Doctor insights on:
Small Cell Lung
Small cell & chemo:
Why you can't use chemo?
Small cell lung cancer is very responsive to chemo, which is the mainstay treatment in small cell lung cancer. So, you really need to know why chemo can't be used. It is also sensitive to radiation, but the role of radiation is limited only for limited disease combined with chemo and only for palliative use (relieving pain) in advanced stage. D/w your oncologist in detail. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
Limited: Most with this diagnosis have less than 2 years of survival, unless found when small and peripheral so it can be removed! ...Read more
Rarely is cured.: It depends on the stage and if the cancer has spread. Small cell lung carcinoma is usually treated with chemotherapy and radiation. It is one of the most aggressive subtypes of lung cancer. Definitely consult with an oncologist, but patients with small cell should weigh the benefits of participating in treatment offered in clinical trials at university centers. ...Read more
Diagnostic test: First of all, a biopsy needs to be done to establish a diagnosis. Once is confirmed, then staging work-up needs to be done that include- ct scan; a bone scan and imaging for the head- MRI brain will be preferable than ct scan- if possible. Discuss further with your oncologist. ...Read more
Lung cancer: Small ("oat") cell lung cancer is distinguished by the fact that is has almost always spread beyond the lung when discovered and is therefore not surgically curable, but responds very well to initial chemotherapy. Now that the other common types are coming to be more treatable as well, "non-small cell" is giving way to more elaborate diagnostic schemes. Good luck ; keep up hope. ...Read more
Hard to tell:
Small cell lung cancer is a rapid growing cancer, but the exact size change in a particular patient is often hard to predict. Several factors affect the growth of tumors in a person, including immune factors and genetic factors.
But in general, once small cell lung cancer is diagnosed, it is never just watched, so it is hard to see how fast it will grow. ...Read more
Neuroendocrine tumor: Primary lung lesions are comprised mainly of malignant cells of the bronchus or squamous cell cell and malignant cells of lung glandular tissue or adenocarcinoma of lung. The 3 rd tumor is neuroendocrine or small cell Ca. It is similar in structure and response to the carcinoid of bowel.Tumors other than mets are therefore classed as small cell and non small cell tumors. ...Read more
End of life: If small cell carcinoma is terminal, it means that all means of treatment have failed. Symptoms, including shortness of breath, fatigue, and pain will become more pronounced. This is the time to have comfort care measures in place to make the end as bearable as possible. Pain control at this point is critical. ...Read more
Yes: Small cell carcinomas may arise in many organs. They typically show evidence of differentiation toward certain glandular structures, called 'neuroendocrine' differentiation. Small cell cancers tend to be rapidly proliferating tumors, and thus may be treated initially with chemotherapy. ...Read more
How likely is it for someone who has never smoked or been around smokers to be diagnosed with small cell lung cancer?
Dads friend diagnosed with stage 1 non small cell lung adenocarcinoma. Is there a chance of complete cure since its only stage 1?
Yes: Stage 1 adeno ca of the lung is generally resectable and therefore has a reasonably good prognosis ...Read more
Would you have symptoms of small cell lung cancer for 18 months prior to diagnosis, or does small cell grow too rapidly for this to happen?
Depends on the grade: After a biopsy, when small cell carcinoma is diagnosed, it is often given a "grade" by the pathologist (e.g., low-grade or high-grade) based on the appearance under a microscope. There are small cell cancers that can grow slowly, & only be discovered on screening CT scans (not causing any symptoms). Others cause symptoms & spread quickly (high-grade). Not all small cell cancers behave alike. ...Read more
Is it true that small cell lung cancer is considered a sleeper cell where it only presents itself aggressively in the final stages? Making sense of dx
Interesting term: All cancers can display a wide range of behavior, from very slow, to very fast growing. This is true even of small cell cancer, which has a well-earned reputation of growing rapidly and spreading early, often before it's detected. I've never heard the term "sleeper cell" used in this field, but if it applies anywhere, this might be a reasonable description of all lung cancer, esp small cell. ...Read more
Small cell Lung ca: Smoking tobacco significantly increases the risk of small cell carcinoma. Some hypothesize the impact of carcinogenic smoke on the central airways may be the primary mechanism of injury. The earlier in life a person starts smoking, the more often a person smokes, and the more years a person smokes, the greater the risk of lung cancer. ...Read more
Small cell lung ca: In limited disease, tx would be combination chemo and radiation. In a very limited case, surgery can be done if size is very small, absolutely no spreading to any area/adjacent lymp glands etc. Prophylactic radiation to brain is recommended. In extensive disease, chemo will be the tx. Palliative radiation as needed. For chemo responder, prophylactic radiation to brain can increase survival. D/w md. ...Read more
Ecog ps (performance status) refers to the functional status of patients with cancer (any type, not just small cell). Ps 2 describes pts that " are ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours"
ps scores are used to decide how intense of treatment cancer patients should undergo. ...Read more
Not enough space: Let's see: most common category of lung cancer, often but not always tobacco related, treated with surgery if possible but radiation and chemo are often used as well. I suggest you visit the national cancer institute website. It's has good info regarding all kinds of cancers. ...Read more
Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read more
5yr suvival bystage:
Ia = 49%
ib = 45%
iia = 30%
iib = 31%
iiia = 14%
iiib = 5%
iv = 1%
http://www. Cancer. Org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates. ...Read more