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Doctor insights on: Sorafenib

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Is nexavar (sorafenib) prescribed for hepatocellular carcinoma?

Is nexavar (sorafenib) prescribed for hepatocellular carcinoma?

Yes, for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more

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What r the chances of getting back renal cell carcinoma for an old male (63 yrs) after being cured by nephrectomy & taking nexavar (sorafenib) ?

What r the chances of getting back renal cell carcinoma for an old male (63 yrs) after  being cured by nephrectomy & taking nexavar (sorafenib) ?

It depends: This is not an easy answer, because it depends upon the stage of your original tumor and your surgical pathology. I would ask this question of your urologist or oncologist, who know the specifics of your case. ...Read more

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Dr. Liawaty Ho Dr. Ho
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How effective iressa (gefitinib) for lung cancer after chemo?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
How effective iressa (gefitinib) for  lung cancer after chemo?

Only if ..: Gefitinib will only work if there is a egfr mutation detected on the cancer. It will not be effective if there is no egfr mutation detected. ...Read more

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How effectice is Xeloda (capecitabine) for metastatic breast cancer?

How effectice is Xeloda (capecitabine) for metastatic breast cancer?

Quite effective: Xeloda (capecitabine) is quite an effective drug and has been used in metastatic breast cancer. The response will be higher when it is combined with other chemotherapy agent- with additional possible side effects. Discuss further with you oncologist in detail. ...Read more

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Is Xeloda (capecitabine) effective for breast cancer?

Is Xeloda (capecitabine) effective for breast cancer?

Xeloda (capecitabine) for breast ca: Xeloda (capecitabine) also known as Capecitabine is a very effective oral chemotherapy drug used for metastatic or stage 4 breast cancer. It can be used by itself (mono therapy) or as part of combination chemotherapy. Major side effects include diarrhea, hand foot syndrome, nausea and small chance of coronary spasm. It is well tolerated. Patients on Xeloda (capecitabine) need to be followed closely by medical oncologists. ...Read more

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How effective is Xeloda (capecitabine) for metastatic breast cancer?

How effective is  Xeloda (capecitabine) for metastatic breast cancer?

It depends: As the first treatment for metastatic breast cancer, Xeloda (capecitabine) works in 40-60% of people treated. If it is the second, third or later treatment after failure of other agents, the effectiveness is much less. ...Read more

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

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What is Gemzar (gemcitabine)?

What is Gemzar (gemcitabine)?

Gemzar (gemcitabine): "Gemzar is used to treat cancers of the pancreas, lung, ovary, and breast. See: http://www.drugs.com/gemzar.html ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Is stage IV metastatic cancer treatable?

Is stage IV metastatic cancer treatable?

Depends: Some cancers are curable with today's chemotherapy even if they have spread extensively. Others (for example, the common lung cancers) may someday be curable when they have reached stage iv, but not today. I've just seen reports of possible cures of stage IV colon and stomach cancers; i'm hopeful. ...Read more

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How effective is gemcitabine (Gemzar) for treating lung cancer?

How effective is gemcitabine (Gemzar) for treating lung cancer?

Mildly: Gemzar (gemcitabine), (gemcitabine) a form of chemotherapy can be used in non resectable lung cancer. It usually follows a couse of standard chemo such as Platinum/Taxol. When used in pancreatic Ca it is given with Abraxane, a form of Taxol which enhances Gemzar (gemcitabine) by a few weeks. After tumors respond to chemo which affects the tumor DNA, stem cells resistant to chemo reappear. Better results are now seen with anti PD-1. ...Read more

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Nexavar (sorafenib) is useful in multi concetric haptoma?

Nexavar (sorafenib) is useful in multi concetric haptoma?

Nexavar (sorafenib): Nexavar (sorafenib) is a targeted therapy that can block the ability of tumor to recruit blood vessels and stop the tumor from growing. This can be used in conjunction with locoregional therapy (chemoembolization) in certain situations or on its own. ...Read more

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Are the cancer drugs, gefitinib and tarceva (erlotinib) available?

Are the cancer drugs, gefitinib and tarceva (erlotinib) available?

While gefitinib was: Developed first, it is hard to find in america (iressa (gefitinib)). Erlotinib (tarceva) has more side effects, but a trial showed a survival advantage. Probably more related to the characteristics of the study participants than the drug. These are small molecule, tyrosine kinase inhibitors in the erb family of receptors. Canada and europe has iressa (gefitinib). Erlotinib is in us. ...Read more

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How effective is regorafenib for colon cancer mets?

How effective is regorafenib for colon cancer mets?

Depends: One study showed a response rate of 40%. "Response" in this context, means the tumor shrunk. It is rare for tumors to disappear on regorafenib. Clinical benefit depends to a great extent on the overall fitness of the patient (performance status), extent of disease, and number of prior therapies. Courage and faith, Marilyn994, and my best wishes for you. ...Read more

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Whats imatinib mesylate?

Whats imatinib mesylate?

Enzyme inhibitor: This drug, gleevec, (imatinib) is used to treat chronic myeloid leukemia and gastro-intestinal stromal tumors. It acts by inhibiting and enzyme produced by tumor cells. ...Read more

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Is stage IV pancreatic cancer terminal?

Is stage IV pancreatic cancer terminal?

Yes?: As a rule, stage 4 cancer of the pancreas is incurable. As to being terminal, it depends on the definition. If you mean it will kill the patient at some point, the vast majority of the times the answer is yes. If you mean it will kill the patient right away, it depends on the situation. Never say never, though, some patients have surprised me in the past. Sorry if it is about you or a loved one. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Has anyone taken Xeloda (capecitabine) or zometa for mets?

Has anyone taken Xeloda (capecitabine) or zometa for mets?

These are 2 options: Xeloda (capecitabine) - is an oral chemotherapy drug that can be used for certain metastatic cancers alone or in combination with other chemotherapy drugs as palliative treatment. Zometa - is used in a situation where cancer has spread to the bones. Its not chemotherapy but a bisphosphanate, a medication used to prevent further weakening of bones by cancer and prevent fractures. In some situations both are given. ...Read more