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Doctor insights on: Spastic Paraparesis Of The Lower Limbs

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What is the definition of hereditary spastic paraparesis?

What is the definition of hereditary spastic paraparesis?

Hereditary SP: Hsp, is a genetic disorder transmitted as autosomal dominant, meaning one of the parent has the disease in order to pass it to the offspring. It is a progressive spasticity in the legs , may be associated with hypertonic urinary incontinence, seizure, dementia, or peripheral neuropathy. ...Read more

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Dr. Janice Alexander
5 doctors shared insights

Partial Paralysis Of Lower Limbs (Definition)

Paraparesis is a clinical finding in which an individual has weakness or spasticity (rigidity) of the lower ...Read more


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What is tropical spastic paraparesis?

Disorder of sp cord: A subacute condition with impairment of lower extremity >upper extremity function, sensory abnormalities, bladder functioning and girdling lumbar pain. About 80 % of patients with tsp have antibodies to htlv-1 (not aids virus..Htlv-3) the disorder and similar disorders were described in caribbean patients. ...Read more

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What is hereditary spastic paraparesis?

Rare condition: Progressive leg weakness and spasticity (tightness and catching of leg with flexion), caused by autosomal dominant and recessive or x-linked genetics, with usual slow progression and normal life span. Mri may demonstrate atrophy of brain and/or spinal cord. ...Read more

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Any treatment for heriditary spastic paraparesis? Accompanied by sensory neuropathy?

Any treatment for heriditary spastic  paraparesis? Accompanied by sensory neuropathy?

Symptomatic treatmen: Hsp is a group of inherited disorders, often insidiously progressive and severe. There are no effective treatments to the underlying damage to the nerve axons so treatment is symptomatic. Baclofen, dantrolene and tinazidine may help with spasticity; oxybutinin with urinary urgency; gabapentin, Pregabalin and duloxetine for neuropathy. Vitamins, d, e and b6 may also help. Physical therapy also. ...Read more

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What can I do about my hereditary spastic paraparesis?

What can I do about my hereditary spastic paraparesis?

Treat the symptoms: If the process is stable, and not progressing, best to try anti-spasticity meds, such as baclofen, tizanidine, or even a pump. Botox injections, although off-label, might be useful. Acupuncture has promise. Splints, braces, exercises all may help. If legal in your state, medical marijuana may help, as the research from europe suggests benefit in the spasticity associated with ms. ...Read more

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I have severe spasticity in my lower left limb due to a tbi. A split tendon transfer is not an option, is an amputation a plausible next step?

I have severe spasticity in my lower left limb due to a tbi. A split tendon transfer is not an option, is an amputation a plausible next step?

Unlikely.: It sounds like your spasticity is so tight that it is focal rigidity and is refractory to other treatments. Although the answer is complicated, for brevity, it is unlikely that spasticity producing pain, skin breakdown, or some other secondary effect will require an amputation. In addition, if pain is a problem, you may end with phantom pain thus compounding your problem. ...Read more

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I have spasticity in my lower limb from a tbi. I tried oral and injectable drugs. Split tendon transfer is not an option. I'm active. Thoughts on amputation?

I have spasticity in my lower limb from a tbi. I tried oral and injectable drugs. Split tendon transfer is not an option. I'm active. Thoughts on amputation?

Need to adapt: You have a permanent deficit. Many children with cerebral palsy learn to live with their disability and are active and participate in regular sports and activities. You now have a form of acquired cerebral palsy. Learn to adapt to it. A good therapy program will help, and trained therapists can be sure that you have the best bracing and stretching methods to provide optimal outcome. ...Read more

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For lower limb spasticity, are there any other injectables available besides Botox? I also do not like the idea of the baclofen pump.

For lower limb spasticity, are there any other injectables available besides Botox? I also do not like the idea of the baclofen pump.

A couple approaches: Several oral meds may work well for spasticity, such as tizanidine, dantrolene sodium, even diazepam. BOTOX is approved by FDA for upper limb but not yet for lower limb. Baclofen outside of pump is mediocre, but coming soon is long-acting form which will make all the difference (might try Amrix for time being). Also, try physical therapy, biofeedback, acupuncture. ?medical marijuana? ...Read more

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Paralyzis and hyperalgesia in one limb initiated 2 weeks after scoliosis surgery. sphincter incont Clonus. Spasticity. upper motor neuron lesion? why?

Paralyzis and hyperalgesia in one limb initiated 2 weeks after scoliosis surgery. sphincter incont Clonus. Spasticity. upper motor neuron lesion? why?

Postop complication: One has to worry about a delayed postoperative complication-significant!!!! Need to see operating surgeon . Potential causes would be hematoma(blood) compressing spinal cord or even a spinal cord lesion remote from operative site ...Read more

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Extremity (Definition)

Is appendage or body part that extends from the main body, such as arms or ...Read more