Doctor insights on:
Small Fiber Neuropathy Prognosis
Definitions: Small fibers which mediate pin and temperature sensations lack myelin, and are indeed pure axons, so the terms small fibre neuropathy or axonopathy are synonymous. Polyneuropathy usually refers to a larger fibre process which is distal bilateral and symmetrical, and can be either axonal or schwann cell predominant, and affects strength, balance, proprioception, and light touch. ...Read moreSee 2 more doctor answers
A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more
↑glucose most common: basis neuropathy; Google: "peripheral neuropathy etiology", yet many other associations exist, note word association; Why? Data about associations; mechanisms not fully understood. Cholesterol is part of every animal cell, enables cell membrane flexibility & has never been correct issue despite promotioin by NIH.gov as surrogate for Lipoproteins. Hi odds stress/anger/fear an issue; more complex. ...Read more
Maybe in part: We are increasingly learning that small fibre neuropathies are common, especially associated with diabetes, but also present even in some fibromyalgia cases. A medical food metanx, may result in increased nerve fiber density in the skin after 6-12 months. If the cause is due to an immune polyneuritis, ivig can reverse much of it. Need to understand causation to treat successfully. ...Read more
Peripheral neuropath: Small fiber neuropathy is a peripheral neuropathy that occurs from damage to small unmyelinated nerve fibers present in skin, peripheral nerves, and organs.The role of these nerves is to innervate the skin (somatic fibers) and help control autonomic function (autonomic fibers). It is estimated that 15-20 million people in the USA have some form of peripheral neuropathy. ...Read more
Possibly: The prevalence of neuropathy among patients with celiac disease is much higher than in healthy people. Sometimes, the neurological problems arise from nutritional deficiencies due to malabsorption. However, some cases are due to autoimmunity and associated with the underlying disease (Celiac). ...Read more
Good question: This type of neuropathy is associated with tingling and numbness, of the hands and feet. Often a neurologist will do a nerve conduction test and it will be negative. This is because the nerves effected are very small and cannot be picked up with this test. There is a good test to DX this: skin biopsy looking at nerve fiber density. Look for a neurologist specializing in neuropathy; they do this. ...Read moreSee 1 more doctor answer
DEFINITIONS: Peripheral neuropathy is generic term for abnormal nerves in limbs. Many of these involve large fibers which can cause weakness, numbness, imbalance. The small fiber neuropathy presents with pain, decrease in pin and temperature sensation and caused by a limited number of conditions. Both large and small fibres may be involved in peripheral nerve disorder. ...Read moreSee 1 more doctor answer
I was dx'd with small fiber autonomic polyneuropathy with microvascular injury syndrome on skin biopsy. What are treatments and prognosis will ivig he?
SOMEWHAT UNCLEAR: Not fully clear as to how a skin punch biopsy can lead to your diagnoses, as all that is usually seen is the number and density of your small fibres. Vascular problems are tough to see on the biopsy, and the fibres involve temperature and pain sensations, not autonomic functions. Would highly recommend a second opinion from a medical school specialist to clarify this. ...Read moreSee 1 more doctor answer
Neuropathy: depending on the cause. most of them, the most common types, spread slowly or static. ...Read more
Emg study of feet reads a fairly symmetric mild sensorimotor peripheral neuropathy with primarily axonal loss features. liver, sugar clean.Thoughts?
How quick can small fiber neuropathy progress?I exercise 3-4 times/week. What can I do stop the progression of idiopathic small fiber neuropathy?
Alpha Lipoic Acid: A natural supplement called Alpha Lipoic Acid is used to help the nerves damaged by neuropathy. One needs to take a therapeutic dose - 1200 mg daily. Ask your doc about it. Also, good quality marine fish oil and / or coconut oil to help coat the nerves may help. B12 (sublingual) is also used. Peace and good health. ...Read more
Small Fiber Neuro: Spinal cord stimulator has been shown to be effective in treating a number of chronic pain situations such as chronic pain, such as failed back surgery syndrome, complex regional pain syndrome, ischemic and coronary artery disease. There is also a case report showing the successful treatment of small fiber neuropathy with spinal cord stimulation from georgetown university. ...Read more
Talk to your doctor: There is no current treatment to cure autoimmune small fiber peripheral neuropathy, however, intravenous immunoglobulin (IVIG) therapy is often used as is plasmapheresis. Each has potential risks/benefits, which you will need to understand before choosing either therapy or an alternative therapy. Speak to the doctor who ordered the diagnostic test(s) for recommendations. Hope you feel better soon! ...Read moreSee 1 more doctor answer
A bunch of things: The most common cause I this country would likely be diabetes. However, the list of possible causes is very large, some examples idiopathic (we can not find an answer), thyroid disease, certain toxin exposures, vitamin deficiencies, injuries to the distal (far end) of the nerve, and genetic disease just to name a few. A good thorough work up often, but not always finds the answer. ...Read moreSee 2 more doctor answers
Depends on cause: Do you indeed possess biopsy proven small fibre neuropathy, and have blood and urine studies been completed to uncover causation? (gastroparesis and small fibre issues can be seen in diabetes for example.) sometimes, an increase in fiber consumption will help. Although the medical food metanx may help peripheral nerves, not clear if it affects gastroparesis, but worthwhile trying. ...Read more
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