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Doctor insights on: Soluble Transferrin Receptor

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What do transferrin levels mean?

What do transferrin levels mean?

Transferrin is a…: …blood plasma protein that delivers 2 iron ions from absorption centers to all tissues, especially for the production of hemoglobin. Low tf may be a liver defect (where it's made) or a kidney problem allowing excessive loss. Decreased plasma tf can lead to iron overload diseases such as hemosiderosis. Increased tf binds free iron, leading to anemia. Discuss lab results with your doc. ...Read more

Receptor (Definition)

An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more


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Is magnesium fat or water soluble? Is taking too much toxic? How do I know when to stop as tests are not very indicatve right?

Is magnesium fat or water soluble? Is taking too much toxic? How do I know when to stop as tests are not very indicatve right?

Magnesium=necessary: Magnesium is a water soluble mineral that most people are whole-body deficient in. At high doses, it causes diarrhea. If the kidneys are compromised in any way, the dose needs to be lower and monitored by a physician. A RBC magnesium level is the most useful test as serum magnesium is kept at a very steady level. Magnesium is necessary to 300+ reactions in the body. ...Read more

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Why does diarrhea feel like dying? It literally feels like a massive burning, painful, nauseating, weakness sensation. Does soluble fiber prevent it?

Why does diarrhea feel like dying? It literally feels like a massive burning, painful, nauseating, weakness sensation. Does soluble fiber prevent it?

Consider the source: When we have the runs we loose electrolytes, i.e., sodium potassium, magnesium, and it makes us feel week and unfocused. That's why people are encouraged to drink lots of fluids--so they don't dehydrate in the process. Fiber is more of a treatment than prevention. Best to see your doc to find the source. Peace and good health. ...Read more

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My iron levels came back 21 low, transferrin 352.0 normal, tibc 492.8 high, saturation 4.3 % low. Would this be normal anemia?

My iron levels came back 21 low, transferrin 352.0 normal, tibc 492.8 high, saturation 4.3 % low. Would this be normal anemia?

Iron deficiency Anem: Looks like you have iron deficiency anemia but the confirmatory test is 'ferritin' level in the blood being low. Talk to your doctor to know why you have this. You either may be bleeding from your gut or due to your menses (excess). ...Read more

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What's meaning of low transferrin saturation?

What's meaning of low transferrin saturation?

Iron deficiency: Until proved otherwise. The body has made protein, probably extra, to carry iron that isn't available. ...Read more

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What's meaning of low transferrin saturation?

Iron deficiency: Until proved otherwise. The body has made protein, probably extra, to carry iron that isn't available. ...Read more

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My iron (or transferrin) saturation rate tested 111%, is this a fatal level?

My iron (or transferrin) saturation rate tested 111%, is this a fatal level?

Just get treated: This is very suspicious for hemochromatosis. Of all the killer diseases, this is by far the easiest to keep totally under control. Don't be afraid. Man up. You'll probably be just fine -- and when we start treatment, you'll soon be surprised how much better you feel. ...Read more

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What does a low result for unbound IBC mean? My iron, transferrin saturation and IBC are all wnl.

Nothing: Reference ranges are set so that several percent of healthies arbitrarily fall outside. If you are otherwise well and have no signs of an iron problem on either end, ignore it. ...Read more

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Cbc is ok, but iron is 56, transferrin is 400, total ibc is 500, uibc is 444, iron %trans sat is 11. What could this mean?

Cbc is ok, but iron is 56, transferrin is 400, total ibc is 500, uibc is 444, iron %trans sat is 11. What could this mean?

Iron deficiency: Iron deficiency is often symptomatic long before anemia / abnormal CBC appears. Many physicians do not know this. Other body systems become iron-depleted and this may have something to do with why you describe chronic fatigue. I trust your physician has looked for ways you might be losing iron in additon to your monthly loss, and will replace as appropriate. ...Read more

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Ferritin 4.6, iron 27, transferrin saturation 6, tibc 437. . . Is everything is low why is tibc high? What does this mean? What do I do now?

Iron binding: Capacity. Tibc is the abbreviation for total iron binding capacity. When iron is low the iron binding capacity is high and vice versa. Given your diagnoses, it would be prudent to consult your doctor for next steps. However, you have iron deficiency and may take over the counter iron supplements. ...Read more

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Recent blood test has Transferrin saturation 6% and I have been advised that this is extremely low. What does the Transferrin saturation mean/do?

Recent blood test has Transferrin saturation 6% and I have been advised that this is extremely low. What does the Transferrin saturation mean/do?

Low iron: Transferrin transports iron in the body. Low saturation means that your body doe not have enough iron. Please follow your doctor's advise about taking iron supplements. See this site for more info on this topic.
http://www. Mayoclinic. Org/diseases-conditions/iron-deficiency-anemia/basics/definition/CON-20019327
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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My Iron level is 79, IRON BINDING CAP is 258, TRANSFERRIN SAT % is 31. But my FERRITIN level is 792 and I'm slightly anemic could I have hemochromatos?

My Iron level is 79, IRON BINDING CAP is 258, TRANSFERRIN SAT % is 31. But my FERRITIN level is 792 and I'm slightly anemic could I have hemochromatos?

Yes: Just on the basis of the serum ferritin. It's worth following. Chronic inflammation in the body can also raise ferritin. Are you symptomatic? Your anemia would of course be due to some other factor. One common secnario is a healthy young man with mild anemia actually has thal minor. Do you? It still gets missed in the 21st century. Not an emergency. Keep up with the workup. ...Read more

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What do transferrin levels mean?

Transferrin is a…: …blood plasma protein that delivers 2 iron ions from absorption centers to all tissues, especially for the production of hemoglobin. Low tf may be a liver defect (where it's made) or a kidney problem allowing excessive loss. Decreased plasma tf can lead to iron overload diseases such as hemosiderosis. Increased tf binds free iron, leading to anemia. Discuss lab results with your doc. ...Read more

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What is the definition or description of: transferrin?

What is the definition or description of: transferrin?

Carries iron: This protein is the major carrier of iron atoms in the blood. It tends to run high in iron deficiency and rather low when there's liver disease or bad longlasting infection. The percent of transferrin molecules ("saturation") that carry an iron atom is a good way of spotting iron deficiency or overload if the patient hasn't recently popped an iron pill. ...Read more

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Any idea why my transferrin is dropping?

Any idea why my transferrin is dropping?

Maybe: Low transferrin may be due to a malfunction of your live, rwhere it's made, or a kidney defect that allows excessive loss through your urine. Have your doctor fully evaluate the problem. ...Read more

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Is a transferrin saturation of 23% low for a man?

Is a transferrin saturation of 23% low for a man?

You're fine: 15-50% is a pretty good range for a man. Wondering why you asked, and glad you're taking a proactive approach to your health. ...Read more

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What do low transferrin levels mean on your lab results?

What do low transferrin levels mean on your lab results?

Transferrin is a…: …blood plasma protein that delivers 2 iron ions from absorption centers to all tissues, especially for the production of hemoglobin. Low tf may be a liver defect (where it's made) or a kidney problem allowing excessive loss. A patient with decreased plasma transferrin can suffer from iron overload diseases such as hemosiderosis. Discuss lab results with your doc. ...Read more

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How long do results take for the beta 2 transferrin test of my nasal fluid?

How long do results take for the beta 2 transferrin test of my nasal fluid?

Depends: The test itself can be done in one day. However, most hospitals need to send the sample to a reference lab and due to low volume the lab may not run the test every day.
Wish you good health. ...Read more

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What does a bit low serum iron and low transferrin mean in ferritin is normal?

Eat a healthy diet: What is your hemoglobin level? If hemoglobin is normal and ferritin is normal, there may not be anything to worry about. Eat a healthy diet rich in fresh vegetables, fruits, whole grains, nuts, beans, legumes, lentils, and small amounts of lean meats. Avoid saturated fats. Exercise 30 minute/day for about 5 days/wk. ...Read more

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Is a transferrin saturation of 20% and iron 71 mcg/dl low for a 35 years old man?

Is a transferrin saturation of 20% and iron 71 mcg/dl low for a 35 years old man?

Probably normal: The normal range for transferrin saturation in adults is 20-50%, therefore a value of 20% is at the lower end of the normal spectrum. The serum iron reference range is 55–160 mcg/dl in men, therefore a value of 71 mcg/dl is within normal limits. ...Read more

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I have hemochromatosis but my iron levels are Ferritin 8 Iron 7 Transferrin 2.1 Transferrin Sat 13?

Being treated?: The goal of management of hemochromatosis is to reduce one's body iron load as reflected in numbers such as these. Hemochromatosis is deadly if untreated, but easier than any other very serious illness to treat effectively. I'm glad the diagnosis was made. ...Read more

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My serum iron is elevated at 32umol/L and transferrin sat 58%. Could this be haemochromotosis? Would it cause symptoms?

My serum iron is elevated at 32umol/L and transferrin sat 58%. Could this be haemochromotosis? Would it cause symptoms?

Maybe: You might also have just eaten a big steak or taken a multivitamin pill with iron. Look at the big picture. Any doubt, a serum ferritin is your next lab, and of course your transaminases on your chemical profile. Arthritis at the base of the thumb is often the first sign. If it's hemochromatosis, no big deal. Among all the common killers, it's the easiest by far to keep totally under control. ...Read more

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Transferrin saturation test was done without fasting and in the afternoon. Will it help to diagnose hemochromatosis? I was told fasting was not needed

Correct: It's a pretty good screen for hemochromatosis, but if you're really worried -- you have elevated liver enzymes, or a family history, or imaging findings -- get a serum ferritin and/or a HFE gene study in addition. ...Read more

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My iron levels came back 21 low, transferrin 352.0 normal, tibc 492.8 high, saturation 4.3 % low. Would this be normal anemia?

Iron deficiency Anem: Looks like you have iron deficiency anemia but the confirmatory test is 'ferritin' level in the blood being low. Talk to your doctor to know why you have this. You either may be bleeding from your gut or due to your menses (excess). ...Read more

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Iron is 225. TOT. Iron bind cap is 473. Transferrin is 47.6 Hemoglobin is 9. hematocrit is 30.6. B12 is 476. what could be the cause?

Iron is 225. TOT. Iron bind cap is 473. Transferrin is 47.6 Hemoglobin is 9. hematocrit is 30.6. B12 is 476. what could be the cause?

Need to examine: You are not deficient in iron or B12. Do you lose too much blood in menstruation? Could you have a hemolytic anemia? It is not feasible to provide a meaningful opinion without taking additional history, physical examination and may be some tests. It would be prudent to see your doctor.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex.
Get HPV vaccine, if you are under 27 years of age. ...Read more

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19 months old baby has ferritin 7 (22-291) iron 61 (40-100) ibcu 470 (110-370) tibc 531 (228-428) transferrin % saturation 11 (14-57) RBC 19.8 (12-16)?

Iron deficiency: Your toddler has iron deficiency and should be getting some replacement. Discuss with your pediatrician. There are different multivitamin otc you can consider as a supplement. ...Read more

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My serum iron was elevated at 241, however my ferritin, TIBC, and transferrin count were in the normal reference ranges. Is this hemochromatosis?

Donate blood: What you described is not necessarily hemochromatosis. There is a genetic for it that you may wish to get in consultation with your doctor. If you are otherwise healthy consider donating blood, it will reduce your iron and you will do a good deed. See this site for more info.
https://www. Nlm. Nih. Gov/medlineplus/ency/article/003488.htm ...Read more

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My son is athlete 18 and seems healthy. TIBC- 242 UIBC 120 but serum iron-122 iron sat- 50 ferritin-107 transferrin-226 EOS-7. improved since 2013?

My son is athlete 18 and seems healthy. TIBC- 242 UIBC 120 but serum iron-122 iron sat- 50 ferritin-107 transferrin-226 EOS-7. improved since 2013?

Need more info: Without some context - the reason these labs were obtained, previous values, and any treatments - it is difficult to address your post. ...Read more

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My iron level is 59, ubc is 325, tibc is 384 and transferrin sat is 15.4. Are these normal?

Normal for females: Normal values for females are. Iron level 50to1170ug/dl. Tibc 250to370.Transferin saturation 15to50 percent. Your values look low normal but seem to me within normal range but you did not mention other values like hemoglobin which is important to know, if I have to guess it will be low normal and may meds to be followed. ...Read more

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What does this mean as a blood test: transferrin?

What does this mean as a blood test: transferrin?

Transferrin is a…: …blood plasma protein that delivers 2 iron ions from absorption centers to all tissues, especially for the production of hemoglobin. Low tf may be a liver defect (where it's made) or a kidney problem allowing excessive loss. Decreased plasma tf can lead to iron overload diseases such as hemosiderosis. Increased tf binds free iron, leading to anemia. Discuss lab results with your doc. ...Read more

Dr. Robert Isaacs
215 Doctors shared insights

Transferrin (Definition)

This protein is the major carrier of iron atoms in the blood. It tends to run high in iron deficiency and rather low when there's liver disease or bad longlasting infection. The percent of transferrin molecules ("saturation") that carry an iron atom is a good way of spotting iron deficiency or overload if the patient hasn't recently ...Read more