Doctor insights on:
Soft Tissue Sarcoma With Metastasis To Lung
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
Mom had breast cancer in 2006 & in 2009 metastasis to lung, brain&eye happened. On 2012 tumor spread to bones and liver. Now she can't move easily&tired?
Fatigue: I would suggest getting in touch with a palliative care specialist. Your mom may benefit from optimizing her medications and improving her symptom and pain control. They can also help give advice for your social situation in helping taking care of her. She may benefit from inpatient or outpatient hospice. ...Read more
It depends...: You need to know the size and grade of your sarcoma or what was the name given to it. The prognosis is good for smaller tumors (less than 5cm) and for low/intermediate grade sarcoma. But if it was over 5 cm and high grade then there is substantial risk for relapse; so close surveillance is advised. ...Read more
A soft tissue sarcoma is a cancer of the soft tissues (like muscle or tendon or other soft tissue)
an ultrasound is an imaging test using ultrasound waves to look into your body, seeing through the soft tissues, and seeing the edges of bones.
Your doctor is evaluating a bump you or they are feeling. An MRI might come next. ...Read more
Variable: Most patients with soft tissue sarcomas can be cured and have a normal life span. Even in cases where sarcoma had spread, cure can sometimes be achieved. In cases where it cannot be cured, patients may live from weeks to years. It depends on the sarcoma type and the patient. Nobody can predict survival of any one patient. We only know statistics for large groups. ...Read more
How curable is a soft tissue sarcoma of the calf? Expected disease free life expectancy and treatment options?
Surgery +/- RT: Most soft tissue sarcomas of the extremities are treated with surgery to completely remove the cancer ("negative" margins) then possibly also post-surgery radiation therapy or rt. Prognosis, and the need for rt, depends on the tumor type and grade, or how aggressively it is growing under the microscope. ...Read more
Very hard...: To describe. Some are fibrous sarcomas and some are fatty liposaromas. Generally are hard, firm, gritty, gray-yellow rounded densities. Can infiltrate other tissues or can push other normal tissues away. Feels and looks differently than surrounding normal tissues. ...Read more
Painless mass: Most soft tissue sarcomas are painless masses. Usually, they will grow in size. Some subtypes, like synovial sarcoma, can be painful. Other reason for pain is compression or invasion of nerves and blood vessels. Most painless masses will turn out to be lipomas, which are benign, but a sarcoma has to be ruled out. To sum it up, a painless mass is a sarcoma until proven otherwise. ...Read more
Surgery +radiate: The main therapy for soft tissue sarcoma is complete surgical resection with negative (i.e. Clean) surgical margins. Depending on the type and grade of sarcoma, radiation therapy after surgery may also be indicated. Chemotherapy is generally only given if the sarcoma has spread to distant sites. ...Read more
Surgery +/-radiation: In general sarcomas are treated with surgical removal with negative margins which means that the tumor doesn't go up to the edge of the specimen in any area. Depending on the sarcoma type, surgical results, and sarcoma grade, radiation therapy after the surgery may be given. Chemotherapy is reserved for advanced cases. ...Read more
Supportive tissue: Sarcomas are non epithelial tumors arising in every part of the body. They arise in muscle, and subcutaneous tissue as well as retroperitoneum. Tissue of origin is fat, muscle, fibrous supportive tissue, nerve, blood vessel and other structures. In viscera they come from the muscle tissue of the stomach, uterus and blood vessels and classified as leiomyosarcoma. ...Read more
Sarcoma specialist: Per NCCN guidelines, patients should be diagnosed and managed at a multidisciplinary sarcoma center when possible. Type of sarcoma is critical. If tumor is localized, surgery and radiation are recommended with chemotherapy generally for patients for patients with intermediate or high grade tumors larger than 5 cm. Chemotherapy is the mainstay of therapy for patients whose tumors have spread. ...Read more
3 irregular lobular mass with slight subcutaneous edema above massconcern for soft tissue sarcoma. Possibly synovial cell. What exactly does this mean?
Histology: Sarcoma can be found in the soft tissues of the breast. It is identified after biopsy of a tumor, by the pathologist looking under the microscope, doing special immunostains, and potentially genetic fish testing for chromosomal translocations. It is important that a pathologist experienced with sarcoma review the slides to cement the diagnosis. ...Read more
Soft tissue cancer: Sarcomas are cancers that affect the cells that are part of the support structure of our bodies. The more common type of cancer, adenocarcinomas, start in glands of the body, like breast, colon, lung, etc. But sarcomas start in bone, fat, muscles, ligaments and some parts of the skin, . ...Read more
Painless mass: Most soft tissue sarcomas, with few exceptions like synovial sarcoma, are painless. Patients and even some doctors are falsely reassured by the absence of pain. Sarcomas may grow quickly or very slowly, but any painless mass has to be evaluated appropriately. While a painless mass can turn out to be a benign lipoma, a sarcoma has to be ruled out. An MRI can readily diagnose a lipoma. ...Read more
Yes: Fibromatosis, while it doesn't have "sarcoma"in the name is actually a low-grade sarcoma. However, this only applies to cases occurring in the abdomen. Less commonly, these tumors can occur on the extremity. Cases of Palmar and Plantar fibromatosis are not aggressive and generally behave in a benign fashion. Have your sarcoma pathology checked by an expert david. [email protected] Com ...Read more
Rarely.: If you are talking about a plain, standard, old-fashioned x-ray, soft tissue sarcoma rarely appears because these types of x-rays are really designed to evaluate bones. Soft tissue sarcomas are usually fleshy and better evaluated with ct scans (a different kind of x-ray), or mri. Sarcoma that has spread to the lungs can be see on a plain chest x-ray thought. ...Read more
Nature of tumor: That's just the way sarcomas behave. It is not known why. Most soft tissue sarcomas spread through the blood stream. Most metastases, if present, are found in the lungs. Bone and other soft tissues are less frequent sites. Some soft tissue sarcomas go though lymphatics (synovial sarcoma, clear cell sarcoma and angiosarcoma). And sometimes cancer doesn't follow rules and spreads as it wishes. ...Read more
Other tests better: A precise diagnosis of a malignant soft tissue tumor typically cannot be made with ultrasound. Low grade sarcomas may not be able to be differentiated from lipomas on US. Definitive diagnosis can only be made with biopsy. If you have a concern, see your surgeon for consideration of excision or biopsy. ...Read more
Yes, but rarely: If the sarcoma is hidden by normal tissues, you will not feel a lump. For example in the thigh, where there are lots of muscles, the sarcoma will not be felt until it is quite large. In the pelvis, it is even worse. The sarcoma may be picked up incidentally if imaging is done for other reasons. If the sarcoma affects nerves or vessels, it may present itself due to pain before a mass is felt. Otherwise, most sarcomas are painless. ...Read more
See a specialist: Surgery is the mainstay of treatment. There are only a few hundred surgeons in the us trained to treat sarcomas. Initial appropriate treatment by a specialist is crucial as incorrect resection may lead to severe morbidity and even amputation. Radiation and possibly chemotherapy are often also needed. After that, frequent follow up is needed to detect if tumor returns or spread. ...Read more
By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
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