Doctor insights on:
Speckled Ana Test Results
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
What does this mean ?
SSB(La)IGG Positive 85
SSA(Ro)AB IGG Neg.
SED RATE Neg.
Depends: All lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that antibodies to SSA suggest auto-immune disorder, however, if that is the only abnormal test and you do not have any symptoms, I would leave it alone and re-evaluate in six months. ...Read more
Probably not: Likely false positive test. There must be at least 4 major criteria. ...Read more
How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more
Not much by itself: The ANA result needs to be interpreted in conjunction with your history, signs and symptoms. Speckled pattern is common. You can a positive ANA from a variety of conditions besides autoimmune disease. Discuss the results with the doctor who ordered the test. Meanwhile it's too soon to be worried about it. ...Read more
See below: Both of these are low values and should not be used for a specific diagnosis. However, the most important feature is why were these labs drawn. For example what symptoms you were having to have the labs drawn and in that case they may mean slightly more, but just looking at the labs they are low values and dont point to one specific disease. ...Read more
4/5 results- test neg scl70, double stranded dna, ssa, ssb, smith rmp sederate, esr&crp norm, electrolyte/white/red blood norm.Again + ANA 1:160 centromer. What additional test to exclude scleroderma/crest?
Positive Ana and dsdna. Retest showed neg ana and dsdna, but low c4. What does the low c4 mean? Were first results false positive?
Complex: sample handling, timing and transport are important, the process is delicate and constitutes multiple steps at different temperatures, and the results are interpreted in context with the clinical picture, just ask your doctor / rheumatologist for interpretation, if just suspicion, observation and follow up are the way to go for many clinicians, wish you wellness ...Read more
What tests did they do?
-rpr, rfx qn rpr/confirm tp-pa
value (normal range
non reactive (non reactive
Misinformed?: Who told you that your hep c test was false? If you have no viral load that means you cleared an infection. Are you sure you are getting the right advice? ...Read more
Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?
Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more
Positive ana positive rnp low positive ccp positive dsdna can you tell me if this means lupus or mctd?
?: depends on the clinical picture as well, results point towards auto immune disorder, but need to be put in clinical context and follow up to commit to a diagnosis ...Read more
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