Is spina bifida hereditary?

Studies show that: The incidence of neural tube defects (NTD's) like open Spina Bifida would decrease by 70% if all women took 0.4mg of Folic Acid daily from menarche to menopause. However, this dose does not prevent NTD's in offspring of women with variations in several genes involved in folate (folic acid) & homocysteine metabolism. There are also inheritable genetic causes of NTD's that are not related to folate (folic acid) metabolism. ...Read more

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Who discovered spina bifida?

Although depictions: Of people with Spina Bifida go back 12, 000 years, Amsterdam's Dr. Nicholas Tulp named the disorder between 1618-1652. Dr. Giovanni Battista Morgagni an Italian, linked lower-limb deformity & hydrocephalus to Spina Bifida in 1761. Studies show that the incidence of NTD's could decrease by as much as 70% if all women were to take a daily Folic Acid supplement from menarche to menopause. ...Read more

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Do you deal with spina bifida?

Yes: Yes, but rarely. This condition is not common and as a family physician, I see only what comes my way. Spina bifida is usually approached in a team concept, usualy dealing with a primary care doctor (pediatrician, family physician or internest) along with physical therapist, neurologists, neuro-surgeons, physiatrist (physical medicine specialists) and a host of others. There are many issues. ...Read more

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What are the signs of spina bifida?

Spina Bifida: Depends on the type;
1. Spina bifida occulta shows small gap in 1 or more of spinal bones, seen in newborn as a small dimple or birth mark or tuft of hair or fat collection.
2. Meningocele shows as bulging of meninges (sheath around spinal cord) through the opening in back.
3. Myelomeningocele is wider protrusion through several vertebrae, forming a large sac. This is most severe. ...Read more

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What are the tests for spina bifida?

What are the tests for spina bifida?

Spina bifida: Spina bifida is usually diagnosed by x-ray for MRI of the lower spine. In the new born it can also be done with an ultrasound. ...Read more

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Can you tell me what spina bifida means?

Split spine.: Spina bifida is a generic term used to describe congenital malformations of the spine (typically lower spine). It can be mild to very severe and be associated with a variety of conditions. ...Read more

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What can you tell me about spina bifida?

Spina bifida: Spina bifida is a very generic term that covers a lot of disorders of the spine that occur at birth. These can range from defects in the spinal bone to loss of the muscle and skin covering leading to herniation of the spinal cord and roots. There are a wide variety of causes known. ...Read more

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Later side afects of occult spina bifida?

Later side afects of occult spina bifida?

No: Spina bifida occulta results from failure of the two lamina of one vertebra to make a solid bony fusion. The defect is generally bisecting the spinous process vertically. No instability is present. No neurologic dysfunction is present because neural elements are not affected. But associated neurological problems which may be symptomatic are more common in association with spina bifida occulta. ...Read more

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How many forms of spina bifida are there?

How many forms of spina bifida are there?

Many: Embryonic development involves progressive closure of the neuro cord which becomes the spine. This closure may be slightly incomplete (occult) or remain a cyst (meningomyelocele) or remain completely open. In some the pelvis and anus do not develop properly. Nerves to bladder, bowel, and legs may only partially develop. The brain may not develop properly, and hydrocephalus may develop. ...Read more

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How do you deliver baby with spina bifida?

As usual: Delivery of a neonate with spina bifida may require some special attention by the obstetrician, but usually the delivery progresses as normal and the spina bifida is addressed after delivery. ...Read more

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What is spina bifida and how is it caused?

Congenital: This is a failure of the bones to fuse at birth usually in the lower spine. Sometimes the nerves to the legs and bladder are also malformed. So in effect, you are born with it. ...Read more

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How can spina bifida impact someone's life?

To what degree?: If you are talking about spina bifida occulta, there will be no impact. If you are talking about cases with neurologic symptoms, it depends on whether lower nerve roots (sacral) are involved or if spinal cord is involved. People with spinal cord lesions are more susceptible to life-altering events than are those without. ...Read more

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Could my nephew have spina bifida if I did?

Could my nephew have spina bifida if I did?

Unlikely: Spina bifida (there are several types) is associated with some known genetic defects however the majority of cases are spontaneous and most cases are more likely related to folate (folic acid) deficiency during pregnancy. The general answer is that this is unlikely to occur in your nephew. ...Read more

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How can occult spina bifida impact a persons life?

How can occult spina bifida impact a persons life?

No impact: Spina bifida occulta is manifested by a single defect: failure of the two laminae of a vertebra to achieve bony union with each other. Often times the spinous process is associated with one lamina. Rarely is the spinous process completely absent. The vertebra has normal strength, normal associated joints, ligaments, qnd disks plus no nerve root herniation or compression. Occult = symptom-free. ...Read more

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Can you tell me any of the history of spina bifida?

Spina bifida: Are you asking about the history of spina bifida in the historical literature or the history of patients that present with spina bifida? If you are talking about the written history of spina bifida there a number of good historical research papers that can be easily found on Google or other search engines. ...Read more

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How old does someone with spina bifida usually live?

Live into the Adulth: With modern treatment and medical care these children live into the adulthood these days. ...Read more

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Can you tell me any thing about occult spina bifida?

Spina bifida: "occult" is a term used when the finding of spina bifida is only seen on an x-ray and it is a lack of development of a bone called the lamina in the lower lumbar spine that does not fully develop. In most cases there are usually no clinical problems associated with this x-ray finding. ...Read more

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What type of inheritance is involved in spina bifida?

What type of inheritance is involved in spina bifida?

Multifactorial: Isolated spina bifida (myelomeningocele) is a neural tube defect along with anencephaly that exhibits multifactorial determination--a combination of many genes and in utero environmental factors that cross a threshold to produce the defect. A couple having a child with spina bifida or anencephaly has a ~2% risk for each future pregnancy, a risk decreased by preconception folic acid. ...Read more

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How can you support a family member with spina bifida?

Help them: To reach their fullest potential. Be alert for changes in functional status, as these can be signs of more serious problems. Lastly make sure they are followed at a multidisciplinary clinic as these patients get the best care there. ...Read more

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What is the definition or description of: Spina bifida?

Spina bifida: Spina bifida is a neural tube birth defect. It is causing defects in spinal cord & bones of spine. See: http://www. Mayoclinic. Org/diseases-conditions/spina-bifida/basics/definition/con-20035356 ...Read more

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For how long have people been affected by spina bifida?

Spina bifida: Spina bifida is an ancient disease with many anthropological specimens that show this disease has been around pretty much as long as man has evolved. ...Read more

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How much time have people been affected by spina bifida?

Spina bifida: Spina bifida has been around as long as humans have been on this earth. They are a number of ancient specimens that have been discovered at burial sites around the world. ...Read more

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Can you tell me the history and disease of spina bifida?

Spina bifida: Spina bifida is a disease of many manifestations with the most common being a case of lumbo sacral myelomeningocele. This is a situation where the child is born with the spinal cord exposed in the lower back. This disorder develops during pregnancy and the use of folic acid in the diet has reduced incidence quite significantly. There are several good web sites that have info available. ...Read more

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What is my risk of having another baby with spina bifida?

What is my risk of having another baby with spina bifida?

Complex question: This question is difficult to answer without additional information such as the type of spina bifida you baby has, the presence of any other abnormalities and a complete family history. Most cases of isolated spina bifida are sporadic and are not strictly inherited. For a more precise answer, you can seek a genetic evaluation (geneticist/genetic counselor). ...Read more

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Need expert help here. What are all types of spina bifida?

Spina bifida: It would take a textbook to answer this question as they are many types and severity. In short spina bifida can be mild with no skin stigmata such as spina bifida occulta. To the more severe disorder where this is actual herniation of the spinal cord through the skin and muscle and again there are both mild and severe forms of this. ...Read more

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What is the natural course/history of untreated spina bifida?

What is the natural course/history of untreated spina bifida?

It Depends: It depends on the extent of the spina bifida. Some forms of spina bifida are mild and only involve more of the superficial bony elements of the lumbar spine. Other forms of spina bifida may be more extensive involving not only the bony elements of the spine but also the coverings of the neural elements and the neural elements themselves. Natural history is dependent on the form of spina bifida. ...Read more

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Help please? How does spina bifida affects someones childhood?

Depends: Spina bifida occulta is a congenital skeletal and therefore musculoskeletal abnormality. It is more a predisposing factor, meaning some people will have problems due to it while others will not. One should remain active but try to find activities that do not aggravate or predispose to pain. ...Read more

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Common problems arising from a child of ten having spina bifida?

Depends: Urinary incontinence and constipation, of course. That is lifelong. Problems due to insensitivity of the skin, specifically the bottoms of the feet if the child is able to walk. The extent of the problems depends on the level of the lesion. Lumbosacral? Throacolumbar? Thoracic? ...Read more