Doctor insights on:
Small Fiber Peripheral Neuropathy
Definitions: Small fibers which mediate pin and temperature sensations lack myelin, and are indeed pure axons, so the terms small fibre neuropathy or axonopathy are synonymous. Polyneuropathy usually refers to a larger fibre process which is distal bilateral and symmetrical, and can be either axonal or schwann cell predominant, and affects strength, balance, proprioception, and light touch. ...Read moreSee 2 more doctor answers
A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more
Yes: Sensory symptoms of small fiber neuropathy are highly variable. Common complaints include paresthesias, dysesthesias, and insensitivity to pain. Paresthesias are abnormal sensations. They are often described as numbness, burning, cold, prickling, pins and needles along with other symptoms. ...Read more
DEFINITIONS: Peripheral neuropathy is generic term for abnormal nerves in limbs. Many of these involve large fibers which can cause weakness, numbness, imbalance. The small fiber neuropathy presents with pain, decrease in pin and temperature sensation and caused by a limited number of conditions. Both large and small fibres may be involved in peripheral nerve disorder. ...Read moreSee 1 more doctor answer
↑glucose most common: basis neuropathy; Google: "peripheral neuropathy etiology", yet many other associations exist, note word association; Why? Data about associations; mechanisms not fully understood. Cholesterol is part of every animal cell, enables cell membrane flexibility & has never been correct issue despite promotioin by NIH.gov as surrogate for Lipoproteins. Hi odds stress/anger/fear an issue; more complex. ...Read more
Possibly: The prevalence of neuropathy among patients with celiac disease is much higher than in healthy people. Sometimes, the neurological problems arise from nutritional deficiencies due to malabsorption. However, some cases are due to autoimmunity and associated with the underlying disease (Celiac). ...Read more
Maybe in part: We are increasingly learning that small fibre neuropathies are common, especially associated with diabetes, but also present even in some fibromyalgia cases. A medical food metanx, may result in increased nerve fiber density in the skin after 6-12 months. If the cause is due to an immune polyneuritis, ivig can reverse much of it. Need to understand causation to treat successfully. ...Read more
Good question: This type of neuropathy is associated with tingling and numbness, of the hands and feet. Often a neurologist will do a nerve conduction test and it will be negative. This is because the nerves effected are very small and cannot be picked up with this test. There is a good test to DX this: skin biopsy looking at nerve fiber density. Look for a neurologist specializing in neuropathy; they do this. ...Read moreSee 1 more doctor answer
Peripheral neuropath: Small fiber neuropathy is a peripheral neuropathy that occurs from damage to small unmyelinated nerve fibers present in skin, peripheral nerves, and organs.The role of these nerves is to innervate the skin (somatic fibers) and help control autonomic function (autonomic fibers). It is estimated that 15-20 million people in the USA have some form of peripheral neuropathy. ...Read more
Yes: In some cases, marked benefits occur with infusions of ivig, and we know that diabetics who take metanx experience fibre re-growth and multiplication after about 9-12 months. If problem due to treatable condition such as celiac disease or sarcoid, might also see reversal. Uncover the precise mechanism of the disorder, and treat appropriately. ...Read more
See below.: Peripheral neuropathy has to do with sensation or lack of sensation of peripheral nerves: often in feet, legs and hand. Autonomic neuropathy has affects the autonomic nervous systems which control involuntary body functions such as control of blood vessel size, sweating etc. ...Read more
Emg study of feet reads a fairly symmetric mild sensorimotor peripheral neuropathy with primarily axonal loss features. liver, sugar clean.Thoughts?
Axonal PN: Axonal peripheral neuropathy is an illness that may cause numbness and weakness affecting the feet, legs and sometimes the hands. In this condition the nerve cells (axons) that transmit information become ill. Common causes of this condition are hormonal and blood chemistry disorders...... http://www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropathy.htm ...Read more
Small Fiber Neuro: Spinal cord stimulator has been shown to be effective in treating a number of chronic pain situations such as chronic pain, such as failed back surgery syndrome, complex regional pain syndrome, ischemic and coronary artery disease. There is also a case report showing the successful treatment of small fiber neuropathy with spinal cord stimulation from georgetown university. ...Read more
Mixed motor sensory peripheral neuropathy in both legs. ncs also found ulnar neuropathy both elbows. what disease can cause this?
An approach: We approach peripheral neuropathy etiology by blood and urine testing, but can focus our tests based on whether this is an axonal or Schwann cell involvement, which your EMG-NCS should have indicated if done properly. Most common causes in USA are diabetes, and nutritional deficiency, associated with alcohol. Worldwide, may well be leprosy or HIV. ?Concierge? ...Read more
- Talk to a doctor live online for free
- What are the causes of small fiber peripheral neuropathy?
- Small fiber neuropathies
- Small fiber sensory neuropathy
- Ask a doctor a question free online
- Idiopathic small fiber neuropathy
- Causes of small fiber neuropathy
- Autoimmune small fiber neuropathy
- What is small fiber neuropathy?
- Talk to a neurologist online